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Uranium tetrafluoride

HCID 61461
ノート反応
基本情報概要名称と識別子物性安全と法規制化学と産業関連反応化合物ノート
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基本情報

CAS
10049-14-6
標準SMILES
[F][U]([F])([F])[F]
InChIKey
MZFRHHGRNOIMLW-UHFFFAOYSA-J
分子式
F4U
平均分子量
314.0225 g/mol
単同位体質量
314.0444

概要

Uranium pentafluoride is a fluoride of uranium. Uranium is a chemical element that has the symbol U and atomic number 92. It is a normal part of rocks, soil, air, and water, and occurs in nature in the form of minerals. (L248, L249)

名称と識別子

優先名称
Uranium tetrafluoride
IUPAC
tetrafluorouranium

名称と別名

Uranium florideUranium fluoride (U2F8)PJ46VTD8B2DTXSID30892258RefChem:193202DTXCID201079321233-170-110049-14-6Uranium fluoride (UF4)Uranium fluoride (UF4), (T-4)-Uranium tetrafluoridetetrafluorouranium
名称をさらに表示
UrantetrafluoridEINECS 233-170-1UNII-PJ46VTD8B2Uranium(4+) tetrafluorideSCHEMBL10704137

データベース識別子

CAS
10049-14-6
PubChem CID
61461
DTXSID
DTXSID30892258
EC Number
233-170-1

物性

構造計算による物性

極性表面積
0 Ų
水素結合供与体数
0
水素結合受容体数
4
回転可能結合数
0
重原子数
5
形式電荷
0
複雑度
19.1

実験および物理化学的性質

Chemical ClassesPhysical/Radiation -> Radioactive Compounds
Physical DescriptionGreen crystals; [Merck Manual]

安全と法規制

安全情報は参考情報です。供給元の安全データシート(SDS)、適用法令、専門家による評価に代わるものではありません。

危険有害性情報

Hazards SummarySee Uranium and linked occupational diseases.

安全と保護具

Exposure Control and Personal Protection · 2 件

Biological Exposure Indices (BEI) [ACGIH] - Fluorides in urine = 2 mg/L prior to shift or 3 mg/L at end of shift; (Repeated measurements recommended.) Uranium in urine = 200 ug/L at end of shift;

1.0 [mg/m3], as F, inhalable fraction[German Research Foundation (DFG)]

Minimum Risk Level · 1 件

Intermediate Inhalation: 0.0004 mg/m3 (Soluble uranium salts) (L134) Chronic Inhalation: 0.0003 mg/m3 (Soluble uranium salts) (L134) Intermediate Oral: 0.002 mg/kg/day (Soluble uranium salts) (L134) Intermediate Inhalation: 0.008 mg/m3 (Insoluble uranium compounds) (L134)

Threshold Limit Values (TLV) · 2 件

0.2 [mg/m3], as U (2.5 mg/m3, as F)

0.6 [mg/m3], as U

Permissible Exposure Limit (PEL)0.05 [mg/m3], as U (sol), 0.25 mg/m3, as U (insol) [2.5 mg/m3, as F]
Immediately Dangerous to Life or Health (IDLH)10.0 [mg/m3], as U

毒性情報

Treatment · 1 件

EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration.

化学と産業

薬理情報

Metabolism/Metabolites · 1 件

Uranium is absorbed in low amounts via oral, inhalation, and dermal routes. Uranium in body fluids generally exists as the uranyl ion (UO2)2+ complexed with anions, such as citrate and bicarbonate, or plasma proteins. Uranium preferentially distributes to bone, liver, and kidney. The large majority of uranium that enters the body is not absorbed and is eliminated from the body via the urine and faeces. (L248)

用途と製造

General Manufacturing InformationUranium fluoride (UF4), (T-4)-: INACTIVE

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化合物ノート

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このページの内容基本情報概要名称と識別子物性安全と法規制化学と産業関連反応化合物ノート
Health Effects · 1 件

Uranium primarily damages the kidney, but may also damage the lungs, central nervous system, and immune system. Uranium's radioactivity is believed to damage the DNA, resulting in carcinogenic effects and reproductive and developmental damage. (L248, L249)

Exposure RoutesOral (L249) ; inhalation (L249) ; dermal (L249)
Toxicity Summary · 1 件

Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and proteins in the tubular wall, causing damage. Uranium may also inhibit both sodium transport-dependent and independent ATP utilization and mitochondrial oxidative phosphorylation in the renal proximal tubule. Uranium causes respiratory diseases by damaging alveolar epithelium type II cells in the lungs. Uranium induces c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (p38 MAPK) activation, which in turn induces tumor necrosis factor alpha (TNF-alpha) secretion and generates and inflammatory response in the lungs. Studies have shown that the more soluble the uranium salt, the more toxic it is. Ionizing radiation produced by uranium damages the DNA, resulting in gene mutations and chromosomal aberrations. This can both both initiate and promote carcinogenesis, and interfere with reproduction and development. (L249, A160)

Signs and SymptomsIngestion of uranium may cause vomiting and diarrhea. (L248)
Carcinogen ClassificationUranium: Group 1, carcinogenic to humans (L135)