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13280-60-9Nc1ccc([N+](=O)[O-])c(C(=O)[O-])c113280-60-9化学的特性5-Amino-2-nitrobenzoic acid appears as a yellow powder or crystal. Its crystal structure is: the 5-amino-2-nitrobenzoic acid crystallizes in the monoclinic P21/c space group with a = 3.898(2), b = 13.531(3), c = 14.301(3) , and β = 90.83(3). The adjacent molecules form a cyclic dimmer by intermolecular hydrogen bonds of type O H···O with their carboxyl groups. In the crystal structure NH2 group forms a threecenter hydrogen bond with oxygen atoms of NO2 group.
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用途有機合成原料。
説明5-Amino-2-nitrobenzoic acid is a reagent used in preparation of polymer-bound diazonium salts and insulin receptor tyrosine kinase activator. It is also used in 2-component dendritic chain reactions and activation of hydrophobic dendrimers.
使用Reactant for:Two-component dendritic chain reactionsEnzymic activation of hydrophobic self-immolative dendrimersPreparation of insulin receptor tyrosine kinase activatorPreparation of polymer-bound diazonium salts using Merrifield resin-bound piperazine
純化方法Crystallise the acid from water. [Beilstein 14 III 1021.]
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