N-Methylmaleimide (HCID 70261)

名称と識別子

優先名称: N-Methylmaleimide
IUPAC: 1-methylpyrrole-2,5-dione
現地名: N-メチルマレイミド
英語名: N-Methylmaleimide
分子式: C5H5NO2
分子量: 111.1

名称と別名

N-Methylmaleimide930-88-1Maleimide, N-methyl-N-Methylmaleinimide1H-Pyrrole-2,5-dione, 1-methyl-P0TFZ8R21YNSC-57594DTXSID30239240RefChem:830735DTXCID50161731213-226-11-Methyl-1H-pyrrole-2,5-dione

名称をさらに表示

N-メチルマレイミドN-メチルマレインイミド1-メチル-2,5-ジヒドロ-1H-ピロール-2,5-ジオン1-メチル-1H-ピロール-2,5-ジオン1-メチル-3-ピロリン-2,5-ジオンN‐メチルマレイミドN-メチルマレイミド, 98+%N-Methyl-MalemideN-Methylmaleimide>N-Methylmaleimide,97%N-Methylmaleimide,98+%

1-methylpyrrole-2,5-dioneN-methyl maleimide1-methyl-pyrrole-2,5-dioneMFCD00005508n-methylmaleimidmaleimide,n-methyl-1-methyl-2,5-dihydro-1H-pyrrole-2,5-dionemaleins|Aure-n-methylimid

データベース識別子

CAS: 930-88-1
PubChem CID: 70261
DTXSID: DTXSID30239240
ChEMBL: CHEMBL225037
ChEBI: CHEBI:232160
UNII: P0TFZ8R21Y
EC Number: 213-226-1
Nikkaji: J41.604E

物性

構造計算による物性

XLogP: -0.5
極性表面積: 37.4 Å²
水素結合供与体数: 0
水素結合受容体数: 2
回転可能結合数: 0
重原子数: 8
形式電荷: 0
複雑度: 153

実験および物理化学的性質

Kovats Retention Index925.1

物理化学的性質

融点: 94 · 94-96 °C (lit.)
沸点: 208.19 °C · 208.19°C (rough estimate)
比重(密度): 1.3113 · 1.3113 (rough estimate)
屈折率: 1.426 · 1.4260 (estimate)
貯蔵温度: Keep in dark place,Sealed in dry,Room Temperature
溶解性: Chloroform (Sparingly), Methanol (Slightly)
酸解離定数(Pka): -2.18 · -2.18±0.20(Predicted)
外見: クリスタル
色: ライトイエロー
水溶解度: 水にわずかに溶ける。
BRN: 108550 · 108550
InChI: InChI=1S/C5H5NO2/c1-6-4(7)2-3-5(6)8/h2-3H,1H3
InChIKey: SEEYREPSKCQBBF-UHFFFAOYSA-N
SMILES: N1(C)C(=O)C=CC1=O
CAS データベース: 930 · 930-88-1(CAS DataBase Reference)
NISTの化学物質情報: N-Methylmaleimide(930-88-1)

化学的性質

化学的特性light yellow crystals

安全と法規制

GHS分類

GHS Classification · 5 件

Danger

H302 (92.5%): Harmful if swallowed [Warning Acute toxicity, oral]；H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]；H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]

P260, P261, P264, P270, P272, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P330, P333+P317, P362+P364, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 53 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Hazard Classes and CategoriesAcute Tox. 4 (92.5%)；Skin Corr. 1C (100%)；Skin Sens. 1 (100%)

安全データ

F: 10-21
wgk: 3
rtecs: ON5600000
ridadr: UN 1759 8/PG 2
hs_code: 29241990
risk_code: 22-34-43-25-20/21
hazard_code: C
safety_code: 26-36/37/39-45
hazard_class: 6.1
packing_group: II
Hazard Classifications: Acute Tox. 4 OralSkin Corr. 1BSkin Sens. 1
ストレージクラス: 8A - Combustible corrosive hazardous materials

化学と産業

応用分野

使用N-Methylmaleimide is an electron deficient olefin that acts as a thiol-blocking reagent.

調製方法

純化方法Crystallise the imide three times from diethyl ether. Dry it in vacuo.[Beilstein 21/10 V 5.]

上流・下流製品情報

上流原料

N,N-ジエチルアニリンローダミンB溶液無水マレイン酸メチルアミン塩酸塩

下流製品

フェンスクシミド 1-メチル-2,5-ピロリジンジオン 1-Methyl-3-phenyl-1H-pyrrole-2,5-dione Pyrrolo[3,4-c]pyrrole-1,3(2H,3aH)-dione, tetrahydro-2-methyl-

サプライヤー50 社

国药集团化学试剂有限公司86-21-63210123 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

阿诺西（上海）生物技术有限公司400-1107768 15058188853 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

湖南韵邦生物科技股份有限公司85561037 15386497078 · [email protected]

N-メチルマレイミド

基本情報