シュウ酸銀

This chemical does not meet GHS hazard criteria for 4.6% (5 of 109) of reports.

Danger

H201 (95.4%): (Deleted) Explosive; mass explosion hazard [Danger Explosives]

P210, P230, P240, P250, P264, P270, P273, P280, P301+P317, P302+P352, P317, P321, P330, P362+P364, P370+P380, P372, P373, P391, P401, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 109 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Silver oxalate (dry)

Forbidden explosives/materials (49 eCFR § 173.54/§ 173.21)

Silver itself is not toxic to humans, but most silver salts are. In large doses, silver and compounds containing it can be absorbed into the circulatory system and become deposited in various body tissues, leading to argyria, which results in a blue-grayish pigmentation of the skin, eyes, and mucous membranes. Argyria is rare, and although, so far as known, this condition does not otherwise harm a person's health, it is disfiguring and usually permanent. Mild forms of argyria are sometimes mistaken for cyanosis. (L809)

Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, disrupting selenium-catalyzed sulfhydryl oxidation-reduction reactions and intracellular ion concentrations, respectively. Silver nanoparticles are believed to disrupt the mitochondrial respiratory chain, causing oxidative stress, reduced ATP synthesis, and DNA damage. (L808, A243, A244, A245, A246)

Silver and its compounds can be absorbed via inhalation, while silver compounds can also be absorbed orally and dermally. It distributes throughout the body in the blood, particularily to the liver. Insoluble silver salts are transformed into soluble silver sulfide albuminates, bind to amino or carboxyl groups in RNA, DNA, and proteins, or are reduced to metallic silver by ascorbic acid or catecholamines. Metallic silver is oxidized and may deposit in the tissues, causing arygria. Silver is eliminated primarily in the faeces. (L808)