Aluminum Phosphate

Metals -> Phosphates, Metallic Salts

Corrosives

2.56 g/cm³

2.56 @25 °C

>1500 °C

1800 °C

Aluminum phosphate, solution appears as a colorless liquid. Insoluble in water. Corrosive to metals and tissue.

Other Solid; Dry Powder; Large Crystals

White solid; [Merck Index] Beige powder; [Sigma-Aldrich MSDS]

WHITE CRYSTALLINE POWDER.

This chemical does not meet GHS hazard criteria for 54.6% (352 of 645) of all reports.

Danger

H314 (16.3%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P261, P264, P264+P265, P271, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P319, P321, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 645 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Chemical: Phosphoric acid, aluminium salt (1:1)

Phosphoric acid, aluminum salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phosphoric acid, aluminum salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 21-09-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/15223

Aluminium phosphate, basic: Does not have an individual approval but may be used under an appropriate group standard

Aluminium phosphate: Does not have an individual approval but may be used under an appropriate group standard

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

Not combustible.

A - Alimentary tract and metabolism

QA - Alimentary tract and metabolism

Used as an adjuvant in vaccines, the precise mechanism of action of aluminum phosphate (and other aluminum salts) is not well-defined. Broadly speaking, aluminum salts and other vaccine adjuvants are intended to bolster the immune response at the site of administration, thereby conferring greater immunity. Colloidal aluminum phosphate used as an antacid works by neutralizing stomach acid following administration.

Aluminum is poorly absorbed following either oral or inhalation exposure and is essentially not absorbed dermally. The bioavailability of aluminum is strongly influenced by the aluminum compound and the presence of dietary constituents which can complex with aluminum and enhance or inhibit its absorption. Aluminum binds to various ligands in the blood and distributes to every organ, with highest concentrations found in bone and lung tissues. In living organisms, aluminum is believed to exist in four different forms: as free ions, as low-molecular-weight complexes, as physically bound macromolecular complexes, and as covalently bound macromolecular complexes. Absorbed aluminum is excreted principally in the urine and, to a lesser extent, in the bile, while unabsorbed aluminum is excreted in the faeces. (L739)

Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.

Substances that counteract or neutralize acidity of the GASTROINTESTINAL TRACT.