DL-グリセルアルデヒド 3-リン酸 溶液
DL-グリセルアルデヒド 3-リン酸 溶液 · グリセルアルデヒド 3-リン酸 · rac-(R*)-2-ヒドロキシ-3-(ホスホノオキシ)プロパナール · DL-グリセルアルデヒド3-りん酸 · rac-(2R*)-2-ヒドロキシ-3-(ホスホノオキシ)プロパナール · rac-りん酸(2R*)-2-ヒドロキシ-3-オキソプロピル · rac-(R*)-2,3-ジヒドロキシプロパナール3-りん酸 · 5G
識別子と物理属性
| CAS No. | 591-59-3 |
|---|---|
| 分子式 | C3H7O6P |
| 平均分子量 | 170.06 g/mol |
| 単同位体質量 | 169.99802494 g/mol |
| SMILES | O=CC(O)COP(=O)(O)O |
| InChIKey | LXJXRIRHZLFYRP-UHFFFAOYSA-N |
| PubChem CID | 729 |
| ChEBI | CHEBI:17138 |
| EC No. | 209-721-7 |
| DTXSID | DTXSID40861814 |
| 現地名 | DL-グリセルアルデヒド 3-リン酸 溶液 |
化学・物理的性質
| XLogP | -2.7 |
|---|---|
| 極性表面積 | 104 |
| 水素結合供与体数 | 3 |
| 水素結合受容体数 | 6 |
| 回転可能結合数 | 4 |
| 重原子数 | 10 |
| 形式電荷 | 0 |
| 複雑度 | 149 |
| 沸点 | 399.2±52.0 °C(Predicted) |
| 密度 | 1.721±0.06 g/cm3(Predicted) |
| 貯蔵条件 | -20°C |
| 溶解度 | Water: 50 mg/ml |
| pKa（酸解離定数） | 1.80±0.10(Predicted) |
| 外観・状態 | Liquid |
| 色 | Colorless to light yellow |
| 由来生物 | synthetic (organic) |
| InChI | InChI=1S/C3H7O6P/c4-1-3(5)2-9-10(6,7)8/h1,3,5H,2H2,(H2,6,7,8) |
| InChIKey | LXJXRIRHZLFYRP-UHFFFAOYSA-N |
| SMILES | C(=O)C(O)COP(O)(O)=O |
安全性と法規制
| GHS 分類 | DangerH314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]H318 (97.4%): Causes serious eye damage [Danger Serious eye damage/eye irritation]P260, P264, P264+P265, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P363, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Hazard Classes and Categories | Skin Corr. 1B (100%)Eye Dam. 1 (97.4%) |
| 水環境危害等級（WGK） | 3 |
| 輸送番号（UN） | UN 1760 8/PG 2 |
| 危険文句（R） | 34 |
| 危険表示 | C |
| 安全措置（S） | 26-27-36/37/39-45 |
| 危険等級 | 8Eye Dam. 1Skin Corr. 1B |
| 包装等級 | II |
| 貯蔵分類 | 8A - Combustible corrosive hazardous materials |
用途
説明
DL-Glyceraldehyde-3-phosphate (GADP) is an intermediate in several metabolic pathways, including glycolysis and gluconeogenesis. In glycolysis, it can be derived from fructose 1,6-bisphosphate by fructose bisphosphate aldolase in a reaction that also produces dihydroxyacetone phosphate (DHAP). Triose phosphate isomerase reversibly converts DHAP to GADP. GADP is processed to 1,3-bisphosphoglycerate by glyceraldehyde phosphate dehydrogenase and NAD+.
使用
The level of Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) activity in HEK 293 cells was aβeβed by measuring the reduction of NAD+ by DL-Glyceraldehyde 3-phosphate.