酢酸4-ビニルフェニル
酢酸4-ビニルフェニル · 4-ビニルフェノールアセタート · 酢酸p-ビニルフェニル · 酢酸4-エテニルフェニル · 1-アセトキシ-4-ビニルベンゼン · スチレン-4-オールアセタート · 4-アセトキシスチレン · p-アセトキシスチレン
識別子と物理属性
| CAS No. | 2628-16-2 |
|---|---|
| 分子式 | C10H10O2 |
| 平均分子量 | 162.18 g/mol |
| 単同位体質量 | 162.06807956 g/mol |
| SMILES | C=Cc1ccc(OC(C)=O)cc1 |
| InChIKey | JAMNSIXSLVPNLC-UHFFFAOYSA-N |
| PubChem CID | 75821 |
| ChEMBL | CHEMBL3186305 |
| EC No. | 434-600-2 |
| DTXSID | DTXSID2044898 |
| 現地名 | 酢酸4-ビニルフェニル |
化学・物理的性質
| XLogP | 2.5 |
|---|---|
| 極性表面積 | 26.3 |
| 水素結合供与体数 | 0 |
| 水素結合受容体数 | 2 |
| 回転可能結合数 | 3 |
| 重原子数 | 12 |
| 形式電荷 | 0 |
| 複雑度 | 167 |
| Physical Description | Liquid |
| 融点 | 7-8 °C (lit.) |
| 沸点 | 260 °C (lit.) |
| 密度 | 1.06 g/mL at 25 °C (lit.) |
| 屈折率 | n20/D 1.538(lit.) |
| 引火点 | 190 °F |
| 貯蔵条件 | 2-8°C |
| 外観・状態 | 液体 |
| 色 | 無色透明 |
| BRN | 1862793 |
| InChI | InChI=1S/C10H10O2/c1-3-9-4-6-10(7-5-9)12-8(2)11/h3-7H,1H2,2H3 |
| InChIKey | JAMNSIXSLVPNLC-UHFFFAOYSA-N |
| SMILES | C1(OC(=O)C)=CC=C(C=C)C=C1 |
| CAS データベース | 2628-16-2(CAS DataBase Reference) |
| NISTの化学物質情報 | Phenol, 4-ethenyl-, acetate(2628-16-2) |
| EPAの化学物質情報 | Phenol, 4-ethenyl-, acetate (2628-16-2) |
化学的特性
4-Acetoxystyrene is a clear and colorless liquid that is essentially the acetic acid ester of p-vinylphenol. It will homopolymerize readily in the same manner that styrene homopolymerizes and can also be copolymerized with styrene and with monomers which are copolymerizable with styrene. 4-Acetoxystyrene is homopolymerized and copolymerized in aqueous emulsion and, without isolation, the polymer is hydrolyzed to homopolymers and copolymers of p-vinylphenol with a base. Homopolymers and copolymers of p-vinylphenol are used as epoxy resin curing agents and in the preparation of epoxy resins by reaction with epichlorohydrin.
安全性と法規制
| GHS 分類 | DangerH302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]P260, P261, P262, P264, P264+P265, P270, P271, P272, P273, P280, P284, P301+P317, P302+P352, P304+P340, P305+P351+P338, P316, P319, P320, P321, P330, P332+P317, P333+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 171 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 規制情報 | Phenol, 4-ethenyl-, 1-acetate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phenol, 4-ethenyl-, 1-acetate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.Status: Active Update: 16-02-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/24914Phenol, 4-ethenyl-, acetate: Does not have an individual approval but may be used under an appropriate group standard |
| Hazard Classes and Categories | Acute Tox. 4 (100%) |
| 水環境危害等級（WGK） | 3 |
| TSCA 収載状態 | TSCA listed |
| RTECS 番号 | SL3784000 |
| 輸送番号（UN） | 2810 |
| 毒性 | LD50 orl-rat: 1503 mg/kg EPASR* 8EHQ-1190-1082 |
| 税関コード | 29153900 |
| 危険文句（R） | 22-38-43-36/38 |
| 化審法 | (3)-2784 |
| 消防法 | 危-4-3-III |
| 危険表示 | Xn |
| 安全措置（S） | 36/37-26 |
| 危険等級 | 6.1Acute Tox. 4 OralEye Irrit. 2Skin Irrit. 2Skin Sens. 1 |
| 包装等級 | III |
| 貯蔵分類 | 10 - Combustible liquids |
用途
説明
4-Acetoxystyrene can be used to synthesize Poly(p-hydroxystyrene) as the main component of photoresist. The chemically amplified photoresist of the poly(p-hydroxystyrene) series is currently the mainstream photoresist product in the world, and it is one of the key technologies for processing photo-etched integrated circuits and manufacturing chips.
使用
4-Acetoxystyrene is a stable Styrene monomer which can be readily polymerized and copolymerized to low, medium and high molecular weight polymers. Undergoes free radical polymerization, similar to styrene.
製法・合成法
製造方法
The preparation of 4-Acetoxystyrene is as follows:Add p-hydroxystyrene (120g) to a 2L four-neck bottle. triethylamine(106g), phenothiazine (1.2g), Methyl tert-butyl ether (480 g), Dry ice-ethanol bath to -5 to 0 °C, acetyl chloride (86g) was added dropwise with stirring. The internal temperature is controlled at -5 to 0 °C. After the completion of the dropwise addition, the temperature was raised at 10 to 20 °C to continue the reaction for 1 hour. Sampling analysis (central control 1, raw material After completion of the reaction, the mixture was filtered, and the cake was washed with methyl t-butyl ether (50 g × 3). The filtrate was quenched by the addition of 4 g of methanol, and the reaction was stirred for 10 minutes. After completion, phenothiazine (1.2 g) was added and the reaction mixture was concentrated.Methyl tert-butyl ether (580 g) was recovered to give a crude product (160 g).The crude product was distilled under reduced pressure to give the product, p-acetoxy styrene (142 g), yield 87.7%, and sampled for analysis (main content >99%).