基本情報
- CAS
7701-62-4- 標準SMILES
C[N+](C)(C)CC[N+]1(C)Cc2c(Cl)c(Cl)c(Cl)c(Cl)c2C1- InChIKey
IXWDUZLHWJKVPX-UHFFFAOYSA-N- 分子式
- C14H20Cl4N2+2
- 平均分子量
- 358.1 g/mol
- 単同位体質量
- 356.038059
概要
Chlorisondamine is a member of isoindoles.
名称と識別子
- 優先名称
- 4,5,6,7-Tetrachloro-2,3-dihydro-2-methyl-2-(2-(trimethylammonio)ethyl)-1H-isoindolium
- IUPAC
- trimethyl-[2-(4,5,6,7-tetrachloro-2-methyl-1,3-dihydroisoindol-2-ium-2-yl)ethyl]azanium
- 英語名
- Chlorisondamine
- 分子式
- C14H20Cl4N2+2
- 分子量
- 358.134
名称と別名
ChlorisondamineChlorisondamine ionChlorisondamine cation7701-62-4JD3M24F66IDTXSID0048395Isoindolinium, 4,5,6,7-tetrachloro-2-methyl-2-(2-(trimethylammonio)ethyl)-RefChem:575656DTXCID10283684,5,6,7-Tetrachloro-2,3-dihydro-2-methyl-2-(2-(trimethylammonio)ethyl)-1H-isoindoliumNCGC00163230-01UNII-JD3M24F66I
名称をさらに表示
chlorisondamine-diiodideTocris-10014,5,6,7-Tetrachloro-2-methyl-2-(2-(trimethylammonio)ethyl)isoindoliniumCHEMBL1398654CHLORISONDAMINE [WHO-DD]SCHEMBL14340042BDBM84948CHEBI:135514
データベース識別子
- CAS
7701-62-4- PubChem CID
- 6244
- DTXSID
DTXSID0048395- ChEMBL
CHEMBL1398654- ChEBI
CHEBI:135514- UNII
- JD3M24F66I
- Nikkaji
- J246.997I
物性
構造計算による物性
- XLogP
- 3.9
- 極性表面積
- 0 Ų
- 水素結合供与体数
- 0
- 水素結合受容体数
- 0
- 回転可能結合数
- 3
- 重原子数
- 20
- 形式電荷
- 2
- 複雑度
- 336
化学と産業
薬理情報
MeSH Pharmacological Classification
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.
Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.
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