1-フェニルピペラジン・2塩酸塩
1-Phenylpiperazine
データを補完しています。しばらくしてからページを更新すると最新の内容を表示できます
基本情報
- CAS
4004-95-9- 標準SMILES
c1ccc(N2CCNCC2)cc1- InChIKey
YZTJYBJCZXZGCT-UHFFFAOYSA-N- 分子式
- C10H14N2
- 平均分子量
- 162.23 g/mol
- 単同位体質量
- 162.11569846
名称と識別子
- 優先名称
- 1-Phenylpiperazine
- IUPAC
- 1-phenylpiperazine
- 現地名
- 1-フェニルピペラジン・2塩酸塩
- 英語名
- 1-Phenylpiperazine dihydrochloride
- 分子式
- C10H16Cl2N2
- 分子量
- 235.15
名称と別名
1-PHENYLPIPERAZINE92-54-6PhenylpiperazineDTXSID8057855J9225CBI7DDTXCID9031644RefChem:173105202-165-6N-PhenylpiperazinePiperazine, 1-phenyl-1-Phenyl-piperazineN-Phenyldiethylenediamine
名称をさらに表示
1-フェニルピペラジン・2塩酸塩Nsc1508471-Phenylpiperazine2HCl1-Phenylpiperazine hHdrochloridePhenylpiperazine (hydrochloride)1-Phenylpiperazine dihydrochlorideN-Phenylpiperazine Dihydrochloride4-Phenylpiperazine Dihydrochloride1-PHENYLPIPERAZINE DIHYDROCHLORIDE 98%Piperazine, 1-phenyl-, dihydrochloride
4-phenylpiperazinen-phenyl piperazineMFCD00005957CHEMBL94341-Fenylpiperazin1-Fenylpiperazin [Czech]N-phenylpiperazinCCRIS 4334
データベース識別子
- CAS
4004-95-9、92-54-6- PubChem CID
- 7096
- DTXSID
DTXSID8057855- ChEMBL
CHEMBL9434- UNII
- J9225CBI7D
- EC Number
- 202-165-6
- Nikkaji
- J35.451A
物性
構造計算による物性補完中
- XLogP
- 1.1
- 極性表面積
- 15.3 Ų
- 水素結合供与体数
- 1
- 水素結合受容体数
- 2
- 回転可能結合数
- 1
- 重原子数
- 12
- 形式電荷
- 0
- 複雑度
- 124
実験および物理化学的性質
Dissociation Constants9
物理化学的性質
- 融点
- 221 · 221-223°C
- 貯蔵温度
- Hygroscopic, Refrigerator, Under Inert Atmosphere
- 溶解性
- DMSO（微量）、メタノール（微量）、水（微量）
- 外見
- 個体
- 色
- ホワイトからオフホワイト
- 安定性
- 吸湿性
化学的性質
化学的特性White Solid
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
Danger
H301 (96.9%): Toxic if swallowed [Danger Acute toxicity, oral]；H310 (36.9%): Fatal in contact with skin [Danger Acute toxicity, dermal]；H311 (61.5%): Toxic in contact with skin [Danger Acute toxicity, dermal]；H314 (98.5%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
P260, P262, P264, P270, P280, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P330, P361+P364, P363, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 65 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
危険有害性情報
Regulatory Information
Status: Active Update: 09-04-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/21606
Piperazine, 1-phenyl-, dihydrochloride: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Phenylpiperazine: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesAcute Tox. 3 (96.9%)；Acute Tox. 2 (36.9%)；Acute Tox. 3 (61.5%)；Skin Corr. 1B (98.5%)
法規制情報
Regulatory Information
Status: Active Update: 09-04-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/21606
化学と産業
薬理情報
MeSH Pharmacological Classification
Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
A loosely defined grouping of drugs that have effects on psychological function. Here the psychotropic agents include the antidepressive agents, hallucinogens, and tranquilizing agents (including the antipsychotics and anti-anxiety agents).
用途と製造
General Manufacturing InformationPiperazine, 1-phenyl-: INACTIVE
応用分野
使用1-Phenylpiperazine was tested for its activity as a topical glaucoma agent.
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