MK-0591

Quiflapon

HCID 60923

基本情報

CAS: 136668-42-3
標準SMILES: CC(C)(C)Sc1c(CC(C)(C)C(=O)O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc4ccccc4n3)cc12
InChIKey: NZOONKHCNQFYCI-UHFFFAOYSA-N
分子式: C34H35ClN2O3S
平均分子量: 587.2 g/mol
単同位体質量: 586.20569166

概要

Quiflapon is a small molecule drug. The usage of the INN stem '-flapon' in the name indicates that Quiflapon is a 5-lipoxygenase-activating protein (FLAP) inhibitor. Quiflapon has a monoisotopic molecular weight of 586.21 Da.

名称と識別子

優先名称: Quiflapon
IUPAC: 3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid
現地名: MK-0591
英語名: Quiflapon
分子式: C34H35ClN2O3S
分子量: 587.17

名称と別名

Quiflapon136668-42-3MK-0591MK 591MK 0591L-686,7089295C885I4DTXSID201598821H-Indole-2-propanoic acid, 1-((4-chlorophenyl)methyl)-3-((1,1-dimethylethyl)thio)-alpha,alpha-dimethyl-5-(2-quinolinylmethoxy)-1H-Indole-2-propanoic acid, 1-[(4-chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-alpha,alpha-dimethyl-5-(2-quinolinylmethoxy)-quiflaponumMK591 compound

名称をさらに表示

1-(4-クロロベンジル)-3-(tert-ブチルチオ)-α,α-ジメチル-5-(2-キノリルメトキシ)-1H-インドール-2-プロパン酸3-[1-(4-クロロベンジル)-3-[(1,1-ジメチルエチル)チオ]-5-[(キノリン-2-イル)メトキシ]-1H-インドール-2-イル]-2,2-ジメチルプロパン酸キフラポン3-[3-(tert-ブチルスルファニル)-1-[(4-クロロフェニル)メチル]-5-[(キノリン-2-イル)メトキシ]-1H-インドール-2-イル]-2,2-ジメチルプロパン酸MK 591(Quiflapon)MK-0591 (Quiflapon)Quiflapon, 10 mM in DMSOMK-591MK0591MK591,FLAP,inhibit,5-LO activating protein,Quiflapon,MK 591,Inhibitor,Apoptosis3-(3-(tert-Butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-indol-2-yl)-2,2-dimethylp

RefChem:178139DTXCID40823733-(TERT-BUTYLTHIO)-1-(P-CHLOROBENZYL)-ALPHA,ALPHA-DIMETHYL-5-(2-QUINOLYLMETHOXY)INDOLE-2-PROPIONATEQuiflapon [INN]Quiflapon free acid3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-indol-2-yl)-2,2-dimethylpropanoic acidL-686708