α,α,α,α',α',α'-ヘキサクロロ-p-キシレン

Danger

H301 (25%): Toxic if swallowed [Danger Acute toxicity, oral]

P260, P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P361+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 4 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

P-BIS(TRICHLOROMETHYL)BENZENE 100 MG/KG ORALLY DAILY FOR 4 WK IN RATS INCR BODY WT OF 6 OUT OF 7, HAD NO EFFECT ON LIVER OR KIDNEY; 200 MG/KG KILLED 1 & DECR BODY WT & CAUSED VACUOLIZATION OR FATTY DEGENERATION IN LIVER & KIDNEY OF 2 OUT OF 9 RATS.

P-BIS(TRICHLOROMETHYL)BENZENE 300 MG/KG ORALLY & DAILY FOR 4 WK TO RATS INCR BODY WT OF 7 OUT OF 8, HAD NO EFFECT ON LIVER OR KIDNEY, 500 MG/KG DECR BODY WT & CAUSED DEATH IN 3 OUT OF 8 AFTER 8TH, 21ST, & 27TH DOSE. LIVER & KIDNEY SHOWED FATTY DEGENERATION.

100 MG/KG OF DRUG ADMIN ORALLY & DAILY FOR 12 WK INCR BODY WT OF ALL ANIMALS STUDIED, CAUSED NO DEATHS, & HAD NO EFFECT ON LIVER OR KIDNEYS. TRANSIENT HYPOCHROMIC ANEMIA WAS OCCASIONALLY NOTED IN RATS @ ALL DOSE LEVELS (100, 200, 300, 500 MG/KG).

Agents that kill parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal.

Agents used to treat cestode, trematode, or other flatworm infestations in man or animals.

Used as insecticide and veterinary anthelmintic (trematodes); [Merck Index]

Farming (Pesticides) [Category: Industry]

INSECTICIDE; FASCIOLICIDE

MEDICATION (VET)