基本情報
- 標準SMILES
O=c1n(Cl)c(=O)n(Cl)c(=O)n1Cl- InChIKey
YRIZYWQGELRKNT-UHFFFAOYSA-N- 分子式
- C3Cl3N3O3
- 平均分子量
- 232.41 g/mol
- 単同位体質量
- 230.9005239
概要
Trichloro-s-triazinetrione, dry appears as a white slightly hygroscopic crystalline powder or lump solid with a mild chlorine-like odor. Said to have 85 percent available chlorine. Decomposes at 225 °C. Moderately toxic by ingestion. May irritate skin and eyes. Active ingredient in household dry bleaches. Used in swimming pools as a disinfectant.
名称と識別子
- 優先名称
- Trichloroisocyanuric Acid
- IUPAC
- 1,3,5-trichloro-1,3,5-triazinane-2,4,6-trione
- 現地名
- トリクロロイソシアヌル酸
- 英語名
- Trichloroisocyanuric acid
- 分子式
- C3Cl3N3O3
- 分子量
- 232.41
名称と別名
名称をさらに表示
データベース識別子
- CAS
87-90-1- PubChem CID
- 6909
- DTXSID
DTXSID2026523- ChEMBL
CHEMBL1698868- ChEBI
CHEBI:33015- UNII
- RL3HK1I66B
- EC Number
- 201-782-8
- Nikkaji
- J4.283H
物性
構造計算による物性
- XLogP
- 1.2
- 極性表面積
- 60.9 Ų
- 水素結合供与体数
- 0
- 水素結合受容体数
- 3
- 回転可能結合数
- 0
- 重原子数
- 12
- 形式電荷
- 0
- 複雑度
- 202
実験および物理化学的性質
Chemical Classes
Other Uses -> Biocides/Disinfectants
Reactive agents - 2nd degree
Density
greater than 1 at 68 °F (est) (USCG, 1999)
Greater than 1 at 20 °C (solid)
2.07 g/cm³
> 1
Color/Form
Needles from ethylene chloride
White crystalline powder or granules
White crystals
Solubility
Soluble in chlorinated and highly polar solvents
Solubility in water at 25 °C = 1 g/100 g; Solubility in acetone at 30 °C = 35.0 g/100 g
Water solubility = 1.2% = 1.20X10+4 mg/L at 25 °C
Solubility in water, g/100ml at 25 °C: 1.2
Decomposition
When heated to decomposition it emits very toxic fumes of /chlorine and nitrogen oxides/.
>225 °C
Melting Point
246.7 °C (decomposes)
235 °C
Vapor Pressure
0.00000012 [mmHg]
negligible
物理化学的性質
- 融点
- 249 · 249-251 °C (lit.)
- 沸点
- 272.3 · 272.3±23.0 °C(Predicted)
- 比重(密度)
- 2.07 · 2.07
- 蒸気圧
- 0.001 · 0.001-0.002Pa at 20-25℃
- 闪点
- 121 °C · 121°C
- 貯蔵温度
- 30 °C · Store below +30°C.
- 溶解性
- クロロホルム(少量、加温)、DMSO(少量)
- 酸解離定数(Pka)
- -4.49 · -4.49±0.20(Predicted)
- 外見
- 粉末または顆粒
- 色
- 白~ほぼ白
- 臭い (Odor)
- 塩素臭
- PH
- 2 · 2.0-2.7 (10g/l, H2O, 20℃)
- 水溶解度
- 1.2 g/100mL · 1.2g/100mL(25℃)
- Merck
- 14 · 14,9641
- BRN
- 202022 · 202022
- Henry's Law Constant
- 1.6 · 1.6×105 mol/(m3Pa) at 25℃, HSDB (2015)
- 安定性
- 安定。湿気、濡れると分解することがあります。可燃物に触れると、火災の原因となることがあります。酸、還元剤、水、強力な酸化剤とは混和しません。
- InChI
- 1S/C3Cl3N3O3/c4-7-1(10)8(5)3(12)9(6)2(7)11
- InChIKey
- YRIZYWQGELRKNT-UHFFFAOYSA-N
- SMILES
- ClN1C(=O)N(Cl)C(=O)N(Cl)C1=O
- LogP
- -1.31 · -1.31-0.94 at 25℃
- CAS データベース
- 87 · 87-90-1(CAS DataBase Reference)
- NISTの化学物質情報
- Trichlorocyanuric acid(87-90-1)
- EPAの化学物質情報
- Trichloro-s-triazinetrione (87-90-1)
化学的性質
化学的特性white to light yellow crystal powde
安全と法規制
GHS分類
GHS Classification
Danger
H272: May intensify fire; oxidizer [Danger Oxidizing liquids; Oxidizing solids]
P210, P220, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P304+P340, P305+P351+P338, P319, P330, P337+P317, P370+P378, P391, P403+P233, P405, and P501 (click each P-code to see the statement)
Danger
H272 (100%): May intensify fire; oxidizer [Danger Oxidizing liquids; Oxidizing solids]
P210, P220, P260, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P319, P321, P330, P337+P317, P363, P370+P378, P391, P403+P233, P405, and P501 (click each P-code to see the statement)
危険有害性情報
Regulatory Information
Chemical: 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-trichloro-
1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-trichloro- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-trichloro- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Status: Active Update: 15-08-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/24502
1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-trichloro-: HSNO Approval: HSR001359 Approved with controls
The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
Fire Hazards
Special Hazards of Combustion Products: Toxic chlorine or nitrogen trichloride may be formed in fires.
CAUTION: Ammonium nitrate products may explode if involved in fire or contaminated with hydrocarbons (fuels), organic matter, other contaminants or when hot molten and contained. Treat as an explosive (GUIDE 112).
Not combustible but enhances combustion of other substances. Gives off irritating or toxic fumes (or gases) in a fire. Risk of explosion on heating. Risk of explosion on contact with combustible substances or incompatible substances. See Chemical Dangers.
Fire Potential
Noncombustible, but due to high reactivity (chlorination, oxidation), may cause ignition by contact with many substances, organic substances easily chlorinated or oxidizeD.
Not combustible. Reacts with combustible materials, ammonium salts, or foreign substances, resulting in fire.
Health Hazards
Inhalation causes sneezing and coughing. Contact with dust causes moderate irritation of eyes and itching and redness of skin. Ingestion causes burns of mouth and stomach. (USCG, 1999)
· Inhalation, ingestion or contact (skin, eyes) with vapors or substance may cause severe injury, burns or death.
Hazards Summary
Forms hypochlorous acid on contact with water; A moderate skin, eye, and mucous membrane irritant; [Merck Index] A strong oxidant that reacts violently with combustible substances; Decomposed by water forming hypochloric acid and cyanuric acid; A mild skin irritant; A severe eye and respiratory tract irritant; Inhalation of dust or decomposition products may cause pulmonary edema; [ICSC] Irritating to skin, eyes, and respiratory tract; Estimated lethal oral dose = 1 ounce to 1 pint for a 150 lb. person; Oral LD50 (rat) = 406 mg/kg; Skin LD50 (rabbit) = 20,000 mg/kg; [HSDB] A strong oxidizing agent; May react with water producing chlorine gas; May cause skin and eye irritation; [CAMEO] A skin, eye, and respiratory tract irritant; May cause corrosive injuries on prolonged contact with skin and eyes; [CHEMINFO] A skin irritant; Corrosive to eyes; [eChemPortal: ERMA] An eye and respiratory tract irritant; [eChemPortal: ESIS] An oxidizing agent; May cause fire on contact with combustible material; An irritant; May cause corrosive injuries; [MSDSonline] See Sodium cyanurate and Sodium dichloroisocyanurate.
Special Reports
European Commission, ESIS; IUCLID Dataset, Symclosene (87-90-1) (2000 CD-ROM edition) contains information on use, toxicology, and environmental effects of this chemical as supplied to the European Union by industry..[Available from, as of September 25, 2009: http://esis.jrc.ec.europa.eu/]
USEPA/Office of Pesticide Programs; Reregistration Eligibility Decision Document - Chlorinated Isocyanurates (September 1992). The RED summarizes the risk assessment conclusions and outlines any risk reduction measures necessary for the pesticide to continue to be registered in the U.S.[Available from, as of October 7, 2009: http://www.epa.gov/pesticides/reregistration/status.htm]
安全と保護具
Fire Fighting
Fire Extinguishing Agents: Water in large amounts (USCG, 1999)
Use water in large amounts, foam, dry powder. In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water.
First Aid Measures
Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again.
Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer immediately for medical attention.
Rinse mouth. Give one or two glasses of water to drink. Do NOT induce vomiting. Refer for medical attention .
Accidental Release Measures
· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.
· Keep combustibles (wood, paper, oil, etc.) away from spilled material.
First Aid
INHALATION: remove victim to fresh air.
General First Aid:
Fire Fighting Procedures
Approach fire from upwind to avoid hazardous vapors and toxic decomposition products. Fight fire from protected location or maximum possible distance. Use flooding quantities of water on fire-involved containers. If necessary use water spray to keep fire-exposed containers cool. Avoid use of water on non-involved material wherever possible.
If material involved in fire: Cool all affected containers with flooding quantities of water. Use water in flooding quantities as fog. Apply water from as far a distance as possible. Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.)
Storage Conditions
Store in a cool, dry, well-ventilated location. Outside or detached storage is preferred. Must be stored in a dry location on pallets arranged according to NFPA 430, Code for Storage of Liquids and Solid Oxidizers. Separate from combustibles, oxidizables, ammonia, sodium carbonate (soda ash), calcium hypochlorite, hydrogen peroxide.
Protect container against physical damage. Store in a cool, dark room well-ventilated, and keep away from flammable and oxidizable substances. Drums may explode by heating or contact with water. Therefore, place drums on a palette to protect from washing water, drainage, etc. on the floor. Should not be kept long under insufficient ventilation in summer.
Sources of ignition, such as smoking and open flames, are prohibited where trichloroisocyanuric acid is used, handled, or stored in a manner that could create a potential fire or explosion hazard.
Safe Storage of Pesticides. Always store pesticides in their original containers, complete with labels that list ingredients, directions for use, and first aid steps in case of accidental poisoning. Never store pesticides in cabinets with or near food, animal feed, or medical supplies. Do not store pesticides in places where flooding is possible or in places where they might spill or leak into wells, drains, ground water, or surface water.
Cleanup Methods
SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.
Keep water away from release. Approach release from upwind. Isolate leaking containers, if this can be done without undue risk. Prompt cleanup and removal is necessary. Shovel into suitable dry container. control runoff and isolate discharged material for proper disposal.
Cover with weak reducing agent such as hypo, bisulfites or ferrous salts. Bisulfites or ferrous salts need additional promoter of some 3M-H2SO4 for rapid reaction. Transfer the slurry (or sludge) into a large container of water and neutralize with soda ash. Drain into the sewer with abundant water.
If a spill occurs, clean it up promptly. Don't wash it away. Instead, sprinkle the spill with sawdust, vermiculite, or kitty litter. Sweep it into a plastic garbage bag, and dispose of it as directed on the pesticide product label.
After Applying a Pesticide, Indoors or Outdoors. To remove pesticide residues, use a bucket to rinse tools or equipment three times, including any containers or utensils that you used when mixing the pesticide. Then pour the rinsewater into the pesticide sprayer and reuse the solution by applying it according to the pesticide product label directions. After applying any pesticide wash your hands and any other parts of your body that may have come in contact with the pesticide..To prevent tracking pesticides inside, remove or rinse your boots or shoes before entering your home. Wash any clothes that have been exposed to a lot of pesticide separately from your regular wash.
Disposal Methods
SRP: Criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
Add substance into dilute solution of sodium hydroxide or soda ash with stirring gradualy and neutralize that solution with reducing agents such as sodium sulfite and sodium thiosulfate. Adjust pH with sulfuric acid or hydrogen chloride to make neutral solution and dispose.
Evacuate persons not wearing protective equipment from area of spill or leak until clean-up is complete. Remove all ignition sources. Collect powdered material in the most convenient and safe manner and deposit in sealed containers. Ventilate area after clean-up is complete. It may be necessary to contain and dispose of this chemical as a hazardous waste. If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters.
Use vast volume of concentrated solution of reducing agent (bisulfites or ferrous salts with 3M-H2SO4 or hypo). Neutralize with soda ash or dilute hydrochloric acid. Drain into the sewer with abundant water.
For more Disposal Methods (Complete) data for Trichloroisocyanuric acid (6 total), please visit the HSDB record page.
毒性情報
Ecotoxicity Values
LC50; Species: Anas platyrhynchos (Mallard duck, age 14 days) diet >10000 ppm for 8 days
LC50; Species: Anas platyrhynchos (Mallard duck) diet >5000 ppm for 8 days
LC50; Species: Anas platyrhynchos (Mallard duck, age 9 days) diet >5620 ppm for 8 days
LD50; Species: Anas platyrhynchos (Mallard duck, age 14 days) oral via capsule 1890 mg/kg
For more Ecotoxicity Values (Complete) data for Trichloroisocyanuric acid (21 total), please visit the HSDB record page.
Environmental Fate
TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 25(SRC), determined from a water solubility of 1.2X10+4 mg/L(2) and a regression-derived equation(3), indicates that trichloroisocyanuric acid is expected to have very high mobility in soil(SRC). Volatilization of trichloroisocyanuric acid from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 6.2X10-11 atm-cu m/mole(SRC), using a fragment constant estimation method(4). Trichloroisocyanuric acid is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 1.6X10-8 mm Hg at 25 °C(SRC), determined from a fragment constant method(5). Biodegradation data for trichloroisocyanuric acid in the terrestrial environment were not available(SRC,2009). However, in the Japanese MITI test, trichloroisocyanuric acid reacted with water to form isocyanuric acid, which is confirmed to be biodegradable(6).
AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 25(SRC), determined from a water solubility of 1.2X10+4 mg/L(2) and a regression-derived equation(3), indicates that trichloroisocyanuric acid is not expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(4) based upon an estimated Henry's Law constant of 6.2X10-11 atm-cu m/mole(SRC), developed using a fragment constant estimation method(5). According to a classification scheme(6), an estimated BCF of 3.1(SRC), from its water solublity(2) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Trichloroisocyanuric acid is expected to undergo hydrolysis in the environment since this compound contains functional groups that hydrolyze under environmental conditions(4). Biodegradation data for trichloroisocyanuric acid in the aquatic environment were not available(SRC,2009). However, in the Japanese MITI test, trichloroisocyanuric acid reacted with water to form isocyanuric acid, which is confirmed to be biodegradable(8).
ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), trichloroisocyanuric acid, which has an estimated vapor pressure of 1.6X10-8 mm Hg at 25 °C(SRC), determined from a fragment constant method(2), is expected to exist solely in the particulate phase in the ambient atmosphere. Particulate-phase trichloroisocyanuric acid may be removed from the air by wet or dry deposition(SRC). Trichloroisocyanuric acid does not contain chromophores that absorb at wavelengths >290 nm(3) and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC).
Ecotoxicity Excerpts
/AQUATIC SPECIES/ The effects of trichloroisocyanuric acid (TCCA) ... on the freshwater alga Chlorella vulgaris were assessed by toxicity bioassays and by the values of biomarkers in phase I and phase II. The biomarkers included growth rate, concentration of chlorophyll a, activities of 7-ethoxyresorufin-O-dealkylases (EROD), glutathione S-transferase (GST), catalase (CAT), and total glutathione (GSH) ... Trichloroisocyanuric acid was a strong growth inhibitor and, at concentrations of greater than 0.80 mg/L, caused 100% inhibition on 24-hr exposure. The 96-hr EC50 of TCCA was 0.313 mg/L ... In TCCA exposure, GST activity was significantly stimulated, and GSH concentration was increased. Catalase activity increased only at TCCA concentrations of greater than 0.12 mg/L, and no change in EROD activity was observed.
/AQUATIC SPECIES/ This paper reports the acute toxicity of three biocides used in the disinfection of cooling towers, tetrakis(hydroxymethyl) phosphonium chloride (THPC), trichloroisocyanuric acid (TCIC), and sodium bromide (NaBr), on Artemia larvae, their effect on the phototactic response of this organism, and the potential of bioaccumulation in this species. The 24-hr median lethal concentration (LC50) values for these biocides with respect to 24-, 48-, and 72-hr-old Artemia, determined by static bioassays, showed the following rank order of toxicity: THPC < TCIC < NaBr. An age-dependent increase in sensitivity was seen for each compound. All three biocides reduced the phototactic response of 24-hr-old Artemia larvae in 24-hr static bioassays; the median inhibitory concentration ratios obtained were 30 to 40 times lower than their respective 24-hr LC50 values. The results suggest that phototaxis bioassays could provide the speed and simplicity required for screening many potential pollutants for harmful effects. The bioconcentration factors obtained for Artemia larvae exposed to 10% LC50 for 168 hr in renewal assays were 93.75, 1.67, and 0.23 for THPC, TCIC, and NaBr, respectively. This shows these biocides pose no bioaccumulation risk in this organism, although the value of 93.75 obtained for THPC is close to the threshold above which such a risk is considered to exist.
Signs and Symptoms
Cough. Sore throat. Laboured breathing.
Redness.
Redness. Pain. Burns.
Abdominal pain. Burning sensation. Shock or collapse.
Soil Adsorption/Mobility
The Koc of trichloroisocyanuric acid is estimated as 25(SRC), using a water solubility of 1.20X10+4 mg/L(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that trichloroisocyanuric acid is expected to have very high mobility in soil.
Human Toxicity Excerpts
/HUMAN EXPOSURE STUDIES/ Trichloroisocyanuric acid solution (neutralized, 100 mg/L as available chlorine) was tested on 10 individuals by immersion of the entire forearms eight times a day for 7 days and after a 2 wk rest repeated for 7 days. No skin irritation or sensitization was observed.
/SIGNS AND SYMPTOMS/ Human systemic effects by ingestion: ulceration or bleeding from stomach. Toxicity symptoms include emaciation, lethargy, weakness, and delayed death.
/CASE REPORTS/ Two patients were admitted to the hospital emergency room in respiratory distress after an accidental explosion involving chlorinating agents for the swimming pool. The two primary agents involved were calcium hypochlorite and trichloro-s-triazinetrione; both are commonly used chlorinating agents ...The amount of calcium hypochlorite primarily determines the rate of reaction and heat generation. Appropriate emergency action and treatment for chlorine gas is discussed.
/SURVEILLANCE/ Possible health hazards due to worker exposure to chlorinated isocyanurates at Olin Chemical, Lake Charles, Louisiana, were investigated. At the time of the survey about 90 workers were employed in production activities associated with packaging trichloroisocyanuric acid and sodium dichloroisocyanurate. Personal breathing zone sampling and medical interviews were performed. Particulate concentrations ranged from 0.11 to 38 mg/cu m. About 60% of the dust near the packaging areas was within the respirable size range. No OSHA standards for exposure to any chlorinated isocyanurates have been developed. Workers used respirator facepieces with high efficiency particulate filters. All production workers reported one or more work related symptoms. The most common symptoms were eye irritation and cough. 78% of the women interviewed reported problems or changes in their menstrual cycle since beginning work in the packaging area.
Artificial Pollution Sources
Trichloroisocyanuric acid's production and use as an active ingredient in household dry bleaches, dishwashing compounds, scouring powders, detergent sanitizers, commercial laundry bleaches, swimming-pool disinfectant, bactericide, algicide, bleach, and deodorant(1) may result in its release to the environment through various waste streams(SRC).
Environmental Biodegradation
AEROBIC: Cyanuric acid is ultimately the end product of use of chloroisocyanurates in bleaching, sanitizing, and disinfection applications. Since the N-chloro derivatives are biocidal, biodegradation studies have centered on the residual cyanuric acid, which has been shown to undergo biodegradation under environmental conditions(1). In the Japanese MITI test, trichloroisocyanuric acid reacted with water to form isocyanuric acid, which is confirmed to be biodegradable(2).
法規制情報
FIFRA Requirements
Residues of the following chemical substances are exempted from the requirement of a tolerance when used in accordance with good manufacturing practice as ingredients in an antimicrobial pesticide formulation, provided that the substance is applied on a semi-permanent or permanent food-contact surface (other than being applied on food packaging) with adequate draining before contact with food. ... (c) The following chemical substances when used as ingredients in an antimicrobial pesticide formulation may be applied to: Food-processing equipment and utensils. 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-trichloro- is included on this list. Limit: When ready for use, the end-use concentration of all di- or trichloroisocyanuric acid chemicals in the solution is not to exceed 100 ppm determined as total available chlorine.
The Agency has sufficient information on the health effects of the chlorinated isocyanurates and on their potential for causing adverse effects in fish and wildlife and the environment for all uses registered for these chemicals. The Agency therefore concludes that products containing the chlorinated isocyanurates for these uses are eligible for reregistration. Only product chemistry data on certain manufacturing use products are still needed. The Agency has determined that the chlorinated isocyanurate products, labeled and used as specified in this Reregistration Eligibility Document, will not pose unreasonable risks or adverse effects to humans or the environment.
As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their continued use. Under this pesticide reregistration program, EPA examines newer health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether the use of the pesticide does not pose unreasonable risk in accordance to newer saftey standards, such as those described in the Food Quality Protection Act of 1996. Sodium dichloroisocyanurate is found on List A, which contains most pesticides that are used on foods and, hence, have a high potential for human exposure. List A consists of the 194 chemical cases (or 350 individual active ingredients) for which EPA issued registration standards prior to FIFRA '88. Case No: 0569; Pesticide type: antimicrobial; Registration Standard Date: 5/20/88 PB88-220660; Case Status: RED Approved 09/02; OPP has made a decision that some/all uses of the pesticide are eligible for reregistration, as reflected in a Reregistration Eligibility Decision (RED) document .; Active ingredient (AI): trichloroisocyanuric acid; AI Status: OPP has completed a Reregistration Eligibility Decision (RED) for the case/AI.
安全データ
- wgk
- 2
- tsca
- TSCA listed
- rtecs
- XZ1925000
- ridadr
- UN 2468 (TRICHLOROISOCYANURIC ACID, DRY)
- 毒性
- LD50 orally in Rabbit: 406 mg/kg LD50 dermal Rabbit > 2000 mg/kg
- hs_code
- 29336980
- risk_code
- 8-22-31-36/37-50/53-36/37/38
- 化審法
- (5)-1044 優先評価化学物質
- hazard_code
- O,Xn,N
- safety_code
- 8-26-41-60-61
- hazard_class
- 5.1
- packing_group
- II
- Hazard Classifications
- Acute Tox. 4 OralAquatic Acute 1Aquatic Chronic 1Eye Irrit. 2Ox. Sol. 2STOT SE 3
- ストレージクラス
- 5.1B - Oxidizing hazardous materials
- 有毒物質データの
- 87-90-1(Hazardous Substances Data)
化学と産業
薬理情報
Metabolism/Metabolites
Both s-triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-trichloro- and s-triazine-2,4,6(1H,3H,5H)-trione, 1,3-dichloro-, sodium salt are unstable in the body (particularly the stomach) because the available chlorine is rapidly reduced. Cyanuric acid (or its monosodium salt) is the degradation product from both products.
用途と製造
Uses
Used in swimming pool sanitizers, industrial deodorants, bleaches, scouring powders, and dishwashing compounds; [HSDB] Used as a disinfectant, chlorinating agent, stainless steel cleaner, and non-shrink agent for wool; [Merck Index]
Metal Degreasing [Category: Clean]
For trichloroisocyanuric acid (USEPA/OPP Pesticide Code: 081405) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./
Fumigant
Microbicide/microbistat (slime forming bacteria, fungi, algae), disinfectant, sanitizer, fungicide, algicide, bacteriostat.
Chlorinating agent, disinfectant, industrial deodorant. In household cleansers. In removing oil and protein in stainless steel. In non-shrink treatment for wool. Oxidant and chlorinating reagent in organic synthesis.
U.S. Production
2023: 2,500,000 - <4,000,000 lb
(1972) 2.87X10+10 grams (di & tri & salts)
(1974) 3.63X10+10 g /Chlorinated isocyanurates/
1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-trichloro- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and/or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B; 51FR21438).
Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#2340]
Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-trichloro-. Aggreated National Production Volume: 500,000 to < 1 million lbs.
Consumption Patterns
(For all chlorinated isocyanurates-trichloroisocyanuric acid, sodium dichloroisocyanurate, and potassium dichloroisocyanurate) 53% as swimming pool sanitizer; 19.6% in commercial bleach; 7.6% in household bleach; 7.6% in dishwasher compounds; 6.1% in scouring powders; 6.1% in chlorinated cleaners and sanitizers (1974)
Methods of Manufacturing
Chlorination of trisodium cyanurate
Produced commercially in >90% yield by chlorination of aqueous trisodium cyanurate, prepared from cyanuric acid and sodium hydroxide in a 1:3 molar ratio. Another commercial process is based on the reaction of hypochlorous acid and chlorine with monosodium cyanurate. Can also be formed by reaction of preformed or in situ generated hypochlorous acid with cyanuric acid slurry or by reaction of dichlorine monoxide with finely powdered cyanuric acid.
N-Chloroisocyanuric acids are prepared by continuous reaction of chlorine with isocyanuric acid in aqueous sodium hydroxide at 0 - 15 °C. Careful control of pH and reaction temperature are essential to prevent the formation of explosive NCl3. /N-Chloroisocyanuric acids/
Formulations/Preparations
A complete list of currently registered active pesticide products can be found in the National Pesticide Information Retrieval System's USEPA/OPP Registered and Cancelled Pesticide Product Database. These pesticide products are registered for use in the U.S. but approved products may change periodically and so federal, state and local authorities must be consulted for currently approved products.
Bromoblend 99: Active Ingredients 68.6% 1-Bromo-3-chloro-5,5-dimethylhydantoin, 29.7% Trichloro-s-triazinetrione
Wonder Tab: Active Ingredients 18.19% Dichloro-s-triazinetrione, 66.96% Trichloro-s-triazinetrione
Super Puck: Active Ingredients 6.8% Boron sodium oxide (B4Na2O7), pentahydrate, 72.3% Trichloro-s-triazinetrione
For more Formulations/Preparations (Complete) data for Trichloroisocyanuric acid (46 total), please visit the HSDB record page.
General Manufacturing Information
Not Known or Reasonably Ascertainable
1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-trichloro-: ACTIVE
Powd mixt containing cyanuric acid, trichloroisocyanuric acid, and X2CO3 (X = Na,K) in defined molar ratios have optimum stability and solubility in water.
Trichloroisocyanuric acid was more effective in vitro against Pseudomonas aeruginosa, Staphylococcus aureus, and sporulating Bacillus subtilis and Candida albicans than against Shigella flexneri or Escherichia coli.
Used as source of available chlorine in "dry type" bleaches, scouring powders, dishwashing cmpd, and sanitizing cmpd. Org oxidant which can slowly oxidize almost its own wt of chloride ions to chlorine gas (about 90% available chlorine).
Theoretical available chlorine = 91.5%; Typical available chlorine = 90.0%
応用分野
用途有機物合成の際の塩素化剤、プールの殺菌剤、脱臭剤、家庭用クリーナー(殺菌剤)、ウールの縮毛防止剤
用途工業用として、下廃水、プール水、貯留水、用水の殺菌に使用される。試薬としては、抗菌、抗かび研究用として抗菌のメカニズムの研究や新規抗菌剤との比較、工業用としての検討などに使用される。
使用Trichloroisocyanuric Acid is a disinfectant and anti-bacterial. It can also be used in the synthesis of napthols.
一般的な説明A white slightly hygroscopic crystalline powder or lump solid with a mild chlorine-like odor. Said to have 85 percent available chlorine. Decomposes at 225°C. Moderately toxic by ingestion. May irritate skin and eyes. Active ingredient in household dry bleaches. Used in swimming pools as a disinfectant .
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