ナトリウム チオサルフェト 五水和物
Sodium Thiosulfate Pentahydrate
基本情報
- CAS
10102-17-7- 標準SMILES
O.O.O.O.O.O=S([O-])([O-])=S.[Na+].[Na+]- InChIKey
PODWXQQNRWNDGD-UHFFFAOYSA-L- 分子式
- H10Na2O8S2
- 平均分子量
- 248.19 g/mol
- 単同位体質量
- 247.96124818
概要
Sodium thiosulfate pentahydrate is a hydrate consisting of sodium thiosulfate with 5 mol eq. of water. It has a role as a nephroprotective agent, an antifungal drug and an antidote to cyanide poisoning. It contains a sodium thiosulfate.
名称と識別子
- 優先名称
- Sodium Thiosulfate Pentahydrate
- IUPAC
- disodium;dioxido-oxo-sulfanylidene-λ6-sulfane;pentahydrate
- 現地名
- ナトリウム チオサルフェト 五水和物
- 英語名
- Sodium thiosulfate pentahydrate
- 分子式
- H10Na2O8S2
- 分子量
- 248.18
名称と別名
SODIUM THIOSULFATE PENTAHYDRATE10102-17-7Disodium thiosulfate pentahydrateAntichlorSodium thiosulfate, pentahydrateThiosulfuric acid (H2S2O3), disodium salt, pentahydrateDTXSID6044197CHEBI:32150pentahydrate of sodium thiosulfateRefChem:931939DTXCID4024197600-156-5
名称をさらに表示
チオ硫酸ナトリウム五水和物ナトリウム チオサルフェト 五水和物チオ硫酸ナトリウム五水和物(結晶)0.005MOL/L(N/200) チオ硫酸ナトリウム溶液0.01MOL/L(N/100) チオ硫酸ナトリウム溶液0.01MOL/L(N/100)チオ硫酸ナトリウム溶液0.025MOL/L(N/40) チオ硫酸ナトリウム溶液0.02MOL/L(N/50) チオ硫酸ナトリウム溶液0.05MOL/L(N/20) チオ硫酸ナトリウム溶液0.1MOL/L(N/10) チオ硫酸ナトリウム溶液0.2MOL/L(N/5) チオ硫酸ナトリウム溶液1/3MOL/L チオ硫酸ナトリウム溶液1MOL/L(1N) チオ硫酸ナトリウム溶液20W/V% チオ硫酸ナトリウム溶液チオ硫酸ナトリウム, 5水和物ハイポ, 5水和物チオ硫酸ナトリウム五水和物 ACS REAGENT,≥99.5%チオ硫酸ナトリウム五水和物 FOR MASS SPECTROMETRY,≥99.5% (T)チオ硫酸ナトリウム五水和物 PURISS. P.A.,ACS REAGENT,REAG. ISO,REAG. PH. EUR.,≥99.5%
物性
構造計算による物性
- 極性表面積
- 109 Ų
- 水素結合供与体数
- 5
- 水素結合受容体数
- 9
- 回転可能結合数
- 0
- 重原子数
- 12
- 形式電荷
- 0
- 複雑度
- 82.6
実験および物理化学的性質
Chemical ClassesOther Classes -> Sulfur Compounds
Density1.69 @25 °C
Melting Point48 °C
Physical Description
Large Crystals; Dry Powder; Other Solid
Odorless solid; Deliquesces slightly in moist air; [Merck Index] Colorless odorless crystalline solid; [Sigma-Aldrich MSDS]
物理化学的性質
- 融点
- 48.5 °C · 48.5 °C
- 沸点
- 100 C · 100 C
- 比重(密度)
- 1.01 g/mL · 1.01 g/mL at 25 °C
- 屈折率
- 1.489 · 1.489
- 貯蔵温度
- 5 °C · Store at +5°C to +30°C.
- 溶解性
- 2 O: · H2O: 1M at20℃、透明、無色
- 外見
- 個体
- 色
- 白透明
- 比重
- 1.729 · 1.729
- 臭い (Odor)
- 無臭
- PH
- 6 · 6.0-7.5 (100g/l, H2O, 20℃)
- 水溶解度
- 680 g/L · 680g/L（20℃）
- Merck
- 14 · 14,8694
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
This chemical does not meet GHS hazard criteria for 98.6% (277 of 281) of all reports.
Not Classified
Aggregated GHS information provided per 281 reports by companies from 6 notifications to the ECHA C&L Inventory.
危険有害性情報
Regulatory Information
Chemical: Thiosulfuric acid (H2S2O3), disodium salt, pentahydrate
Thiosulfuric acid (H2S2O3), disodium salt, pentahydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Thiosulfuric acid (H2S2O3), disodium salt, pentahydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Sodium thiosulfate pentahydrate: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Thiosulfuric acid (H2S2O3), disodium salt, pentahydrate: Human health tier I assessment
Hazards Summary
Causes convulsions, ataxia, and lung changes in intravenous lethal-dose studies of mice; Causes increased pulse rate and respiratory stimulation in intravenous lethal-dose studies of dogs; [RTECS] Not considered hazardous by GHS classification; [Sigma-Aldrich MSDS] See Sodium thiosulfate.
EPA Safer ChemicalChemical: Sodium thiosulfate, pentahydrate
Hazard Classes and CategoriesNot Classified
安全と保護具
Protective Action Criteria (PAC)
化学と産業
薬理情報
MeSH Pharmacological Classification
Agents counteracting or neutralizing the action of POISONS.
Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues.
Drugs used in the treatment of tuberculosis. They are divided into two main classes: first-line agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and second-line drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy.
Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS.
用途と製造
Uses
Used to remove chlorine from solutions; to bleach paper, bone, straw, and ivory; as a fixer in photography; to extract silver from ores; as mordant in dyeing and printing textiles; in leather manufacturing; in pharmaceutical production (antioxidant), and as an antidote for cyanide poisoning; [Merck Index] Permitted for use as an inert ingredient in non-food pesticide products; [EPA]
Pulp and Paper Processing [Category: Industry]
U.S. Production2023: 4,000,000 - <5,500,000 lb
Consumer UsesNot Known or Reasonably Ascertainable
Industry UsesLaboratory chemicals
Use Classification
EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives
Safer Chemical Classes -> Green half-circle - The chemical is expected to be of low concern
General Manufacturing InformationTextiles, apparel, and leather manufacturing
関連反応
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