Lauryl Phosphate (HCID 75816)

概要

The CIR Expert Panel concluded the following 28 alkyl phosphates are safe in the present practices of use and concentration in cosmetics when formulated to be non-irritating...Lauryl Phosphate...

名称と識別子

優先名称: Lauryl Phosphate
IUPAC: dodecyl dihydrogen phosphate
現地名: りん酸ドデシル
英語名: Dodecyl dihydrogen phosphate
分子式: C12H27O4P
分子量: 266.31

名称と別名

Dodecyl dihydrogen phosphate2627-35-2Lauryl phosphateMonolauryl phosphateMonododecyl phosphateDihydrogen monolauryl phosphatePhosphoric acid, monododecyl esterLauryl dihydrogen phosphate0K08L8GE2HEINECS 220-095-4lauryl monophosphaten-dodecyl phosphate

名称をさらに表示

りん酸二水素ドデシルりん酸ドデシルりん酸ラウリルラウリルアシッドホスフェ-トドデカン-1-イル＝二水素＝ホスファートりん酸モノ-N-ドデシル, TECHりん酸モノ-n-ドデシル, tech. 90%mono-n-DodecyLDODECYL PHOSPHATELauryl acid phosphatemono-lauryl phosphateChrome mist inhibitorDODECYLPHOSPHORIC ACIDMONO-DODECYL PHOSPHATEMONO-N-DODECYL PHOSPHATEDodecyldihydrogenphosphat

NSC 41919DODECYL ACID PHOSPHATEROMOL MAP HDODECANYL PHOSPHATENIKKOL PHOSTEN HLPNSC-41919PHOSPHANOL ML-200ETHFAC 102

データベース識別子

CAS: 2627-35-2
PubChem CID: 75816
DTXSID: DTXSID70880492
ChEMBL: CHEMBL187711
UNII: 0K08L8GE2H
EC Number: 220-095-4
Nikkaji: J192.141J

物性

構造計算による物性

XLogP: 4
極性表面積: 66.8 Å²
水素結合供与体数: 2
水素結合受容体数: 4
回転可能結合数: 12
重原子数: 17
形式電荷: 0
複雑度: 203

実験および物理化学的性質

Chemical ClassesOther Classes -> Organophosphates, Other

Cosmetics · 2 件

Cosmetic ingredients (Lauryl Phosphate) -> CIR (Cosmetic Ingredient Review)

Emulsifying

Physical DescriptionWhite odorless crystals; [Alfa Aesar MSDS]

物理化学的性質

融点: 39 · 39-45°C
沸点: 385.5 · 385.5±25.0 °C(Predicted)
比重(密度): 1.056 · 1.056±0.06 g/cm3(Predicted)
酸解離定数(Pka): 1.95 · 1.95±0.10(Predicted)
外見: 白からオフホワイトの固体。
水溶解度: 水に不溶。
BRN: 1710518 · 1710518
InChI: 1S/C12H27O4P/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15/h2-12H2,1H3,(H2,13,14,15)
InChIKey: TVACALAUIQMRDF-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCOP(O)(O)=O
CAS データベース: 2627 · 2627-35-2(CAS DataBase Reference)
EPAの化学物質情報: Monolauryl phosphate (2627-35-2)

安全と法規制

GHS分類

GHS Classification · 4 件

Danger

H314 (14.3%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P261, P264, P264+P265, P271, P273, P280, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P319, P321, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 7 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Regulatory Information · 2 件

Chemical: Phosphoric acid, monododecyl ester

Phosphoric acid, monododecyl ester: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazards SummaryPowder causes eye irritation; [Alfa Aesar MSDS] See Monooctyl phosphate.

Hazard Classes and CategoriesSkin Corr. 1B (14.3%)

毒性情報

Toxicity Summary · 2 件

The CIR Expert Panel concluded the following 28 alkyl phosphates are safe in the present practices of use and concentration in cosmetics when formulated to be non-irritating...Lauryl Phosphate...

Safe for use in cosmetics, with qualifications

安全データ

wgk: WGK 2
tsca: TSCA listed
ridadr: 3261
risk_code: 36/37/38-43-41-37/38
hazard_code: Xi
safety_code: 26-36/37/39-45
Hazard Classifications: Eye Dam. 1Skin Irrit. 2Skin Sens. 1STOT SE 3
ストレージクラス: 10 - Combustible liquids

化学と産業

用途と製造

UsesCIR ingredient: Lauryl Phosphate

Use ClassificationCosmetics -> Emulsifying

General Manufacturing InformationPhosphoric acid, monododecyl ester: ACTIVE

応用分野

使用mono-n-Dodecyl phosphate is a lysophosphatidic acid (LPA) receptor ligand which serves as a specific agonist at EDG-4 (LPA2) (EC50=700 nM) and antagonist at EDG-7