2-Anisidine hydrochloride

HCID 8638CAS 134-29-2

部分構造検索類似構造を探す

基本情報

標準SMILES: COc1ccccc1N.Cl
InChIKey: XCZCWGVXRBJCCD-UHFFFAOYSA-N
分子式: C7H9NO.ClH
平均分子量: 159.61 g/mol
単同位体質量: 159.04509162

概要

o-Anisidine Hydrochloride can cause cancer according to an independent committee of scientific and health experts.

名称と識別子

優先名称: 2-Anisidine hydrochloride
IUPAC: 2-methoxyaniline;hydrochloride

名称と別名

2-Anisidine hydrochlorideRefChem:167141134-29-22-Methoxyaniline hydrochlorideO-ANISIDINE HYDROCHLORIDEo-Anisidine.HClFast Red BB Base2-Methoxyaniline HClBenzenamine, 2-methoxy-, hydrochlorideO-Anisidine HClo-Anisidine, hydrochlorideo-Methoxyaniline hydrochloride

名称をさらに表示

2-Methoxybenzenamine hydrochlorideMFCD000543342-methoxyaniline;hydrochlorideDTXSID8020092C.I. 37115Anisidine hydrochloride, o-74SDU6V9SCDTXCID3092

データベース識別子

CAS: 134-29-2
PubChem CID: 8638
DTXSID: DTXSID8020092
ChEMBL: CHEMBL3183318
UNII: 74SDU6V9SC
EC Number: 603-807-1

物性

構造計算による物性

極性表面積: 35.3 Å²
水素結合供与体数: 2
水素結合受容体数: 2
回転可能結合数: 1
重原子数: 10
形式電荷: 0
複雑度: 85

実験および物理化学的性質

Chemical ClassesCarcinogens

Solubility10 to 50 mg/mL at 70 °F (NTP, 1992)

Melting Point437 to 441 °F (NTP, 1992)

Physical DescriptionO-anisidine hydrochloride appears as gray-black crystalline solid or light gray powder. May be carcinogenic.

安全と法規制

GHS分類

GHS Classification · 6 件

Danger

H301+H311+H331 (50%): Toxic if swallowed, in contact with skin or if inhaled [Danger Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]

P203, P260, P261, P262, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P308+P316, P316, P318, P319, P321, P330, P337+P317, P361+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H341: Suspected of causing genetic defects [Warning Germ cell mutagenicity]

危険有害性情報

Regulatory Information · 2 件

Hazard Traits - Carcinogenicity

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

Fire HazardsFlash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)

Health HazardsSYMPTOMS: This compound may cause local irritating effects to the eyes, mucous membranes and skin. It may also cause allergic responses.

Reactive GroupEthers

Reactivity Profile · 1 件

O-ANISIDINE HYDROCHLORIDE reacts as an acid to neutralize bases. These neutralizations generate some heat. Usually does not react as either an oxidizing agent or reducing agent but such behavior is not impossible. May catalyze organic reactions.

Air and Water ReactionsWater soluble.

安全と保護具

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

First Aid · 1 件

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 件

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE)MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.

毒性情報

Carcinogen Classification · 6 件

ortho-Anisidine hydrochloride

Group 2A: Probably carcinogenic to humans

Volume 127: (2021) Some Aromatic Amines and Related Compounds

2021 online

2020

o-Anisidine hydrochloride

RAIS Toxicity Values · 4 件

3.1e-05

CALEPA

0.11