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クロム酸ジセシウム
クロム酸ジセシウム · クロム酸二セシウム · クロム酸セシウム, 99.9% (metals basis) · Caesiumchromate · CESIUM CHROMATE · dicesium chromate · Cesium chromate(VI) · Chromicacid,dicesiumsalt
識別子と物理属性
| CAS No. | 13454-78-9 |
|---|---|
| 分子式 | CrCs2O4 |
| 平均分子量 | 381.805 g/mol |
| 単同位体質量 | 381.73106978 g/mol |
| SMILES | [Cs+].[Cs+].[O]=[Cr](=[O])([O-])[O-] |
| InChIKey | BROHICCPQMHYFY-UHFFFAOYSA-N |
| PubChem CID | 61613 |
| EC No. | 236-640-4 |
| DTXSID | DTXSID20894903 |
| 現地名 | クロム酸ジセシウム |
化学・物理的性質
| 極性表面積 | 80.3 |
|---|---|
| 水素結合供与体数 | 0 |
| 水素結合受容体数 | 4 |
| 回転可能結合数 | 0 |
| 重原子数 | 7 |
| 形式電荷 | 0 |
| 複雑度 | 62.2 |
| 物質分類 | Metals -> Chromium Compounds, Inorganic |
| Physical Description | Yellow odorless powderSoluble in water[MSDSonline] |
| 外観・状態 | 粉 |
| 溶解度 | 水に溶ける。 |
| InChI | 1S/Cr.2Cs.4O/q2*+12*-1 |
| InChIKey | BROHICCPQMHYFY-UHFFFAOYSA-N |
| SMILES | [Cs+].[Cs+].[O-][Cr]([O-])(=O)=O |
| CAS データベース | 13454-78-9(CAS DataBase Reference) |
| EPAの化学物質情報 | Chromic acid (H2CrO4), dicesium salt (13454-78-9) |
安全性と法規制
| GHS 分類 | DangerH272 (94.4%): May intensify fireoxidizer [Danger Oxidizing liquidsOxidizing solids]P203, P210, P220, P261, P264, P264+P265, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P370+P378, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 72 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.H272 (88.4%): May intensify fire |
|---|---|
| 有害性の概要 | CrVI compounds are irritants, sensitizers, and may be corrosive to the skin. CrVI compounds are respiratory tract irritants and may cause pulmonary sensitization. CrVI may cause acute tubular necrosis and liver injury. [ATSDR Case Studies] May cause fire in contact with combustible materialA corrosive substance that can cause injury to the skin, eyes, and respiratory tractMay cause skin sensitization[MSDSonline] See Chromium and linked occupational diseases. |
| Hazard Classes and Categories | Ox. Sol. 2 (94.4%)Ox. Sol. 2 (88.4%) |
| 暴露管理・個人防護 | Biological Exposure Indices (BEI) [ACGIH] - For chromium (VI), water-soluble fume: Total Cr in urine = 10 ug/L (increase during shift) or 25 ug/L (end of shift at end of workweek) |
| Minimum Risk Level | Intermediate Oral: 0.005 mg/kg/day (L134) Chronic Oral: 0.001 mg/kg/day (L134) |
| Threshold Limit Values (TLV) | 0.0002 [mg/m3], as Cr(VI), inhalable particulate matter0.0005 [mg/m3], as Cr(VI), inhalable particulate matter |
| Permissible Exposure Limit (PEL) | 0.005 [mg/m3], as Cr(VI) |
| Treatment | There is no know antidote for chromium poisoning. Exposure is usually handled with symptomatic treatment. (L16) |
| 健康影響 | Hexavalent chromium is a known carcinogen. Chronic inhalation especially has been linked to lung cancer. Hexavalent chromium has also been know to cause reproductive and developmental defects. (A12) |
| 有害作用 | Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation. |
| 暴露経路 | Inhalation (L16)oral (L16)dermal (L16) |
| 毒性の概要 | Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produced during reoxidation of pentavalent chromium by hydrogen peroxide molecules present in the cell. Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, chromium-DNA adducts, chromosomal aberrations and alterations in cellular signaling pathways. It has been shown to induce carcinogenesis by overstimulating cellular regulatory pathways and increasing peroxide levels by activating certain mitogen-activated protein kinases. It can also cause transcriptional repression by cross-linking histone deacetylase 1-DNA methyltransferase 1 complexes to CYP1A1 promoter chromatin, inhibiting histone modification. Chromium may increase its own toxicity by modifying metal regulatory transcription factor 1, causing the inhibition of zinc-induced metallothionein transcription. (A12, L16, A34, A35, A36) |
| Signs and Symptoms | Breathing hexavalent chromium can cause irritation to the lining of the nose, nose ulcers, runny nose, and breathing problems, such as asthma, cough, shortness of breath, or wheezing. Ingestion of hexavalent chromium causes irritation and ulcers in the stomach and small intestine, as well as anemia. Skin contact can cause skin ulcers. (L16) |
| Carcinogen Classification | 1, carcinogenic to humans. (L135) |
| 水環境危害等級（WGK） | 3 |
| TSCA 収載状態 | TSCA listed |
| 輸送番号（UN） | UN 1479 5.1/PG 2 |
| 危険文句（R） | 45-46-8-36/37/38-50/53-43-49 |
| 危険表示 | O,T,N |
| 安全措置（S） | 53-17-26-27-36/37/39-45-61-60 |
| 危険等級 | 5.1Aquatic Acute 1Aquatic Chronic 1Carc. 1BOx. Sol. 2Skin Sens. 1 |
| 包装等級 | III |
| 特定化学物質 | 特38-309 |
| 貯蔵分類 | 5.1B - Oxidizing hazardous materials |
用途
使用
Cesium chromate is used to produce cesium vapor by reaction with silicon, boron, or titanium, which is used in the final stages of creating vacuum tubes. It is used in the production of photo-tubes.