化工社化工社 化学情報印刷レポート · 研究参考用
クロロメチルメチルエーテル
クロロメチルメチルエーテル · クロロメチルラジカル · クロロジメチルエ-テル · クロロジメチルエーテル · クロロメチルメチルエテル · クロロメチルメチルエーテル（CMME） · CH3OCH2Cl · chloromethyl
識別子と物理属性
| CAS No. | 107-30-2 |
|---|---|
| 分子式 | C2H5ClO |
| 平均分子量 | 80.51 g/mol |
| 単同位体質量 | 80.00289246 g/mol |
| SMILES | COCCl |
| InChIKey | XJUZRXYOEPSWMB-UHFFFAOYSA-N |
| PubChem CID | 7864 |
| ChEMBL | CHEMBL3185256 |
| ChEBI | CHEBI:82271 |
| EC No. | 203-480-1 |
| DTXSID | DTXSID6020307 |
| 現地名 | クロロメチルメチルエーテル |
化学・物理的性質
| XLogP | 0.8 |
|---|---|
| 極性表面積 | 9.2 |
| 水素結合供与体数 | 0 |
| 水素結合受容体数 | 1 |
| 回転可能結合数 | 1 |
| 重原子数 | 4 |
| 形式電荷 | 0 |
| 複雑度 | 10 |
| 物質分類 | Hazardous Air Pollutants (HAPs)Other Classes -> Halogenated EthersCarcinogens |
| SpringerMaterials Properties | Schoenflies notation |
| 農薬 | Pesticide -> EPA IRIS |
| LogP（分配係数） | 0.320 |
| 臭い | Irritating odorIrritating odor. |
| 食品添加物 | PROCESSING AID -> FDA Substance added to food |
| 密度 | 1.0605 at 68 °F (EPA, 1998) - Denser than waterwill sink1.0603 @ 20 °C/4 °CRelative density (water = 1): 1.061.063 @ 10°C1.06 g/mL at 25 °C(lit.) |
| Color/Form | COLORLESS LIQColorless liquid. |
| 溶解度 | Reacts with water (NIOSH, 2024)MISCIBLE WITH ETHANOL & ETHER & MANY OTHER ORG SOLVENTSSOL IN ACETONE, CHLOROFORM, ETHYL ETHER, ETHYL ALCOHOLSoluble in oxygenated solventsSolubility in water: decomposes分解する |
| Corrosivity | Will react with surface moisture to evolve hydrogen chloride which is corrosive to metal. |
| 引火点 | 32 °F (EPA, 1998)0 °C0 °C (open cup).-8 °C c.c.32 °F (open cup)(oc) 32 °F60 °F |
| 沸点 | 138 °F at 760 mmHg (EPA, 1998)59.5 °C59.00 to 60.00 °C. @ 760.00 mm Hg59 °C59.5 °C @760 [mm Hg]55-57 °C(lit.) |
| 融点 | -103°C |
| 蒸気圧 | 3.55 psi ( 20 °C) |
| 屈折率 | n20/D 1.396(lit.) |
| 貯蔵条件 | 0-6°C |
| Merck | 13,2165 |
| CAS データベース | 107-30-2(CAS DataBase Reference) |
| NISTの化学物質情報 | Methane, chloromethoxy-(107-30-2) |
化学的特性
Clear Colourless Oil
安全性と法規制
| GHS 分類 | DangerH225: Highly Flammable liquid and vapor [Danger Flammable liquids]P203, P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P317, P318, P321, P330, P362+P364, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]P203, P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P317, P318, P321, P330, P337+P317, P362+P364, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement) |
|---|---|
| Hazards Identification | Toxic/poison by inhalation (TIH/PIH) |
| 規制情報 | Chemical: Methane, chloromethoxy-Hazard Traits - CarcinogenicityDermatotoxicityOcular ToxicityRespiratory ToxicityMethane, chloromethoxy- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Methane, chloromethoxy- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Chloromethyl methyl ether: HSNO Approval: HSR002938 Approved with controlsThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| その他の安全情報 | IMAP assessments - Methane, chloromethoxy-: Environment tier I assessment |
| 輸送ラベル（DOT） | Poison Inhalation Hazard Flammable Liquid |
| 火災危険 | Flammable/combustible materialmay be ignited by heat, sparks, or flames. Vapors may travel to a source of ignition and flash back. Container may explode in heat of fire. In addition to the risk of explosion, when air mixtures of ether vapors are heated or exposed to flame or sparks, they tend to form peroxides. Ethers containing peroxides can detonate when heated. Unburned material may form powerful tear gas. When wet, also forms irritating formaldehyde gas. Evolves formaldehyde and hydrogen chloride. When heated to decomposition, it emits toxic fumes of chlorides. Avoid decomposing heat Hazardous polymerization may not occur. (EPA, 1998) |
用途
使用
A chloroalkyl ether that is an efficient alkylating agent. Used as an alcohol protecting group in the preparation of various organic compounds. A known human carcinogen.
一般的な説明
A clear colorless liquid. Flash point -4°F. Irritates the eyes and respiratory system. Very toxic by inhalation and may be toxic by ingestion or skin absorption. Vapors are heavier than air.