2-エチルピリジン
2-エチルピリジン · 2‐エチルピリジン · Pyridine, 2-ethyl- · a-Ethylpyridine · 2-ethyl-pyridin · 2-ethvlpvridine · 2-ETHYLPYRIDINE · 2-Ethylpyridine>ALPHA-ETHYLPYRIDINE
識別子と物理属性
| CAS No. | 100-71-0 |
|---|---|
| 分子式 | C7H9N |
| 平均分子量 | 107.15 g/mol |
| 単同位体質量 | 107.07349929 g/mol |
| SMILES | CCc1ccccn1 |
| InChIKey | NRGGMCIBEHEAIL-UHFFFAOYSA-N |
| PubChem CID | 7523 |
| ChEMBL | CHEMBL279305 |
| EC No. | 202-881-9 |
| DTXSID | DTXSID4021844 |
| 現地名 | 2-エチルピリジン |
化学・物理的性質
| XLogP | 1.7 |
|---|---|
| 極性表面積 | 12.9 |
| 水素結合供与体数 | 0 |
| 水素結合受容体数 | 1 |
| 回転可能結合数 | 1 |
| 重原子数 | 8 |
| 形式電荷 | 0 |
| 複雑度 | 61.4 |
| 物質分類 | Nitrogen Compounds -> Pyridines |
| SpringerMaterials Properties | Boiling point |
| LogP（分配係数） | 1.6 |
| 香味料 | EU Flavoring substances |
| 蒸気圧 | 4.89 [mmHg] |
| Physical Description | Colorless liquid with an unpleasant odor[Alfa Aesar MSDS] |
| 融点 | -63°C |
| 沸点 | 149 °C (lit.) |
| 密度 | 0.937 g/mL at 25 °C (lit.) |
| 屈折率 | n20/D 1.496(lit.) |
| 引火点 | 85 °F |
| 貯蔵条件 | Flammables area |
| 溶解度 | 42g/リットル約 45 g/L (20 °C) |
| 外観・状態 | clear liquid |
| pKa（酸解離定数） | 5.89(at 25℃) |
| 色 | Colorless to Almost colorless |
| 臭い | プロピレングリコール中0.01%。草の匂い |
| においのタイプ | 緑 |
| BRN | 106480 |
| ヘンリー定数 | 6.0×10-1 mol/(m3Pa) at 25℃, Andon et al. (1954) |
| 誘電率 | 8.3300000000000001 |
| InChI | 1S/C7H9N/c1-2-7-5-3-4-6-8-7/h3-6H,2H2,1H3 |
| InChIKey | NRGGMCIBEHEAIL-UHFFFAOYSA-N |
| SMILES | CCc1ccccn1 |
| LogP（分配係数） | 1.690 |
| CAS データベース | 100-71-0(CAS DataBase Reference) |
| NISTの化学物質情報 | Pyridine, 2-ethyl-(100-71-0) |
| EPAの化学物質情報 | 2-Ethylpyridine (100-71-0) |
化学的特性
clear colorless to yellowish liquid
安全性と法規制
| GHS 分類 | WarningH226 (99.5%): Flammable liquid and vapor [Warning Flammable liquids]P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P317, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 204 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 規制情報 | Chemical: Pyridine, 2-ethyl-Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)Status: Cease Manufacture Update: 14-03-2017 https://echa.europa.eu/registration-dossier/-/registered-dossier/192212-Ethylpyridine: Does not have an individual approval but may be used under an appropriate group standard |
| 有害性の概要 | A skin and strong eye irritantHarmful by ingestion, inhalation, and skin absorption[Alfa Aesar MSDS] See Pyridine. |
| Hazard Classes and Categories | Flam. Liq. 3 (99.5%) |
| F | 8 |
| 水環境危害等級（WGK） | 3 |
| TSCA 収載状態 | TSCA listed |
| 輸送番号（UN） | UN 1993 3/PG 3 |
| 税関コード | 29333999 |
| 危険文句（R） | 10-36/37/38 |
| 化審法 | (9)-222 |
| 消防法 | 危-4-2-III |
| 危険表示 | Xi |
| 安全措置（S） | 26-36 |
| 危険等級 | 3Acute Tox. 4 DermalAcute Tox. 4 InhalationEye Irrit. 2Flam. Liq. 3Skin Irrit. 2STOT SE 3 |
| 包装等級 | III |
| 貯蔵分類 |
用途
使用
2-Ethylpyridine is used to study its effect on the proliferation and survival of human umbilical vein endothelial cells (HUVECs), HMVECs from lung, and NIH 3T3 cells. 2-Ethylpyridine linked with silica is a popular stationary phase for chiral and achiral separations in supercritical fluid chromatography.
一般的な説明
2-Ethylpyridine, a nitrogen aromatic compound, is grouped under the class of azaarenes. It is generally found as a component of fuels and combustion products.
製法・合成法
純化方法
Purify it further by conversion to the picrate, recrystallisation of the picrate and regeneration of the free base followed by distillation. [Beilstein 20/6 V 3.]