アクリル酸２－ヒドロキシプロピル

アクリル酸２－ヒドロキシプロピル · 2-ヒドロキシプロピルアクリレ-ト · 2-ヒドロキシプロピルアクリレート · アクリル酸２ヒドロキシプロピル · アクリル酸-2-ヒドロキシプロピル · 2-ヒドロキシプロピル＝アクリラート · アクリル酸(2-ヒドロキシプロピル) · 2-ヒドロキシプロピルアクリラート

https://huagongshe.com/ja/chemical/61249

識別子と物理属性

CAS No.	999-61-1
分子式	C6H10O3
平均分子量	130.14 g/mol
単同位体質量	130.06299418 g/mol
SMILES	C=CC(=O)OCC(C)O
InChIKey	GWZMWHWAWHPNHN-UHFFFAOYSA-N
PubChem CID	61249
ChEMBL	CHEMBL3184912
EC No.	213-663-8
DTXSID	DTXSID0022143
現地名	アクリル酸２－ヒドロキシプロピル

化学・物理的性質

XLogP	0.3
極性表面積	46.5
水素結合供与体数	1
水素結合受容体数	3
回転可能結合数	4
重原子数	9
形式電荷	0
複雑度	109
物質分類	Corrosives
Polymers	Plastics & Rubber -> (Meth)acrylates
LogP（分配係数）	log Kow = 0.35
密度	1.05 kg/L at 25 °CRelative density (water = 1): 1.11.06 g/cm3
Color/Form	LiquidColorless liquid
溶解度	Miscible with waterMiscible with oxygenated solventsSolubility in water, g/100ml at 25 °C: 100 (good)Chloroform (Slightly), Methanol (Sparingly)
引火点	149 °F (closed cup)65 °C207 °F
沸点	BP: 70 °C at 2 mm HgBP: 63 °C at 0.04 kPa (0.3 mm Hg)BP: 77 °C at 5 mm Hg191 °C376 °F77°C 5mm
Decomposition	When heated to decomposition it emits acrid smoke and fumes.Hazardous decomposition products formed under fire conditions. - Carbon dioxide (CO2)
蒸気密度	Relative vapor density (air = 1): 4.5
Polymerization	If the material is subject to heat or becomes contaminated, it is liable to polymerize with the release of heat.
蒸気圧	0.17 [mmHg]Vapor pressure, Pa at 20 °C: 5
屈折率	1.4315 (estimate)
pKa（酸解離定数）	13.92±0.20(Predicted)
外観・状態	透明から淡黄色の液体
ヘンリー定数	1.6×103 mol/(m3Pa) at 25℃, HSDB (2015)
化粧品成分の機能	フィルム形成
CAS データベース	999-61-1(CAS DataBase Reference)
EPAの化学物質情報	2-Hydroxypropyl acrylate (999-61-1)

化学的特性

A liquid.

安全性と法規制

GHS 分類	DangerH301: Toxic if swallowed [Danger Acute toxicity, oral]P260, P261, P262, P264, P270, P271, P272, P280, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P330, P333+P317, P361+P364, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)H301+H331 (25.9%): Toxic if swallowed or if inhaled [Danger Acute toxicity, oralacute toxicity, inhalation]P260, P261, P262, P264, P264+P265, P270, P271, P272, P273, P280, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P333+P317, P361+P364, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)
規制情報	Chemical: 2-Propenoic acid, 2-hydroxypropyl ester2-Hydroxypropyl acrylate: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
火災危険	Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Above 65 °C explosive vapour/air mixtures may be formed.
有害性の概要	May cause skin burnsmay cause pulmonary edema after heavy inhalation exposure[ICSC] A potential dermal sensitizer, based on weak animal dataRats died after 4-hour exposures to 650 ppm and showed signs of eye, nasal, and respiratory irritation. [ACGIH]
EC 分類	Symbol: TR: 23/24/25-34-43S: (1/2)-26-36/37/39-45Note: C, D
UN 分類	UN Hazard Class: 6.1UN Subsidiary Risks: 8UN Pack Group: I
Chemical Dangers	The substance may polymerize due to heating and under the influence of light, and peroxides. Decomposes on heating. This produces toxic and corrosive fumes including acrolein. Reacts violently with strong acids, strong bases, strong oxidants and peroxides. This generates fire hazard.

用途

熱硬化性塗料?接着剤原料、繊維処理剤、コポリマーの改質剤 (化学工業日報社)

説明

A case of occupational contact dermatitis caused by exposure to 2-hydroxypropyl acrylate was reported in industry.

使用

In manufacture of thermosetting resins for surface coatings.