基本情報
- CAS
103-34-4- 標準SMILES
C1CN(SSN2CCOCC2)CCO1- InChIKey
HLBZWYXLQJQBKU-UHFFFAOYSA-N- 分子式
- C8H16N2O2S2
- 平均分子量
- 236.4 g/mol
- 単同位体質量
- 236.0653201
概要
rubber vulcanizing agent causing occupational dermatitis; structure
名称と識別子
- 優先名称
- Dtdm
- IUPAC
- 4-(morpholin-4-yldisulfanyl)morpholine
- 現地名
- 4,4'-ジチオジモルホリン
- 英語名
- 4,4'-Dithiodimorpholine
- 分子式
- C8H16N2O2S2
- 分子量
- 236.35
名称と別名
4,4'-DITHIODIMORPHOLINE103-34-4Morpholine, 4,4'-dithiobis-Morpholine disulfideAccel R4,4'-DithiomorpholineMorpholino disulfideDimorpholine disulfideDimorpholino disulfideDeovulc MSanfel RBismorpholino disulfide
名称をさらに表示
4,4'-ジチオジモルホリンジモルホリノペルジスルフィドビスモルホリノペルスルフィドジモルホリノペルスルフィド4,4'-ジチオビスモルホリンビス(モルホリン-4-イル)ペルスルフィドモルホリンジスルフィド4,4′-ジチオジモルホリンN,N′-二硫化ジモルホリンジチオジモルホリン４，４’ジチオジモルホリンN,N'-ジチオビス(モルホリン)N,N'-ジモルホリンジスルフィド4，4’-ジチオジモルホリン4,4′‐ジチオジモルホリン二硫化N,N'-ジモルホリンDTDM1,2-diMorpholinodisulfane4,4'-daccelrsanfelrdeovulcmusafb-17
DithiobismorpholineMorpholinodisulfideVanax ADisulfide, dimorpholino-Usaf ek-t-6645Usaf B-17Vulnoc4,4'-Dithiobismorpholine
物性
構造計算による物性
- XLogP
- 0.6
- 極性表面積
- 75.5 Ų
- 水素結合供与体数
- 0
- 水素結合受容体数
- 6
- 回転可能結合数
- 3
- 重原子数
- 14
- 形式電荷
- 0
- 複雑度
- 143
実験および物理化学的性質
Chemical ClassesNitrogen Compounds -> Morpholines
Density1.36 @ 25 °C
Color/Form
CRYSTALS
GRAY TO TAN POWDER
Flash Point
121 °C
250 °F (MINIMUM)
Melting Point125 °C
Vapor Pressure0.0000305 [mmHg]
Food Contact Substances
FCS -> FDA Cumulative Estimated Daily Intake (CEDI)
FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
Physical Description
Dry Powder; Large Crystals; Large Crystals; Dry Powder
Gray to tan solid; [Hawley] White solid; [MSDSonline]
物理化学的性質
- 融点
- 124 · 124-125°C
- 沸点
- 371.7 · 371.7±52.0 °C(Predicted)
- 比重(密度)
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
Warning
H315 (10.3%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P272, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 184 reports by companies from 12 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
危険有害性情報
Regulatory Information
Chemical: Morpholine, 4,4'-dithiobis-
Morpholine, 4,4'-dithiobis- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Morpholine, 4,4'-dithiobis- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: Di(morpholin-4-yl) disulphide (EC: 203-103-0)
Morpholine, 4,4'-dithiobis-: Does not have an individual approval but may be used under an appropriate group standard
Hazards Summary
Effects in high-dose feeding studies of rats include anemia and liver changes; Emergency treatment: Morpholine; Morpholine is an irritant that can cause corneal damage; Liver and kidney injury occur in lethal-dose studies of laboratory animals; [HSDB] Causes abnormal liver function tests in feeding studies of rats; [RTECS] Not irritating to skin but irritating to eyes in rabbits; Not sensitizing; Decrease in fetal viability and body weight, and minor increase in malformed fetuses at materno-toxic doses; Not mutagenic; [EPA Hazard Characterization Document] Irritating but not sensitizing in patch test with ten volunteers; [EPA HPVIS] May cause irritation; [Aldrich MSDS]
Hazard Classes and CategoriesSkin Irrit. 2 (10.3%)
Explosive Limits and Potential
化学と産業
用途と製造
Uses
Used as a stain protector for rubber, a vulcanizer (sulfur donor) and accelerator for natural and synthetic rubbers, a fungicide, and a curing agent for poly(fluoroalkoxyphosphazenes); [HSDB]
Farming (Pesticides) [Category: Industry]
STAINING PROTECTOR IN RUBBER; IN VULCANIZATION OF RUBBER; FUNGICIDE
ORGANOSULFUR ACCELERATOR
ACCELERATOR FOR NATURAL & SYNTHETIC RUBBERS
VULCANIZER (SULFUR DONOR) FOR NATURAL & SYNTHETIC RUBBERS
U.S. Exports
(1979) No Data
(1981) No Data
U.S. Imports
(1979) No Data
(1981) No Data
U.S. Production
2023: 550,000 - <700,000 lb
(1979) PROBABLY GREATER THAN 4.54X10+5 GRAMS
(1981) PROBABLY GREATER THAN 4.54X10+5 GRAMS
Consumer UsesNot Known or Reasonably Ascertainable
Industry UsesOther
Methods of Manufacturing
BLAKE, J AM CHEM SOC 65, 1267 (1943); BLAKE, US PATENT 2,343,524 (1944 TO MONSANTO); HARMAN, US PATENT 2,766,236 AND BRITISH PATENT 774,570 (1956, 1957, BOTH TO MONSANTO). LAMBRECH ET AL, US PATENT 2,902,402 (1959 TO PFIZER). ... AS FUNGICIDE: LADD, US PATENT 2,429,097 (1949 TO US RUBBER).
OXIDATIVE COUPLING OF 4-THIOMORPHOLINE WITH MOLECULAR OXYGEN IN THE PRESENCE OF AN AQUEOUS CAUSTIC AGENT & CATALYST
General Manufacturing Information
Wholesale and Retail Trade
Morpholine, 4,4'-dithiobis-: ACTIVE
調製方法
Crystallise it from hot aqueous dimethylformamide or EtOH. It is a fungicide. [Blake J Am Chem Soc 65 1267 1943.]
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