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カルボキシメチルセルロースナトリウム

Sodium carboxymethyl cellulose

HCID 6328154
ノート反応
基本情報概要名称と識別子物性安全と法規制化学と産業関連反応化合物ノート
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基本情報

CAS
9004-32-4
標準SMILES
CC(=O)O.O=CC(O)C(O)C(O)C(O)CO.[Na]
InChIKey
DPXJVFZANSGRMM-UHFFFAOYSA-N
分子式
C8H16NaO8
平均分子量
263.2 g/mol

概要

Carboxymethylcellulose sodium salt is an organic molecular entity. It has a role as a food additive.

名称と識別子

優先名称
Sodium carboxymethyl cellulose
現地名
カルボキシメチルセルロースナトリウム
英語名
Sodium carboxymethyl cellulose
分子式
C6H7O2(OH)2CH2COONa
分子量
0

名称と別名

Carboxymethylcellulose sodium salt9004-32-4Carmellose sodiumCarboxymethylcellulose sodiumCarmethoseCellofasCellufreshCellugelCelluviscCollowelEthoxoseCellpro
名称をさらに表示
カルボキシメチルセルロースナトリウム n≒1050カルボキシメチルセルロースナトリウム n≒500セルロースグリコラートナトリウムカルボキシメチルセルロースナトリウム塩ナトリウムカルボキシメチルセルロースセルロースグリコール酸ナトリウム塩カルボキシメチルセルロースナトリウムCMC-ナトリウムセルロースカルボキシメチルエーテルナトリウム塩アクアシド Iアクアシド IIセルロースグリコール酸ナトリウムナトリウムカルボキシメチルセルロスカルメロースNaセルロースガムCMC ナトリウム塩(カルボキシメチルセルロースナトリウム)カルボキシメチルセルロースナトリウム (n=約1,050)カルボキシメチルセルロースナトリウム (n=約500)セルロースグリコール酸ナトリウム (n=約1,050)セルロースグリコール酸ナトリウム (n=約500)CMC-Nacellulose gumb10Carboxyl Methyl Cellulose sodiumcarboColor Specklescmc2AC-DI-SOL

物性

構造計算による物性

極性表面積
156 Ų
水素結合供与体数
6
水素結合受容体数
8
回転可能結合数
5
重原子数
17
形式電荷
0
複雑度
169

実験および物理化学的性質

PolymersBiological Agents -> Polysaccharides
CosmeticsViscosity controlling; Film forming; Binding; Emulsion stabilizing
pHNot less than 5,0 and not more than 8,5 (1 % colloidal solution)
FragrancesFragrance Ingredient (Cellulose, carboxymethyl ether, sodium salt) -> IFRA transparency List
Food AdditivesANTICAKING AGENT OR FREE-FLOW AGENT, DRYING AGENT, EMULSIFIER OR EMULSIFIER SALT, FORMULATION AID, HUMECTANT, STABILIZER OR THICKENER, TEXTURIZER -> FDA Substance added to food
SolubilityYields a viscous colloidal solution with water. Insoluble in ethanol
Food Contact Substances · 2 件

FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR

FCS -> FDA Inventory of Effective Food Contact Substance (FCS) Notifications

Physical Description · 3 件

Dry Powder

Slightly hygroscopic white or slightly yellowish or greyish odourless and tasteless, granular or fibrous powder

White solid; Powdered form is hygroscopic; [Merck Index] White or slightly yellowish hygroscopic solid; Nearly odorless; [JECFA] Beige hygroscopic powder; [Sigma-Aldrich MSDS]

安全と法規制

安全情報は参考情報です。供給元の安全データシート(SDS)、適用法令、専門家による評価に代わるものではありません。

GHS分類

GHS Classification · 3 件

This chemical does not meet GHS hazard criteria for 97.3% (1711 of 1758) of all reports.

Not Classified

Aggregated GHS information provided per 1758 reports by companies from 6 notifications to the ECHA C&L Inventory.

危険有害性情報

Regulatory Information · 5 件

Chemical: Cellulose, carboxymethyl ether, sodium salt

Regulation (EC) No 1831/2003 (amended)

Cellulose, carboxymethyl ether, sodium salt is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Cellulose, carboxymethyl ether, sodium salt are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

FRI - indicates a polymeric substance containing no free-radical initiator in its Inventory name but is considered to cover the designated polymer made with any free-radical initiator regardless of the amount used.

Sodium carboxymethylcellulose: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Cellulose, carboxymethyl ether, sodium salt: Human health tier I assessment
Hazards SummaryCauses changes in liver weight, other changes in urine composition, and changes in sodium in 13-week constant oral studies of rats; [RTECS] May cause irritation; [Sigma-Aldrich MSDS] See Cellulose.
EPA Safer ChemicalChemical: Cellulose, carboxymethyl ether, sodium salt
Hazard Classes and CategoriesNot Classified

毒性情報

化学と産業

薬理情報

MeSH Pharmacological ClassificationAgents that produce a soft formed stool, and relax and loosen the bowels, typically used over a protracted period, to relieve CONSTIPATION.

用途と製造

Uses · 2 件

Used in drilling muds, detergents, resin emulsion paints, adhesives, printing inks, and textile sizes; Also used as a protective colloid, a stabilizer for foods, and a pharmaceutical additive; [Merck Index] Used as a bulk laxative, emulsifier and thickener in cosmetics and pharmaceuticals, and stabilizer for reagents; [ChemIDplus] Formerly registered in the US for use as an insecticide for ornamentals and flowering plants; [NPIRS] Permitted for use as an inert ingredient in non-food pesticide products; [EPA] Used as an anticaking agent, drying agent, emulsifier, formulation aid, humectant, stabilizer or thickener, and texturizer in foods; [FDA]

Petroleum Production and Refining [Category: Industry]

U.S. Production2023: 1,000,000 - <2,500,000 lb
Consumer UsesNot Known or Reasonably Ascertainable
Industry UsesNot Known or Reasonably Ascertainable
Household ProductsInformation on 142 consumer products that contain Sodium Carboxymethyl Cellulose in the following categories is provided:
Use Classification · 6 件

EPA Safer Chemical Functional Use Classes -> Chelating Agents;Processing Aids and Additives

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Food additives

Fragrance Ingredients

Food Additives -> EMULSIFIER; STABILIZER; THICKENER -> JECFA Functional Classes

Food Additives -> EMULSIFIER; STABILIZER; THICKENER -> JECFA Functional Classes

General Manufacturing Information

関連反応

0 件
反応記録を作成

現在のフィルター条件では反応記録がありません。

化合物ノート

読み込み中…

このページの内容基本情報概要名称と識別子物性安全と法規制化学と産業関連反応化合物ノート
Cellex
LovosaSarcell telCellofas BCellofas CCellogel CCellogen PRGlikocel TACMC sodium salt

データベース識別子

CAS
9004-32-4
PubChem CID
6328154
ChEMBL
CHEMBL2109001
ChEBI
CHEBI:234035
EC Number
618-378-6

物理化学的性質

融点
274 °C · 274 °C (dec.)
比重(密度)
1 · 1,6 g/cm3
FEMA
2239 · 2239 | CARBOXYMETHYLCELLULOSE
屈折率
1.515 · 1.515
貯蔵温度
room temp
溶解性
2 O: · H2O: 20 mg/mL、可溶
酸解離定数(Pka)
4.3 · 4.30(at 25℃)
外見
低粘度
色
白色~淡黄色
臭い (Odor)
無臭
PH
pH (10g/l, 25℃) 6.0~8.0
由来生物
wood (pulp)
水溶解度
溶ける
Merck
14 · 14,1829
安定性
安定。強力な酸化剤とは相容れない。
化粧品成分の機能
乳化安定剤香料粘度制御フィルム形成バインディング
InChI
1S/C6H12O6.C2H4O2.Na/c7-1-3(9)5(11)6(12)4(10)2-8;1-2(3)4;/h1,3-6,8-12H,2H2;1H3,(H,3,4);
InChIKey
DPXJVFZANSGRMM-UHFFFAOYSA-N
SMILES
[Na].OC(C(O)C(O)C=O)C(O)CO.OC(=O)C
EPAの化学物質情報
Sodium carboxymethyl cellulose (9004-32-4)

化学的性質

化学的特性Carboxymethylcellulose sodium occurs as a white to almost white, odorless, tasteless, granular powder. It is hygroscopic after drying.

Toxicity Data
LC50 (rat) > 5,800 mg/m3/4hr

安全データ

F
3
wgk
1
tsca
TSCA listed
rtecs
FJ5950000
毒性
LD50 oral in rabbit: > 27gm/kg
hs_code
39123100
risk_code
40
化審法
(8)-203
safety_code
24/25
自然発火温度
698 °F
ストレージクラス
11 - Combustible Solids
· 2 件

Oil and Gas Drilling, Extraction, and Support activities

Cellulose, carboxymethyl ether, sodium salt: ACTIVE

応用分野 · 3 件

用途乳化剤、安定剤、増粘剤。

使用In drilling muds, in detergents as a soil-suspending agent, in resin emulsion paints, adhesives, printing inks, textile sizes, as protective colloid in general. As stabilizer in foods. Pharmaceutic aid (suspending agent; tablet excipient; viscosity-increasing agent).

一般的な説明Sodium carboxymethyl cellulose (CMC) belongs to the class of anionic linear structured cellulose. Its components consist of polysaccharide composed of fibrous tissues of plants. It is a water soluble polymer which can be used as a polyelectrolyte cellulose derivative.

調製方法 · 2 件

Alkali cellulose is prepared by steeping cellulose obtained from wood pulp or cotton fibers in sodium hydroxide solution. The alkaline cellulose is then reacted with sodium monochloroacetate to produce carboxymethylcellulose sodium. Sodium chloride and sodium glycolate are obtained as by-products of this etherification.

純化方法Dialyse it for 48hours against distilled water and freeze-dry if a solid is required.

上流・下流製品情報

上流原料

Acetateアルカリセルロースエタノールクロロ酢酸Defatted cottonセルロース(紙繊維)酢酸水酸化ナトリウムKneaderSolid chlorineキチンクロロ酢酸ナトリウム

下流製品

アドレノコルチコトロピンdrug delivery of chitosan carboxymethylcellulose complexesSOD anti-decrepitude healthy toothpastenerves calming toothpasteカルボキシメチルセルロースカルシウムpearly toothpaste

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補足説明 · 2 件

定義本品は、セルロース(*)のカルボキシメチルエーテルのナトリウム塩である。参照表示名称:セルロース

定義A semisynthetic, water-soluble polymer in which CH 2 COOH groups are substituted on the glucose units of the cellulose chain through an ether link- age. Mw ranges from 21,000 to 500,000. Since the reaction occurs in an alkaline medium, the prod- uct is the sodium salt of the carboxylic acid R-O- CH 2 COONa.