CAS 2247-88-3 4-Amino-3-fluoropyridine (HCID 817122)

名称と識別子

優先名称: 4-Amino-3-fluoropyridine
IUPAC: 3-fluoropyridin-4-amine
現地名: 4-アミノ-3-フルオロピリジン
英語名: 4-Amino-3-fluoropyridine
分子式: C5H5FN2
分子量: 112.11

名称と別名

4-Amino-3-fluoropyridine2247-88-34-Pyridinamine, 3-fluoro-Y744OES4EPPyridine, 4-amino-3-fluoro-DTXSID70355751UNII-Y744OES4EPRefChem:97739DTXCID80306810623-648-13-fluoropyridin-4-amine3-fluoro-4-aminopyridine

名称をさらに表示

4-アミノ-3-フルオロピリジン3-フルオロピリジン-4-アミン4-Aminfluoropyridin-4-amine4-AMINO-3-FLUOROPYRINE3-Fluoro-4-pyridinamine3-fluoropyridin-4-amine 97%4-Amino-3-fluoropyridine >

3-Fluoro-pyridin-4-ylamineMFCD002340724-amino-3-fluoro-pyridine4-Amino-3-fluoropyridine, 97%CL0178CS-W007902EN300-853503-Amine-5-fluoropyridine

データベース識別子

CAS: 2247-88-3
PubChem CID: 817122
DTXSID: DTXSID70355751
UNII: Y744OES4EP
EC Number: 623-648-1
Nikkaji: J3.593.116C

物性

構造計算による物性

XLogP: 0.3
極性表面積: 38.9 Å²
水素結合供与体数: 1
水素結合受容体数: 3
回転可能結合数: 0
重原子数: 8
形式電荷: 0
複雑度: 76

物理化学的性質

融点: 71 · 71-79 °C
沸点: 217.1 · 217.1±20.0 °C(Predicted)
比重(密度): 1.257 · 1.257±0.06 g/cm3(Predicted)
貯蔵温度: Keep in dark place,Inert atmosphere,Room temperature
溶解性: soluble in Methanol
外見: powder to crystal
酸解離定数(Pka): 7.19 · 7.19±0.12(Predicted)
色: White to Light yellow to Light orange
InChI: InChI=1S/C5H5FN2/c6-4-3-8-2-1-5(4)7/h1-3H,(H2,7,8)
InChIKey: UFIKBUVVVGSMGW-UHFFFAOYSA-N
SMILES: C1=NC=CC(N)=C1F
CAS データベース: 2247 · 2247-88-3(CAS DataBase Reference)

化学的性質

化学的特性Yellow to light yellow crystals

安全と法規制

GHS分類

GHS Classification · 5 件

Warning

H302 (89.1%): Harmful if swallowed [Warning Acute toxicity, oral]；H312 (10.9%): Harmful in contact with skin [Warning Acute toxicity, dermal]；H315 (15.2%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (13%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 46 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Hazard Classes and CategoriesAcute Tox. 4 (89.1%)；Acute Tox. 4 (10.9%)；Skin Irrit. 2 (15.2%)；Eye Irrit. 2A (100%)；STOT SE 3 (13%)

安全データ

wgk: nwg
hs_code: 29333990
risk_code: 22-36
hazard_code: Xi,Xn
hazard_note: Irritant
safety_code: 26
hazard_class: 6.1
Hazard Classifications: Acute Tox. 4 OralEye Irrit. 2
ストレージクラス: 11 - Combustible Solids

化学と産業

応用分野

使用4-Amino-3-fluoropyridine is an important intermediate in the synthesis of many new drugs, and it is an intermediate in the synthesis of transforming growth factor-β inhibitors and thrombin inhibitors.

上流・下流製品情報

上流原料

オキシドールクロロホルム 3-フルオロピリジン硝酸酢酸硫酸鉄(II)·7水和物硫酸水素アンモニア 3-フルオロピリジン1-オキシド 3-フルオロ-4-ニトロピリジンN-オキシド 3-ブロモ-4-ニトロピリジンN-オキシド

下流製品

3-フルオロ-4-ヒドロキシピリジン tert-Butyl 3-fluoropyridin-4-ylcarbamate

サプライヤー100 社

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

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爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

上海赫文斯化工有限公司15721252604 17321035817 · [email protected]

化合物ノート

読み込み中…

4-アミノ-3-フルオロピリジン

基本情報