Cobalt oxide

HCID 6432046CAS 11104-61-3

基本情報

標準SMILES: [Co+2].[Co+3].[Co+3].[O-2].[O-2].[O-2].[O-2]
InChIKey: UBEWDCMIDFGDOO-UHFFFAOYSA-N
分子式: Co3O4
平均分子量: 240.797 g/mol
単同位体質量: 240.77924

名称と識別子

優先名称: Cobalt oxide
IUPAC: cobalt(2+);bis(cobalt(3+));tetrakis(oxygen(2-))
英語名: Cobalt oxide
分子式: CoO
分子量: 0

名称と別名

Cobalt tetraoxideUSK772NS5611104-61-3234-334-5Co(3)O(4)Cobalt oxideCobaltum OxydatumDTXSID801014561RefChem:58007Tricobalt tetraoxideCobaltic-cobaltous oxidecobalt(2+);cobalt(3+);oxygen(2-)

名称をさらに表示

cobalt(2+),oxygen(2-)cobalt(2+),oxygen(2 oxygen(2-)

Cobalt oxide blackCOBALT (II,III) OXIDEoxocobalt; oxo(oxocobaltiooxy)cobaltEINECS 215-157-2Cobalt (II, III) oxideUNII-USK772NS56COBALT OXIDE [MART.]SCHEMBL5054762

データベース識別子

CAS: 11104-61-3、1308-06-1
PubChem CID: 6432046
UNII: USK772NS56
EC Number: 215-157-2、234-334-5

物性

構造計算による物性

極性表面積: 4 Å²
水素結合供与体数: 0
水素結合受容体数: 4
回転可能結合数: 0
重原子数: 7
形式電荷: 0
複雑度: 0

実験および物理化学的性質

Physical Description · 2 件

Large Crystals; Dry Powder

Black or grey solid; [Merck Index] Black powder, insoluble in water; [MSDSonline]

物理化学的性質

EPAの化学物質情報: Cobalt oxide (11104-61-3)

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 100% (7 of 7) of all reports.

Not Classified；Reported as not meeting GHS hazard criteria by 7 of 7 companies. For more detailed information, please visit ECHA C&L website.

Aggregated GHS information provided per 7 reports by companies from 1 notifications to the ECHA C&L Inventory.；Reported as not meeting GHS hazard criteria per 7 of 7 reports by companies.；There are 0 notifications provided by 0 of 7 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Danger

H317: May cause an allergic skin reaction [Warning Sensitization, Skin]；H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]；H372: Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]

危険有害性情報

Regulatory Information · 4 件

Chemical: Cobalt oxide

Cobalt oxide is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Cobalt oxide are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 21-04-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15110

Cobalt oxide: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Cobalt oxide: Human health tier II assessment

Hazards SummaryHarmful if swallowed; May cause skin sensitization; [MSDSonline] See Cobalt.

Hazard Classes and Categories · 3 件

Not Classified

Specific target organ toxicity (repeated exposure) - category 1；Reproductive toxicity - category 1B；Respiratory sensitisation - category 1；Skin sensitisation - category 1；Acute toxicity (ingestion) - category 3；Acute toxicity (inhalation) - category 2

Respiratory sensitization - Category 1A；Skin sensitization - Category 1A；Specific target organ toxicity - Repeated exposure - Category 1 (respiratory organs)

安全と保護具

Exposure Control and Personal ProtectionBiological Exposure Indices (BEI) [ACGIH] - Cobalt in urine = 15 ug/L; sample at end of shift at end of workweek;

Minimum Risk LevelChronic Inhalation: 0.0001 mg/m3 (L134) Intermediate Oral: 0.01 mg/kg/day (L134)

Threshold Limit Values (TLV)0.02 [mg/m3], as Co

Protective Action Criteria (PAC) · 3 件

0.082 [mg/m3]

6.7 [mg/m3]

40 [mg/m3]

毒性情報

TreatmentTreatment of cobalt poisoning is symptomatic. (L29)

Health EffectsExposure to high amount of cobalt can cause heart, lung, kidney, and liver damage. Skin contact is known to result in contact dermatitis. Cobalt may also have mutagenic and carcinogenic effects. (L29, L30)

Adverse EffectsSkin Sensitizer - An agent that can induce an allergic reaction in the skin.；Fibrogenic - Inducing tissue injury and fibrosis (scarring).

Exposure RoutesInhalation (L29) ; oral (L29) ; dermal (L29)

Toxicity Summary · 1 件

Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, causing increased lipid peroxidation, DNA damage, and inducing certain enzymes that lead to cell apoptosis. Cobalt has also been shown to block inorganic calcium channels, possibly impairing neurotransmission. Cobalt can also chelate lipoic acids, impairing oxidation of pyruvate or fatty acids. In addition, cobalt may inhibit DNA repair by interacting with zinc finger DNA repair proteins, and has also been shown to inhibit heme synthesis and glucose metabolism. Cobalt may activate specific helper T-lymphocyte cells and interact directly with immunologic proteins, such as antibodies (IgA and IgE) or Fc receptors, resulting in immunosensitization. (L29)

Signs and SymptomsCobalt inhalation can cause asthma-like breathing problems. Skin contact is known to result in contact dermatitis, which is characterized by irritation and rashes. Ingesting large amounts of cobalt may cause nausea and vomiting. (L2090)

法規制情報

Regulatory Information · 4 件

Chemical: Cobalt oxide

Status: Active Update: 21-04-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15110

Cobalt oxide: Does not have an individual approval but may be used under an appropriate group standard

安全データ

tsca: TSCA listed

化学と産業

薬理情報

Metabolism/Metabolites · 1 件

Cobalt is absorbed though the lungs, gastrointestinal tract, and skin. Since it is a component of the vitamin B12 (cyanocobalamin), it is distributed to most tissues of the body. It is transported in the blood, often bound to albumin, with the highest levels being found in the liver and kidney. Cobalt is excreted mainly in the urine and faeces. (L29)

用途と製造

Uses · 4 件

Used in enamels, semiconductors, and grinding wheels; [Merck Index] When cobalt (II) oxide is heated at 400-500 deg C in an atmosphere of oxygen, the cobalt (II,III) oxide is formed. [Ullmann]

Semiconductor Manufacturing [Category: Industry]

Enameling [Category: Hobbies]

No data.

U.S. Production2023: 468,662 lb；2022: 296,710 lb；2021: 359,860 lb；2020: 366,399 lb

Consumer UsesOther

Industry UsesOther

General Manufacturing Information · 2 件

Petroleum Refineries；Primary Metal Manufacturing

Cobalt oxide: ACTIVE