DL-セレノシステイン

The worker should immediately wash the skin when it becomes contaminated. /Selenium/

Work clothing that becomes wet or significantly contaminated should be removed and replaced. /Selenium/

8 hr Time Weighted Avg (TWA): 0.2 mg/cu m. /Selenium & compounds, as Se/

Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded. /Selenium & compounds, as Se/

Wear appropriate personal protective clothing to prevent skin contact. /Selenium/

Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure. (Note: It is intended that these facilities provide a sufficient quantity or flow of water to quickly remove the substance from any body areas likely to be exposed. The actual determination of what constitutes an adequate quick drench facility depends on the specific circumstances. In certain instances, a deluge shower should be readily available, whereas in others, the availability of water from a sink or hose could be considered adequate.) /Selenium/

Recommendations for respirator selection. Max. concn for use: 1 mg/cu m. Respirator Class(es): Any dust and mist respirator. If not present as a fume. May require eye protection. Any dust, mist, and fume respirator. May require eye protection. Any air-purifying, full-facepiece respirator with a high-efficiency particulate filter. Any powered, air-purifying respirator with a dust and mist filter. If not present as a fume. May require eye protection. Any powered, air-purifying respirator with a dust, mist, and fume filter. May require eye protection. Any supplied-air respirator. May require eye protection. Any self-contained breathing apparatus with a full facepiece. /Selenium/

Recommendations for respirator selection. Condition: Emergency or planned entry into unknown concentrations or IDLH conditions: Respirator Class(es): Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive pressure-mode. Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained breathing apparatus operated in pressure-demand or other positive-pressure mode. /Selenium/

Recommendations for respirator selection. Condition: Escape from suddenly occurring respiratory hazards: Respirator Class(es): Any air-purifying, full-facepiece respirator with a high-efficiency particulate filter. Any appropriate escape-type, self-contained breathing apparatus. /Selenium/

The effects of cadmium, mercury (Hg), and three different chemicals forms of selenium (selenite, selenocystine, and selenomethionine) on ram spermatozoal motility and oxygen consumption in vitro were studied over a 4 mo period. Concentrations of 10(-6) to 10(-2) M cadmium and mercury were injurious to spermatozoa as indicated by depressed motility and reduced oxygen uptake. Equimolar concentrations of selenium as selenite, selenocystine, or selenomethionine counteracted the toxicity of cadmium and mercury at low concentrations (10(-5) and 10(-6) M) but not at higher concentrations (10(-4) to 10(-2) M). /Selenocystine/

The chemopreventive efficacies of selenate, selenite, selenium dioxide, selenomethionine and selenocystine were examined during the promotion phase of carcinogenesis in the 7,12-dimethylbenz(a)anthracene-induced mammary tumor model in rats. Each agent was added to the diet of a final concentration of 3 ppm selenium. In general, there was no significant difference in the potency of these five selenium compounds in inhibiting the development of mammary tumors. The interaction of vitamin E (500 ppm) with either selenite or selenomethionine was further characterized in a second carcinogenesis study. Results of this experiment suggested that vitamin E enhanced the protective effect of selenite but not that of selenomethionine. In an attempt to explore the synergistic mechanism of selenium and vitamin E, the effects of these two agents on mitogen induced blastogenesis and natural killer cytotoxic activity were also investigated. No consistent changes in these in vitro immune functions were detected resulting from supranutritional feeding of either selenite or vitamin E or both. ... /Cystine/

D010; A solid waste containing selenium (such as seleno-(dl)-cysteine) may or may not become characterized as a hazardous waste when subjected to the Toxicity Characteristic Leaching Procedure listed in 40 CFR 261.24, and if so characterized, must be managed as a hazardous waste.

Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Seleno-(DL)-cysteine is included on this list.

(AZ) ARIZONA 10 ug/l /Selenium/

(NY) NEW YORK 10 ug/l /Selenium/

(AZ) ARIZONA 45 ug/l /Selenium/

(CT) CONNECTICUT 10 ug/l /Selenium/

(ME) MAINE 10 ug/l /Selenium/

(MN) MINNESOTA 30 ug/l /Selenium/