N-メチル-N-ニトロソ-p-トルエンスルホンアミド

Diazald

HCID 6628CAS 60858-95-9
部分構造検索類似構造を探す

基本情報

標準SMILES
Cc1ccc(S(=O)(=O)N(C)N=O)cc1
InChIKey
FFKZOUIEAHOBHW-UHFFFAOYSA-N
分子式
C8H10N2O3S
平均分子量
214.24 g/mol
単同位体質量
214.04121336

名称と識別子

優先名称
Diazald
IUPAC
N,4-dimethyl-N-nitrosobenzenesulfonamide
現地名
N-メチル-N-ニトロソ-p-トルエンスルホンアミド
英語名
N-Methyl-N-nitrosotoluene-4-sulphonamide
分子式
C8H10N2O3S
分子量
214.24

名称と別名

DiazaldDiazaloN-nitroso-N-methyl-4-toluenesulfonamideRefChem:85825380-11-5N-Methyl-N-nitroso-p-toluenesulfonamideN-Methyl-N-nitrosotoluene-4-sulphonamideN,4-dimethyl-N-nitrosobenzenesulfonamideDiazaleP-TOLYLSULFONYLMETHYLNITROSAMIDEBenzenesulfonamide, N,4-dimethyl-N-nitroso-p-Toluenesulfonamide, N-methyl-N-nitroso-
名称をさらに表示
N-メチル-N-ニトロソ-p-トルエンスルホンアミドジアザルドN-ニトロソ-N-メチル-p-トルエンスルホンアミドN,4-ジメチル-N-ニトロソベンゼンスルホンアミドN-メチル-N-ニトロソ-4-メチルベンゼンスルホンアミドN-ニトロソ-N-メチル-4-メチルベンゼンスルホンアミドメチル(4-メチルフェニルスルホニル)ニトロソアミンp-トリルスルホニルメチルニトロソアミド4,N-ジメチル-N-ニトロソベンゼンスルホンアミドN-ニトロソ-N,4-ジメチルベンゼンスルホンアミドp-トルエンスルホニル-N-メチル-N-ニトロソアミドN‐メチル‐N‐ニトロソ‐P‐トルエンスルホンアミドN-メチル-N-ニトロソ-P-トルエンスルホンアミド P-トルエンスルホニル-N-メチル-N-ニトロソアミドｐ-トリルスルホメチルニトロソアミドN,4-dimethyl-N-nitroso-BenzenesulfonamideDIAZOGENN-Methyl-N-nitroso-4-toluenesulfonamideDIAZALD(R)Diazogen,99%Diazogen,95%
p-TolylsulfonylmethylnitrosamineMethylnitroso-p-toluenesulfonamideToluene-p-sulfonylmethylnitrosamideN-Nitroso-N-methyl-p-toluenesulfamideN-Nitroso-N-methyl-4-tolylsulfonamideN-Methyl-N-nitroso-p-tolylsulfonylamidep-Tolylsulfonyl-methyl-nitrosamidNSC 313

データベース識別子

CAS
60858-95-9、80-11-5
PubChem CID
6628
DTXSID
DTXSID8058827
ChEMBL
CHEMBL1606452
ChEBI
CHEBI:143725
UNII
K3089966LA
EC Number
201-252-6、693-083-3
Nikkaji
J3.851B

物性

構造計算による物性

XLogP
0.6
極性表面積
75.2 Ų
水素結合供与体数
0
水素結合受容体数
5
回転可能結合数
2
重原子数
14

実験および物理化学的性質

Color/FormYELLOW CRYSTALS FROM BENZENE + PETROLEUM ETHER
Solubility · 4 件

INSOL IN WATER; SOL IN ETHER, PETROLEUM ETHER, BENZENE

SOL IN CHLOROFORM, CARBON TETRACHLORIDE

VERY SOL IN HOT ALC

SOL IN MOST ORGANIC SOLVENTS

Melting Point62 °C
Vapor Pressure0.00000479 [mmHg]
Physical DescriptionYellow solid; [Merck Index] Fine light yellow crystals; [MSDSonline]
Stability/Shelf LifeSTABLE IN ORDINARY BROWN BOTTLE FOR SEVERAL YR; WHITE COATING (FORMED OF P-TOLYLSULFONYLMETHYLAMIDE) DOES NO HARM

物理化学的性質

融点
58 °C · ~58 °C
沸点
320.5 · 320.5±35.0 °C(Predicted)
比重(密度)
1.3844 · 1.3844 (rough estimate)
屈折率
1.569 · 1.5690 (estimate)
貯蔵温度
2 · 2-8°C
溶解性
Chloroform (Slightly), Dichloromethane (Sparingly), DMSO (Slightly), Ethyl Acetate

化学的性質

化学的特性pale yellow crystalline powder

安全と法規制

GHS分類

GHS Classification · 6 件

Danger

H242 (90.9%): Heating may cause a fire [Danger Self-reactive substances and mixtures; Organic peroxides]；H315 (97.7%): Causes skin irritation [Warning Skin corrosion/irritation]；H317 (88.6%): May cause an allergic skin reaction [Warning Sensitization, Skin]；H319 (97.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (88.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P210, P234, P235, P240, P261, P264, P264+P265, P271, P272, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P370+P378, P403, P403+P233, P405, P410, P411, P420, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 44 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory InformationBenzenesulfonamide, N,4-dimethyl-N-nitroso-: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryA mutagen and tumorigen; [RTECS] May explode from shock or friction; May polymerize; An irritant; May cause skin sensitization; [MSDSonline]
Hazard Classes and Categories · 2 件

Self-react. C (90.9%)；Skin Irrit. 2 (97.7%)；Skin Sens. 1 (88.6%)；Eye Irrit. 2 (97.7%)；STOT SE 3 (88.6%)

Skin Irrit. 2 (100%)；Skin Sens. 1 (100%)；Eye Irrit. 2 (100%)；STOT SE 3 (100%)

法規制情報

Regulatory InformationBenzenesulfonamide, N,4-dimethyl-N-nitroso-: Does not have an individual approval but may be used under an appropriate group standard

安全データ

wgk
2
tsca
TSCA listed
rtecs
XT5950000
ridadr
UN 3234 4.1/PG 2
hs_code
29350090
risk_code
2-36/37/38-43-20/21/22

化学と産業

用途と製造

Uses · 2 件

Used to make diazomethane in the laboratory; [Merck Index]

IN LAB PREPN OF DIAZOMETHANE

Methods of ManufacturingPREPD BY ACTION OF NITROUS ACID ON P-TOLYLSULFONYLMETHYLAMIDE: GERMAN PATENT 224,388 (1910 TO BAYER)...
Formulations/PreparationsDIAZALD. TRADEMARK FOR N-METHYL-N-NITROSOPARATOLUENESULFONAMIDE.
General Manufacturing InformationBenzenesulfonamide, N,4-dimethyl-N-nitroso-: ACTIVE

応用分野

解説N,4-dimethyl-N-nitrosobenzenesulfonamide．C8H10N2O3S(214.25)．N-メチル-N-ニトロソ-p-トルエンスルホンアミド, p-トルエンスルホニルクロリドとメチルアミンとからN-メチルアミドを合成し，それをニトロソ化すると得られる．黄色の結晶．融点62 ℃．アルカリを作用させてジアゾメタンの発生に用いる．比較的安定で室温で保存可能である．森北出版「化学辞典（第2版）

使用N-Methyl-N-nitroso-p-toluenesulfonamide is Diazomethane precursor.

調製方法 · 1 件

純化方法Crystallise diazald from *benzene by addition of pet ether and store it in a refrigerator. It is soluble in most organic solvents and liberates diazomethane on treatment with alkali. Store it in the cold. [deBoer & Backer Org Synth 34 96 1954, Beilstein 11 I 29.]

上流・下流製品情報

サプライヤー50 社

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南京兰亚化工贸易有限公司+86-25-8331-5620 · [email protected]
衢州明锋化工有限公司0570-3062502 13819002126;13819008176 · [email protected]

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