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テトラヒドロメチルフラン
テトラヒドロメチルフラン · DIMETHYLTETRAHYDROFURAN · Tetrahydromethylfuran · 2-methyl-furamethyltetrahydrofuran
識別子と物理属性
| CAS No. | 25265-68-3 |
|---|---|
| 分子式 | C5H10O |
| 平均分子量 | 86.13 g/mol |
| 単同位体質量 | 86.07316494 g/mol |
| SMILES | CC1CCCO1 |
| InChIKey | JWUJQDFVADABEY-UHFFFAOYSA-N |
| PubChem CID | 7301 |
| ChEMBL | CHEMBL1580503 |
| EC No. | 202-507-4 |
| DTXSID | DTXSID9030258 |
| 現地名 | テトラヒドロメチルフラン |
化学・物理的性質
| XLogP | 1 |
|---|---|
| 極性表面積 | 9.2 |
| 水素結合供与体数 | 0 |
| 水素結合受容体数 | 1 |
| 回転可能結合数 | 0 |
| 重原子数 | 6 |
| 形式電荷 | 0 |
| 複雑度 | 43.2 |
| 物質分類 | Flammable agents - 3rd degree |
| Solvents | Solvents -> Ethers (<C12) |
| 密度 | 0.853 @ 20°C |
| 沸点 | 80 °C @760 [mm Hg]77-78 °C |
| 蒸気圧 | 97.3 [mmHg] |
| Physical Description | Methyltetrahydrofuran appears as a colorless liquid with an ether-like odor. Less dense than water. Vapors heavier than air. Used to make other chemicals and as a solvent.Clear, colorless to yellow liquid with a mildly irritating odor of ether[NTP: CSWG] |
| EPAの化学物質情報 | Furan, tetrahydromethyl- (25265-68-3) |
安全性と法規制
| GHS 分類 | DangerH225 (85.6%): Highly Flammable liquid and vapor [Danger Flammable liquids]P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 439 reports by companies from 22 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids] |
|---|---|
| 規制情報 | Chemical: Furan, tetrahydro-2-methyl-Furan, tetrahydro-2-methyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Furan, tetrahydro-2-methyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 28-02-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/13699Furan, tetrahydro-2-methyl-: HSNO Approval: HSR001202 Approved with controlsThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| 輸送ラベル（DOT） | Flammable Liquid |
| 火災危険 | Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:· HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. |
| 健康有害性 | Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:· Inhalation or contact with material may irritate or burn skin and eyes. |
| 有害性の概要 | Stabilized with 0.025% BHT (CAS# 128-37-0)An eye irritant[Sigma-Aldrich MSDS] See Tetrahydrofuran. |
| 輸送番号・ガイド（DOT） | 2536 127 |
| 反応性グループ | Ethers |
| Reactivity Alerts | Highly Flammable |
| Reactivity Profile | METHYLTETRAHYDROFURAN reacts violently with oxidants, causing fire and explosion hazards [Handling Chemicals Safely 1980. p. 891]. |
| DOT Hazard Classification | MethyltetrahydrofuranUN2536Class 3 Flammable and combustible liquid (49 eCFR § 173.120)PG II: the degree of danger presented by the material is medium |
| Air and Water Reactions | Highly flammable. Partially soluble in water. Oxidizes readily in air to form unstable peroxides that may explode spontaneously [Bretherick 1979. p.151-154, 164]. |
| Peroxide Forming Chemical | 2-MethyltetrahydrofuranB*: Compounds that form peroxides on concentration (distillation/evaporation)5 samples had 0-100 ppm peroxideage >1-10+ yrsKellyUnstabilized MeTHF may quickly form peroxides. See Millapore Sigma Sheet linked for more information.https://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma-Aldrich/General_Information/1/greener-solvents-br-ms.PDF |
| 消火 | Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]: |
| 漏出応急措置 | · CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. |
| 応急処置 | Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:General First Aid: |
| 暴露管理・個人防護 | · Wear positive pressure self-contained breathing apparatus (SCBA). |
| 非火災時の漏出対応 | Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]: |
| Isolation and Evacuation | Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]:Immediate precautionary measure |
| Protective Action Criteria (PAC) | 4.0 [ppm]44 [ppm]270 [ppm] |
| Personal Protective Equipment (PPE) | Excerpt from ERG Guide 127 [Flammable Liquids (Water-Miscible)]: |
| Emergency Response Planning Guidelines | CAUTION: The majority of these products have a very low flash point. Use of water spray when fighting fire may be inefficient. |
| 有害作用 | Neurotoxin - Acute solvent syndrome |
| Toxicity Data | LC50 (rat) = 6,000 ppm/4hr |
用途
一般的な説明
A colorless liquid with an ether-like odor. Less dense than water. Flash point 12°F. Vapors heavier than air. Used to make other chemicals and as a solvent.