トリフルオロアセトアミド

Trifluoroacetamide

HCID 67717CAS 354-38-1
部分構造検索類似構造を探す

基本情報

標準SMILES
NC(=O)C(F)(F)F
InChIKey
NRKYWOKHZRQRJR-UHFFFAOYSA-N
分子式
C2H2F3NO
平均分子量
113.04 g/mol
単同位体質量
113.00884834

名称と識別子

優先名称
Trifluoroacetamide
IUPAC
2,2,2-trifluoroacetamide
現地名
トリフルオロアセトアミド
英語名
Trifluoroacetamide
分子式
C2H2F3NO
分子量
113.04

名称と別名

Trifluoroacetamide2,2,2-Trifluoroacetamide354-38-1Acetamide, 2,2,2-trifluoro-36MU16BYFKNSC-9449DTXSID1059868RefChem:191574DTXCID0039011206-559-9N-trifluoroacetamideC2H2F3NO
名称をさらに表示
トリフルオロアセトアミドα,α,α-トリフルオロアセトアミド2,2,2-トリフルオロアセトアミド2，2，2トリフルオロアセタミドCF3CONH2Triflouroacetamide2-TriflouroacetaMide2,2,4-TrifluoroacetamideThree-Three fluoroacetaMide
MFCD00008008trifluroacetamidetrifluoroacetic acid amidetrifluoro-acetamideNSC 9449BDBM50226184AKOS005207149T0598

データベース識別子

CAS
354-38-1
PubChem CID
67717
DTXSID
DTXSID1059868
ChEMBL
CHEMBL117012
UNII
36MU16BYFK
EC Number
206-559-9
Nikkaji
J157.866I

物性

構造計算による物性

XLogP
0.1
極性表面積
43.1 Ų
水素結合供与体数
1
水素結合受容体数
4
回転可能結合数
0
重原子数
7

実験および物理化学的性質

Chemical ClassesNitrogen Compounds -> Other Nitrogen Compounds
PFAS · 3 件

PFAS -> PFAS identified in REACH Regulation EC No. 1272/2008

PFAS -> Suspected persistent, mobile, toxic (PMT) PFAS or PFAS-like compounds

PFAS

SpringerMaterials PropertiesSchoenflies notation
LogP0.12
Vapor Pressure1.85 [mmHg]
Physical DescriptionWhite to light yellow crystalline powder with a slight ether-like odor; [Acros Organics MSDS]

物理化学的性質

融点
65 · 65-70 °C (lit.)
沸点
162.5 °C · 162.5 °C (lit.)
比重(密度)
1.4176 · 1.4176 (estimate)
闪点
162 · 162-164°C
貯蔵温度
30 °C · Store below +30°C.
溶解性
460 g/L · 460g/L(20℃)

化学的性質

化学的特性white to pale yellow or beige crystalline powder

安全と法規制

GHS分類

GHS Classification · 4 件

Warning

H302 (27.8%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 151 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Regulatory Information · 2 件

Status: Active Update: 08-03-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/12379

2,2,2-Trifluoroacetamide: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryA skin and strong eye irritant; Harmful by ingestion; [ECHA REACH Registrations] An irritant; [Acros Organics MSDS] See Chloroacetamide and Fluoroacetamide.
Hazard Classes and CategoriesAcute Tox. 4 (27.8%)

安全データ

wgk
3
tsca
TSCA listed
ridadr
1759
hs_code
29241900
risk_code
36/37/38
化審法
(2)-3531

化学と産業

用途と製造

UsesUsed as an intermediate in fine chemical manufacture and in scientific research and development; [ECHA REACH Registrations]
General Manufacturing InformationAcetamide, 2,2,2-trifluoro-: ACTIVE
応用分野 · 2 件

使用2,2,2-Trifluoroacetamide used in a convenient alternative to the Gabriel synthesis of primary amines from halides by N-alkylation followed by cleavage of the readily-hydrolyzed trifluoroacetyl group and for improved N-alkylation under phase-transfer conditions allowing successive alkylation with different alkyl groups.

一般的な説明Trifluoroacetamide is a good quencher of tryptophan fluorescence.

上流・下流製品情報

サプライヤー50 社

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
济南万兴达新材料科技有限公司0531-88064106 18253116016 · [email protected]

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