4-キノリノール

4-Hydroxyquinoline

HCID 69141CAS 529-37-3

基本情報

標準SMILES
O=c1cc[nH]c2ccccc12
InChIKey
PMZDQRJGMBOQBF-UHFFFAOYSA-N
分子式
C9H7NO
平均分子量
145.16 g/mol
単同位体質量
145.05276384

概要

4-quinolone is a quinolone that is 1,4-dihydroquinoline substituted by an oxo group at position 4. It is a tautomer of a quinolin-4-ol.

名称と識別子

優先名称
4-Hydroxyquinoline
IUPAC
1H-quinolin-4-one
現地名
4-キノリノール
英語名
4-Quinolinol
分子式
C9H7NO
分子量
145.16

名称と別名

4-HydroxyquinolineQuinolin-4-ol611-36-91H-quinolin-4-oneKynurineM1O131WXFODTXSID50209980CHEBI:15815RefChem:524086DTXCID00132471210-268-24-Quinolinol
名称をさらに表示
4-キノリノールキヌリンキノリン-4-オール4-ヒドロキシキノリン4-キノリンオール4ヒドロキシキノリン4-ヒドロキシキノロン4‐ヒドロキシキノリンAKOS 222-324-HydroxyquinoL4-Quinolinol 98%4-Quinolinol >
quinolin-4(1H)-one4(1H)-Quinolinone529-37-34-QuinoloneQuinoline, 4-hydroxy-MFCD000067774-hydroxy quinoline4-Chinolinol

データベース識別子

CAS
529-37-3、611-36-9
PubChem CID
69141
DTXSID
DTXSID50209980
ChEMBL
CHEMBL1232567
ChEBI
CHEBI:155900
UNII
M1O131WXFO
EC Number
210-268-2
Nikkaji
J387.250E、J7.017C

物性

構造計算による物性

XLogP
0.6
極性表面積
29.1 Ų
水素結合供与体数
1
水素結合受容体数
2
回転可能結合数
0
重原子数
11

実験および物理化学的性質

LogP0.58

物理化学的性質

融点
200 · 200-202 °C(lit.)
沸点
264.27 °C · 264.27°C (rough estimate)
比重(密度)
1.1555 · 1.1555 (rough estimate)
屈折率
1.45 · 1.4500 (estimate)
貯蔵温度
Sealed in dry,Room Temperature
溶解性
メタノールに可溶。

化学的性質

化学的特性LIGHT BEIGE TO YELLOWISH CRYST. POWDER OR NEEDLES

安全と法規制

GHS分類

GHS Classification · 4 件

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 49 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Hazard Classes and CategoriesSkin Irrit. 2 (100%)

安全データ

wgk
3
rtecs
VC4070000
hs_code
29334900
risk_code
36/37/38
hazard_code
Xi
safety_code
26-36-37/39

化学と産業

応用分野 · 4 件

用途有機合成原料。

説明4-Hydroxyquinoline is a quinoline alkaloid that has been found in Z. lotus honeys. It is a core component of alkyl-4-hydroxyquinoline quorum sensing molecules such as 2-heptyl-3-hydroxy-4(1H)-quinolone and 2-nonyl-3-hydroxy-4-quinolone. 4-Hydroxyquinoline has been used as a precursor in the synthesis of compounds with antibacterial activity. It has also been used as a fluorescent detection reagent for iron(III) in bovine liver samples.

使用4-Hydroxyquinolineis is a raw material in medical research, a hydroxylated quinoline derivative with antimicrobial activity. 4-Hydroxyquinoline showed growth-inhibitory effects against intestinal bacteria. 4-Hydroxyquinoline act as sacrifi cial scavengers of the photogenerated oxygen species and has been shown to prevent the photodegradation of riboflavin.

一般的な説明4-Quinolinol (4-quinolone) is a quinolone compound which forms the core moiety of antibacterials such as norfloxacin, nalidixic acid, ciprofloxacin and cinoxacin.

サプライヤー38 社

苏州道澜生物医药科技有限公司15952404857 · [email protected]
合肥曼奇诺生物医药技术有限公司19719236623 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
杭州品高化工有限公司0571-87658025 · [email protected]
宁波季诺化学品有限公司0574-87314919 057487319282 · [email protected]

補足説明

定義ChEBI: A monohydroxyquinoline carrying a hydroxy group at position 4.

関連反応

9 件

関連ノート

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