2,2-dimethylmalonic acid 5-{(R)-(4-{amino(2,2-dimethylpropoxycarbonylimino)methyl}phenylamino)-[2-fluoro-3-(2-hydroxyethoxy)-5-methoxyphenyl]methyl}-2-pyrimidin-2-yl-2H-[1,2,4]-triazol-3-yloxymethyl ester isopropyl ester (HCID 67470487)

基本情報

標準SMILES: COc1cc(OCCO)c(F)c([C@@H](Nc2ccc(C(N)=NC(=O)OCC(C)(C)C)cc2)c2nc(OCOC(=O)C(C)(C)C(=O)OC(C)C)n(-c3ncccn3)n2)c1
InChIKey: KTLAZDWYWPWHNC-GDLZYMKVSA-N
分子式: C38H47FN8O10
平均分子量: 794.8 g/mol
単同位体質量: 794.33991789

名称と識別子

優先名称: 2,2-dimethylmalonic acid 5-{(R)-(4-{amino(2,2-dimethylpropoxycarbonylimino)methyl}phenylamino)-[2-fluoro-3-(2-hydroxyethoxy)-5-methoxyphenyl]methyl}-2-pyrimidin-2-yl-2H-[1,2,4]-triazol-3-yloxymethyl ester isopropyl ester
IUPAC: 1-O-[[5-[(R)-[4-[N'-(2,2-dimethylpropoxycarbonyl)carbamimidoyl]anilino]-[2-fluoro-3-(2-hydroxyethoxy)-5-methoxyphenyl]methyl]-2-pyrimidin-2-yl-1,2,4-triazol-3-yl]oxymethyl] 3-O-propan-2-yl 2,2-dimethylpropanedioate

名称と別名

KTLAZDWYWPWHNC-GDLZYMKVSA-N2,2-dimethylmalonic acid 5-{(R)-(4-{amino(2,2-dimethylpropoxycarbonylimino)methyl}phenylamino)-[2-fluoro-3-(2-hydroxyethoxy)-5-methoxyphenyl]methyl}-2-pyrimidin-2-yl-2H-[1,2,4]-triazol-3-yloxymethyl ester isopropyl ester

データベース識別子

PubChem CID: 67470487

物性

構造計算による物性

XLogP: 6.5
極性表面積: 234 Å²
水素結合供与体数: 3
水素結合受容体数: 16
回転可能結合数: 21
重原子数: 57
形式電荷: 0
複雑度: 1,320

化合物ノート

読み込み中…