| 毒性の概要 | IDENTIFICATION AND USE: Methyl chloride is a colorless compressed gas or liquid. Most methyl chloride is used as an intermediate feedstock in silicone fluids, elastomers, and resins. Methyl chloride has been used in timber products processing, as a blowing agent for some polystyrene foams, and as a refrigerant. It was formerly used as an aerosol propellant. As a pesticide, methyl chloride is not registered for current use in the U.S.but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses. HUMAN EXPOSURE AND TOXICITY: The many symptoms of acute exposure include headache, nausea, irritation of the skin and eyes, central nervous system depression, pulmonary edema, hemolysis, chronic intoxication, paresthesia, narcosis, increased risk of spontaneous abortion, intravascular hemolysis, unconsciousness, rapid followed by slow respiration, painful joints, swelling of the extremities, diabetes, aspiration pneumonia, gross hematuria, reduction of blood pH, gastrointestinal injury, upper respiratory tract irritation, depression, fatigue, vertigo, liver damage, blood dyscrasias, acceleration of the pulse, congestion in the head, neurasthenic disorders, digestive disturbances, acoustical and optical delusions, arrhythmias produced by catecholamines, faintness, loss of appetite, hyporeflexia, gross hemoglobinuria, metabolic acidosis, GI hemorrhage, diverticula, kidney damage, lung damage, corneal injury, abdominal pain, increase in salivary gland tumors, cyanosis, convulsions, coma, and death. Deaths have occurred following single severe or repeated prolonged moderate overexposure. Methyl chloride is poisonous intravenouslymoderately toxic by ingestion, subcutaneous, and intraperitoneal routesmildly toxic by inhalation. Most cases of intoxication by methyl chloride have involved concentrations above 500 ppm. After methyl chloride leakage from a refrigerator occurred on board an Icelandic f |
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