6-アミノ-m-クレゾール

2-Amino-5-methylphenol

HCID 76082CAS 2835-98-5

基本情報

標準SMILES
Cc1ccc(N)c(O)c1
InChIKey
HCPJEHJGFKWRFM-UHFFFAOYSA-N
分子式
C7H9NO
平均分子量
123.15 g/mol
単同位体質量
123.06841391

名称と識別子

優先名称
2-Amino-5-methylphenol
IUPAC
2-amino-5-methylphenol
現地名
6-アミノ-m-クレゾール
英語名
6-Amino-m-cresol
分子式
C7H9NO
分子量
123.15

名称と別名

2-Amino-5-methylphenol6-Amino-m-cresol2835-98-52-Hydroxy-4-methylanilinePhenol, 2-amino-5-methyl-4-Amino-3-hydroxytolueneQCG4ES2A26NSC-322874DTXSID20182594RefChem:85284DTXCID60105085220-620-7
名称をさらに表示
6-アミノ-m-クレゾール2-ヒドロキシ-4-メチルアニリン2-アミノ-5-メチルフェノール5-メチル-2-アミノフェノール6-アミノ-m-クレゾル6アミノmクレゾ-ルJAROCOL 2M5AP6-amino-meta-cresol6-Amino-m-cresol,98%6-Amino-m-cresol >m-Hydroxy-p-toluidine6-Amino-m-methylphenol
Cetilistat Impurity 46-Amino-3-methylphenol6-AMINO-3-CRESOLMFCD000076935-methyl-2-aminophenolEINECS 220-620-7UNII-QCG4ES2A26NSC 322874

データベース識別子

CAS
2835-98-5
PubChem CID
76082
DTXSID
DTXSID20182594
UNII
QCG4ES2A26
EC Number
220-620-7
Nikkaji
J13.777D

物性

構造計算による物性

XLogP
1.2
極性表面積
46.3 Ų
水素結合供与体数
2
水素結合受容体数
2
回転可能結合数
0
重原子数
9

実験および物理化学的性質

Kovats Retention Index1634

物理化学的性質

融点
160 · 160-162 °C(lit.)
沸点
229.26 °C · 229.26°C (rough estimate)
比重(密度)
1.0877 · 1.0877 (rough estimate)
屈折率
1.538 · 1.5380 (estimate)
貯蔵温度
Keep in dark place,Sealed in dry,Room Temperature
溶解性
DMSO(微量)、メタノール(微量)

化学的性質

化学的特性Beige to brown crystal powder

安全と法規制

GHS分類

GHS Classification · 6 件

Warning

H302 (62.4%): Harmful if swallowed [Warning Acute toxicity, oral];H315 (89.9%): Causes skin irritation [Warning Skin corrosion/irritation];H317 (42.2%): May cause an allergic skin reaction [Warning Sensitization, Skin];H319 (89.9%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (89%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 109 reports by companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory Information · 2 件

Chemical: Phenol, 2-amino-5-methyl-

Phenol, 2-amino-5-methyl-: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Phenol, 2-amino-5-methyl-: Human health tier II assessment
Hazard Classes and Categories · 2 件

Acute Tox. 4 (62.4%);Skin Irrit. 2 (89.9%);Skin Sens. 1 (42.2%);Eye Irrit. 2A (89.9%);STOT SE 3 (89%)

Acute toxicity (ingestion) - category 4;Germ cell mutagenicity - category 2;Skin sensitisation - category 1A

毒性情報

Toxicity Summary · 2 件

The Expert Panel for Cosmetic Ingredient Safety concluded that the available data are insufficient to make a determination of safety for 6-Amino-m-Cresol under the intended conditions of use as a hair dye ingredient.

The available data are insufficient to support safety

法規制情報

Regulatory Information · 2 件

Chemical: Phenol, 2-amino-5-methyl-

Phenol, 2-amino-5-methyl-: Does not have an individual approval but may be used under an appropriate group standard

安全データ

wgk
1
rtecs
SJ6090000
hs_code
29222900
risk_code
36/37/38-20/21/22
化審法
(3)-707
hazard_code
Xi,Xn

化学と産業

用途と製造

UsesCIR ingredient: 6-Amino-m-Cresol
Use ClassificationCosmetics -> Hair dyeing
応用分野 · 3 件

用途有機合成原料。

使用2-Amino-5-methylphenol was used in the synthesis of tridentate Schiff base ligand and novel non-metallocene catalysts with phenoxy-imine ligands.

一般的な説明2-Amino-5-methylphenol reacts with bovine hemoglobin to form 2-amino-4,4α-dihydro-4α-7-dimethyl-3H-phenoxazine-3-one, which inhibits the proliferation of Poliovirus in Vero cells. It is converted to dihydrophenoxazinone by purified human hemoglobin.

調製方法

純化方法Crystallise it from H2O, 50% EtOH, or toluene. [Beilstein

サプライヤー50 社

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
杭州倍生元生物科技有限公司15700194842 15700194842
爱斯特(成都)生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

関連反応

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関連ノート

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