基本情報
- 標準SMILES
CN[C@@H](C)[C@H](O)c1ccccc1.Cl- InChIKey
BALXUFOVQVENIU-GNAZCLTHSA-N- 分子式
- C10H16ClNO
- 平均分子量
- 201.69 g/mol
- 単同位体質量
- 201.09204181
概要
Ephedrine hydrochloride is an alkylbenzene.
名称と識別子
- 優先名称
- Ephedrine Hydrochloride
- IUPAC
- (1R,2S)-2-(methylamino)-1-phenylpropan-1-ol;hydrochloride
名称と別名
Ephedrine hydrochloride50-98-6(-)-Ephedrine hydrochlorideL-Ephedrine hydrochlorideEPHEDRINE HCLDTXSID1045825REZIPRESNLJ6390P1ZEphedrini hydrochloridumNSC-759611DTXCID9025825Benzenemethanol, alpha-(1-(methylamino)ethyl)-, hydrochloride, (R-(R*,S*))-
名称をさらに表示
Benzenemethanol, alpha-((1S)-1-(methylamino)ethyl)-, hydrochloride, (alphaR)-BronchipaxTaumasthmanAsmapaxExpurhinTabasanSecronEphed hcl
データベース識別子
- CAS
50-98-6- PubChem CID
- 65326
- DTXSID
DTXSID1045825- ChEMBL
CHEMBL2146102- ChEBI
CHEBI:31541- UNII
- NLJ6390P1Z
- EC Number
- 200-074-6
物性
構造計算による物性
- 極性表面積
- 32.3 Ų
- 水素結合供与体数
- 3
- 水素結合受容体数
- 2
- 回転可能結合数
- 3
- 重原子数
- 13
- 形式電荷
- 0
- 複雑度
- 121
実験および物理化学的性質
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
安全と法規制
GHS分類
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 114 reports by companies from 7 notifications to the ECHA C&L Inventory.
危険有害性情報
Regulatory Information
Status: Active Update: 08-11-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/10058
Ephedrine hydrochloride: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Benzenemethanol, .alpha.-[1-(methylamino)ethyl]-, hydrochloride, [R-(R*,S*)]-: Environment tier I assessment
Hazard Classes and CategoriesAcute Tox. 4 (100%)
化学と産業
薬理情報
FDA Pharmacological Classification
EPHEDRINE HYDROCHLORIDE
Increased Norepinephrine Activity [PE]; Norepinephrine Releasing Agent [EPC]; Adrenergic beta-Agonists [MoA]; Adrenergic alpha-Agonists [MoA]; alpha-Adrenergic Agonist [EPC]; beta-Adrenergic Agonist [EPC]
MeSH Pharmacological Classification
A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here.
Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
Drugs used to cause constriction of the blood vessels.
Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters.
用途と製造
General Manufacturing InformationBenzenemethanol, .alpha.-[(1S)-1-(methylamino)ethyl]-, hydrochloride (1:1), (.alpha.R)-: ACTIVE
関連反応
6 件
関連ノート
読み込み中…