化工社化工社 化学情報印刷レポート · 研究参考用
アンモニウム高級アルコ-ルエトキシサルフェ-ト
アンモニウム高級アルコ-ルエトキシサルフェ-ト · ラウレス－２硫酸アンモニウム · ラウレス－３硫酸アンモニウム · ales · AMMONIUM LAURYL ETHER SULFATE · DP-70 · POE(1) · C12H26Na2O5S
識別子と物理属性
| CAS No. | 32612-48-9 |
|---|---|
| 分子式 | C14H33NO5S |
| 平均分子量 | 327.48 g/mol |
| 単同位体質量 | 327.20794433 g/mol |
| SMILES | CCCCCCCCCCCCOCCOS(=O)(=O)O.N |
| InChIKey | OPVLOHUACNWTQT-UHFFFAOYSA-N |
| PubChem CID | 61913 |
| EC No. | 608-760-0 |
| 現地名 | アンモニウム高級アルコ-ルエトキシサルフェ-ト |
化学・物理的性質
| 極性表面積 | 82.2 |
|---|---|
| 水素結合供与体数 | 2 |
| 水素結合受容体数 | 6 |
| 回転可能結合数 | 15 |
| 重原子数 | 21 |
| 形式電荷 | 0 |
| 複雑度 | 284 |
| Physical Description | Light yellow viscous liquid[MSDSonline] |
| 化粧品成分の機能 | クレンジング界面活性剤 - 洗浄発泡 |
| LogP（分配係数） | 5.405 (est) |
| CAS データベース | 32612-48-9 |
| EPAの化学物質情報 | Polyethylene glycol lauryl ether sulfate ammonium salt (32612-48-9) |
化学性质
EO付加モル数分布が狭い，副生物が少ない
安全性と法規制
| GHS 分類 | This chemical does not meet GHS hazard criteria for 12.6% (59 of 469) of reports.DangerH315 (87.4%): Causes skin irritation [Warning Skin corrosion/irritation]H318 (12.4%): Causes serious eye damage [Danger Serious eye damage/eye irritation]H319 (75.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]P264, P264+P265, P280, P302+P352, P305+P351+P338, P305+P354+P338, P317, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement)Aggregated GHS information provided per 469 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Reported as not meeting GHS hazard criteria per 59 of 469 reports by companies.There are 5 notifications provided by 410 of 469 reports by companies with hazard statement code(s).Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| 規制情報 | Chemical: Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1)Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Poly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, ammonium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).Poly(oxyethylene) lauryl ether ammonium sulfate: Does not have an individual approval but may be used under an appropriate group standard |
| その他の安全情報 | IMAP assessments - Sodium and ammonium laureth sulfate: Human health tier II assessment |
| 有害性の概要 | An eye irritant[MSDSonline] |
| EPA Safer Chemical | Chemical: Ammonium Laureth SulfateGreen circle - The chemical has been verified to be of low concern based on experimental and modeled data. |
| Hazard Classes and Categories | Skin Irrit. 2 (87.4%)Eye Dam. 1 (12.4%)Eye Irrit. 2 (75.1%)Not ClassifiedAcute toxicity - category 4Eye irritation - category 2ASkin irritation - category 2 |
| 健康影響 | Ammonium laureth sulfate itself only causes mild irritation. However, it may react to produce nitrosamines, which are believed to be carcinogenic. (L1888, L1890) |
| 暴露経路 | Oral (A2880)inhalation (A2880)dermal (L1889) |
| 毒性の概要 | Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.orgWhile ammonium laureth sulfate itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosamines are produced from secondary amines and amides in the presence of nitrite ions and are believed to be carcinogenic. Once in the body, nitrosamines are activated by cytochrome P-450 enzymes. They are then believed to induce their carcinogenic effects by forming DNA adducts at the N- and O-atoms. (L1889, L1890, A2878, A2879, A2880) |
| Signs and Symptoms | Ammonium laureth sulfate can cause mild irritation. (L1888) |
| Carcinogen Classification | Not listed by IARC. Certain nitrosamines are classified by IARC as either probably or possibly carcinogenic to humans (Groups 2A and 2B, respectively). (L135) |
| TSCA 収載状態 | TSCA listed |
用途
用途
界面活性剤，洗浄剤，起泡剤
使用
ammonium laureth sulfate is a surfactant with foaming capabilities. It can also serve as an emulsifying agent and is frequently found in skin cleansers. As a member of the ether sulfate group, it is considered less irritating than its lauryl counterpart, ammonium lauryl sulfate.
製法・合成法
合成方法
MgO系固体塩基触媒を用いたエチレンオキシドの付加反応