シプロフロキサシン塩酸塩
Ciprofloxacin Hydrochloride Anhydrous
基本情報
- CAS
86483-48-9- 標準SMILES
Cl.O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O- InChIKey
DIOIOSKKIYDRIQ-UHFFFAOYSA-N- 分子式
- C17H19ClFN3O3
- 平均分子量
- 367.8 g/mol
- 単同位体質量
- 367.1098973
概要
Ciprofloxacin hydrochloride (anhydrous) is the anhydrous form of the monohydrochloride salt of ciprofloxacin. It has a role as an antiinfective agent, an antibacterial drug, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor and a topoisomerase IV inhibitor. It contains a ciprofloxacin.
名称と識別子
- 優先名称
- Ciprofloxacin Hydrochloride Anhydrous
- IUPAC
- 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid;hydrochloride
- 現地名
- シプロフロキサシン塩酸塩
- 英語名
- Ciprofloxacin hydrochloride
- 分子式
- C17H18FN3O3.xHCl
- 分子量
- 367.81
名称と別名
93107-08-5Ciprofloxacin Hydrochloride Anhydrous0MP32MFP6CRefChem:91867286483-48-91-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid xhydrochlorideCiprofloxacin monohydrochloride1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochlorideCHEBI:310388Bay o 9867Ciprofloxacin (monohydrochloride)
名称をさらに表示
シプロフロキサシン塩酸塩CIPROFLOXACIN HYDROCHLORIDE MONOHYDRATECiprofloxacin base/HCLCifloxCiprofloxacin Impurity 14CIPROFLOXACIN HCL HYDRATECIPROFLOXACIN HCL (ANHYDROUS)Enrofloxacin nicotinate USP/EP/BP
BAY-O-9867CiproxanCiproxinciprofloxacin hydrochloride (anhydrous)BAY-o 98671-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid;hydrochloride1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid hydrochlorideciprofloxacine hydrochloride
データベース識別子
- CAS
86483-48-9、93107-08-5- PubChem CID
- 62999
- DTXSID
DTXSID1047788- ChEMBL
CHEMBL1202- ChEBI
CHEBI:310388- UNII
- 0MP32MFP6C
- EC Number
- 642-985-5
物性
構造計算による物性
- 極性表面積
- 72.9 Ų
- 水素結合供与体数
- 3
- 水素結合受容体数
- 7
- 回転可能結合数
- 3
- 重原子数
- 25
- 形式電荷
- 0
- 複雑度
- 571
物理化学的性質
- 融点
- 300 °C · >300 °C
- 貯蔵温度
- Inert atmosphere,Room Temperature
- 溶解性
- DMSO（微加熱）、メタノール（微加熱）
- 外見
- 個体
- 色
- ホワイトからオフホワイト
- BCS Class
- 3 · 3/1
- InChI
- InChI=1S/C17H18FN3O3.ClH/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;/h7-10,19H,1-6H2,(H,23,24);1H
- InChIKey
- DIOIOSKKIYDRIQ-UHFFFAOYSA-N
- SMILES
- O=C1C(=CN(C2CC2)C2=CC(N3CCNCC3)=C(F)C=C12)C(=O)O.Cl
- CAS データベース
- 86483 · 86483-48-9(CAS DataBase Reference)
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
Danger
H315 (33.3%): Causes skin irritation [Warning Skin corrosion/irritation]
P233, P260, P261, P264, P264+P265, P271, P272, P273, P280, P284, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P391, P403, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 3 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
危険有害性情報
Hazard Classes and CategoriesSkin Irrit. 2 (33.3%)
安全データ
- hs_code
- 29419000
- risk_code
- 36/37/38
- hazard_code
- Xi
- safety_code
- 26-36
化学と産業
薬理情報
MeSH Pharmacological Classification
Substances that inhibit the growth or reproduction of BACTERIA.
Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II.
Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 CYP1A2.
上流・下流製品情報
上流原料
補足説明
定義ChEBI: The anhydrous form of the monohydrochloride salt of ciprofloxacin.
関連反応
5 件
化合物ノート
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