N-(2-アミノエチル)ピペラジン
N-(2-アミノエチル)ピペラジン · 2-ピペラジノエタンアミン · 1-ピペラジンエタン-1-アミン · 1-(2-アミノエチル)ピペラジン · 1-ピペラジンエタンアミン · 2-(ピペラジン-1-イル)エタンアミン · 2-ピペラジノエチルアミン · ピペラジン-1-エタンアミン
識別子と物理属性
| CAS No. | 140-31-8 |
|---|---|
| 分子式 | C6H15N3 |
| 平均分子量 | 129.2 g/mol |
| 単同位体質量 | 129.12659748 g/mol |
| SMILES | NCCN1CCNCC1 |
| InChIKey | IMUDHTPIFIBORV-UHFFFAOYSA-N |
| PubChem CID | 8795 |
| ChEMBL | CHEMBL209790 |
| EC No. | 205-411-0 |
| DTXSID | DTXSID2021997 |
| 現地名 | N-(2-アミノエチル)ピペラジン |
化学・物理的性質
| XLogP | -1.3 |
|---|---|
| 極性表面積 | 41.3 |
| 水素結合供与体数 | 2 |
| 水素結合受容体数 | 3 |
| 回転可能結合数 | 2 |
| 重原子数 | 9 |
| 形式電荷 | 0 |
| 複雑度 | 68.7 |
| 物質分類 | Nitrogen Compounds -> PiperazinesCorrosives |
| SpringerMaterials Properties | Boiling point |
| 密度 | 0.9852 at 68 °F (USCG, 1999) - Less dense than waterwill float0.985 g/cu cm at 25 °C0.985 @25 °C0.985 g/mL at 25 °C(lit.) |
| Color/Form | Light-colored liquid |
| 溶解度 | Soluble in water>1000g/l溶ける |
| 引火点 | 200 °F (USCG, 1999)93 °C200 °F (93 °C) open cup |
| 沸点 | 428 °F at 760 mmHg (USCG, 1999)220 °C222 °C @760 [mm Hg]218-222 °C(lit.) |
| Decomposition | When heated to decomposition it emits toxic fumes of /nitric oxides/. |
| 融点 | -2 °F (USCG, 1999)FP: 17.6 °C-20 °C-19 °C |
| 蒸気密度 | 4.4 (Air = 1)4.4 (vs air) |
| 臭気閾値 | Odor Threshold Low: 0.1 [ppm] |
| 蒸気圧 | 0.04 [mmHg]0.04 [mm Hg] @20 °C0.05 mm Hg ( 20 °C) |
| 屈折率 | n20/D 1.500 |
| 貯蔵条件 | Store below +30°C. |
| 外観・状態 | 液体 |
| pKa（酸解離定数） | 10.11±0.10(Predicted) |
| 色 | 無色透明～微黄色透明 |
| pH | 12 (100g/l, H2O, 20℃) |
| 爆発限界 | 2.1-10.5%(V) |
| BRN | 104363 |
| ヘンリー定数 | 1.5×107 mol/(m3Pa) at 25℃, HSDB (2015) |
| 安定性 | 安定。可燃性。酸、酸無水物、酸塩化物、強力な酸化剤、クロロホルメートとは混和しません。 |
| InChI | 1S/C6H15N3/c7-1-4-9-5-2-8-3-6-9/h8H,1-7H2 |
| InChIKey | IMUDHTPIFIBORV-UHFFFAOYSA-N |
| SMILES | NCCN1CCNCC1 |
| LogP（分配係数） | -1.48 at 20℃ |
| CAS データベース | 140-31-8(CAS DataBase Reference) |
| NISTの化学物質情報 | N-(2-Aminoethyl)piperazine(140-31-8) |
| EPAの化学物質情報 | 1-Piperazineethanamine (140-31-8) |
化学的特性
N-Aminoethypiperazine is a combustible and corrosive aliphatic amine. It is a colorless to light yellow viscous liquid.
安全性と法規制
| GHS 分類 | DangerH302: Harmful if swallowed [Warning Acute toxicity, oral]P260, P261, P264, P270, P272, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P333+P317, P362+P364, P363, P405, and P501 (click each P-code to see the statement)H302 (94.3%): Harmful if swallowed [Warning Acute toxicity, oral]P260, P261, P262, P264, P264+P265, P270, P272, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P333+P317, P361+P364, P362+P364, P363, P405, and P501 (click each P-code to see the statement) |
|---|---|
| 規制情報 | Chemical: 1-Piperazineethanamine1-Piperazineethanamine is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1-Piperazineethanamine are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 15-12-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/16054The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| 輸送ラベル（DOT） | Corrosive Poison |
| 火災危険 | Special Hazards of Combustion Products: Toxic fumes of NO x (USCG, 1999)· Combustible material: may burn but does not ignite readily. |
| 健康有害性 | INHALATION: Burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting. EYES AND SKIN: Extremely destructive to mucous membranes, upper respiratory tract, eyes and skin. Causes burns on short contact. (USCG, 1999)· TOXIC and/or CORROSIVEinhalation, ingestion or skin contact with material may cause severe injury or death. |
| 有害性の概要 | Liquid causes second or third degree burns after short contact. [CHRIS] Pulmonary edema may result from inhalation of high concentrations. [NJ-HSFS] Can cause coughing, wheezing, and shortness of breath if inhaled[CAMEO] |
| 輸送番号・ガイド（DOT） | 2815 153 |
| 反応性グループ | Amines, Phosphines, and Pyridines |
用途
用途
エポキシ硬化剤、腐食防止剤、合成中間体(染料、界面活性剤、各種医薬品)
使用
Used for studying corrosion inhibition
一般的な説明
N-aminoethylpiperazine appears as a colorless liquid with a faint fishlike odor. Flash point 199 °F. Corrosive to tissue. Toxic oxides of nitrogen are produced by combustion.
製法・合成法
製造方法
he synthesis of N-(2-aminoethyl) piperazine from PZ and MEA in the presence of CO2 was conducted using a method similar to that of thermal degradation experiments. 7 m PZ/2 m MEA with 0.3 mol CO2 /mol alkalinity was placed in -inch OD 316 stainless steel thermal cylinders , which were then sealed and placed in a convection oven held at 150 °C. Cylinders were removed periodically and samples were analyzed using ion chromatography.