シプロフロキサシン塩酸塩

Ciprofloxacin Hydrochloride Anhydrous

HCID 62999CAS 86483-48-9

基本情報

標準SMILES
Cl.O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O
InChIKey
DIOIOSKKIYDRIQ-UHFFFAOYSA-N
分子式
C17H19ClFN3O3
平均分子量
367.8 g/mol
単同位体質量
367.1098973

名称と識別子

優先名称
Ciprofloxacin Hydrochloride Anhydrous
IUPAC
1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid;hydrochloride
現地名
シプロフロキサシン塩酸塩
英語名
Ciprofloxacin hydrochloride
分子式
C17H18FN3O3.xHCl
分子量
367.81

名称と別名

93107-08-5Ciprofloxacin Hydrochloride Anhydrous0MP32MFP6CRefChem:91867286483-48-91-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid xhydrochloride1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochlorideCiprofloxacin monohydrochlorideCHEBI:310388Bay o 9867Ciprofloxacin (monohydrochloride)
名称をさらに表示
シプロフロキサシン塩酸塩CIPROFLOXACIN HYDROCHLORIDE MONOHYDRATECiprofloxacin base/HCLCifloxCiprofloxacin Impurity 14CIPROFLOXACIN HCL HYDRATECIPROFLOXACIN HCL (ANHYDROUS)Enrofloxacin nicotinate USP/EP/BP
BAY-O-9867CiproxanCiproxinciprofloxacin hydrochloride (anhydrous)BAY-o 98671-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid;hydrochlorideciprofloxacine hydrochloridePrestwick_67

データベース識別子

CAS
86483-48-9、93107-08-5
PubChem CID
62999
DTXSID
DTXSID1047788
ChEBI
CHEBI:310388
UNII
0MP32MFP6C
EC Number
642-985-5

物性

構造計算による物性

極性表面積
72.9 Ų
水素結合供与体数
3
水素結合受容体数
7
回転可能結合数
3
重原子数
25

物理化学的性質

融点
300 °C · >300 °C
貯蔵温度
Inert atmosphere,Room Temperature
溶解性
DMSO(微加熱)、メタノール(微加熱)
外見
個体
色
ホワイトからオフホワイト
BCS Class
3 · 3/1

安全と法規制

GHS分類

GHS Classification · 5 件

Danger

H315 (33.3%): Causes skin irritation [Warning Skin corrosion/irritation];H317 (66.7%): May cause an allergic skin reaction [Warning Sensitization, Skin];H319 (66.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H334 (66.7%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory];H335 (33.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H400 (33.3%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard];H410 (66.7%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P233, P260, P261, P264, P264+P265, P271, P272, P273, P280, P284, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P391, P403, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 3 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Hazard Classes and CategoriesSkin Irrit. 2 (33.3%);Skin Sens. 1 (66.7%);Eye Irrit. 2 (66.7%);Resp. Sens. 1 (66.7%);STOT SE 3 (33.3%);Aquatic Acute 1 (33.3%);Aquatic Chronic 1 (66.7%)

安全データ

hs_code
29419000
risk_code
36/37/38
hazard_code
Xi
safety_code
26-36

化学と産業

薬理情報

MeSH Pharmacological Classification · 3 件

Substances that inhibit the growth or reproduction of BACTERIA.

Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II.

Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 CYP1A2.

サプライヤー50 社

北京华美互利生物化工010-56205725 · [email protected]
济南百隆化学有限公司[email protected] · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
深圳市健竹科技有限公司0755-89218110 13480856786
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]

補足説明

定義ChEBI: The anhydrous form of the monohydrochloride salt of ciprofloxacin.

関連反応

5 件

関連ノート

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