Carbamol (HCID 8827)

概要

Oxymethurea is a member of ureas.

名称と識別子

優先名称: Carbamol
IUPAC: 1,3-bis(hydroxymethyl)urea
現地名: 1,3-(ヒドロキシメチル)尿素
英語名: Dimethylolurea
分子式: C3H8N2O3
分子量: 120.11

名称と別名

1,3-Bis(hydroxymethyl)ureaN,N'-Bis(hydroxymethyl)ureaCarbamolRefChem:857848Dimethylolurea140-95-4OxymethureaN,N'-DimethylolureaMethuralProtesine DMU1,3-DimethylolureaMetural

名称をさらに表示

1,3-(ヒドロキシメチル)尿素ニテックスASLフィニッシュENメツラルプロテシンDMUCSIパステメツラールオキシメトウレアクニテックスASLジメチロール尿素N,N'-ジ(ヒドロキシメチル)尿素1,3-ビス(ヒドロキシメチル)尿素パーマフレッシュ477ウレオールPN,N'-ジメチロール尿素N,N'-ビス(ヒドロキシメチル)尿素1,3-ジ(ヒドロキシメチル)尿素N,N'-ジメチロ-ルウレアN,N′-ビス(ヒドロキシメチル)尿素N,N′-ジメチロール尿素Methurin

Urea, N,N'-bis(hydroxymethyl)-Finish ENKnittex ASLUreol PCSI PasteCauriteUrofixKaurit S

データベース識別子

CAS: 140-95-4
PubChem CID: 8827
DTXSID: DTXSID6025141
ChEMBL: CHEMBL3185052
ChEBI: CHEBI:134755
UNII: N68H97CAWG
EC Number: 205-444-0
Nikkaji: J10.647J

物性

構造計算による物性

XLogP: -1.8
極性表面積: 81.6 Å²
水素結合供与体数: 4
水素結合受容体数: 3
回転可能結合数: 2
重原子数: 8
形式電荷: 0
複雑度: 66.9

実験および物理化学的性質

Chemical ClassesOther Uses -> Biocides/Disinfectants

SpringerMaterials Properties15N nuclear magnetic resonance spectrum

Vapor Pressure0.00000399 [mmHg]

Physical DescriptionLiquid

Collision Cross Section151.7 Å² [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID6025141]

物理化学的性質

融点: 125 °C · 125 °C (dec.)(lit.)
沸点: 224.08 °C · 224.08°C (rough estimate)
比重(密度): 1.34 · 1.34
屈折率: 1.461 · 1.4610 (estimate)
闪点: 100 °C · 100 °C
貯蔵温度: 2 · 2-8°C
酸解離定数(Pka): 12.14 · 12.14±0.46(Predicted)
外見: powder to crystal
色: White to Almost white
水溶解度: 150 g/リットル · 150g/リットル
Merck: 14 · 14,6968
BRN: 1811870 · 1811870
化粧品成分の機能: 抗菌剤
InChI: 1S/C3H8N2O3/c6-1-4-3(8)5-2-7/h6-7H,1-2H2,(H2,4,5,8)
InChIKey: QUBQYFYWUJJAAK-UHFFFAOYSA-N
SMILES: OCNC(=O)NCO
LogP: -2.61 · -2.610 (est)
CAS データベース: 140 · 140-95-4(CAS DataBase Reference)
NISTの化学物質情報: Dimethanolurea(140-95-4)
EPAの化学物質情報: Dimethylolurea (140-95-4)

化学的性質

化学的特性white powder

安全と法規制

GHS分類

GHS Classification · 5 件

This chemical does not meet GHS hazard criteria for 48.4% (104 of 215) of reports.

Warning

H319 (51.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)

Aggregated GHS information provided per 215 reports by companies from 7 notifications to the ECHA C&L Inventory.

危険有害性情報

Regulatory Information · 4 件

Chemical: Urea, N,N'-bis(hydroxymethyl)-

Urea, N,N'-bis(hydroxymethyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Urea, N,N'-bis(hydroxymethyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

REACH registered substance: 1,3-bis(hydroxymethyl)urea (EC: 205-444-0)

Carbamol: Does not have an individual approval but may be used under an appropriate group standard

Hazards Summary · 1 件

A formaldehyde releaser, dimethylol urea can cause allergic contact dermatitis in workers handling durable press chemical finishes used on fabrics for wrinkle resistance; Cases were reported in the 1950s before the textile industry started using finishes releasing less formaldehyde; [Kanerva, p. 397-408]

Hazard Classes and CategoriesEye Irrit. 2 (51.2%)

毒性情報

Adverse EffectsSkin Sensitizer - An agent that can induce an allergic reaction in the skin.

安全データ

wgk: 3
tsca: TSCA listed
rtecs: YS2716350
hs_code: 29241990
risk_code: 45
化審法: (2)-1739
hazard_code: T
safety_code: 24/25-45-53
Hazard Classifications: Eye Irrit. 2
ストレージクラス: 13 - Non Combustible Solids

化学と産業

用途と製造

Uses · 2 件

Used in the production of urea-formaldehyde resins and as a textile finish; [Kanerva, p. 405]

Using Disinfectants or Biocides [Category: Clean]

U.S. Production2023: 75,000 - <500,000 lb

Industry UsesIntermediate

General Manufacturing Information · 2 件

Wood Product Manufacturing

Urea, N,N'-bis(hydroxymethyl)-: ACTIVE

応用分野

使用In the textile industry in cotton crease- and shrink-proofing, finishing, drying, sizing; in tanning; pesticides; in photographic developers.

調製方法 · 2 件

Dimethylolurea is produced industrially by the addition of 2 mol of formaldehyde per mole of urea in a stirred vessel. The solution is neutralized with triethanolamine. Urea is added with cooling, and the temperature must not exceed 40 ℃ in this slightly exothermic reaction. After a few hours, the reaction mixture is cooled to room temperature and dihydroxymethylurea crystals form upon cooling. The product is dried in a spray-drying tower.

純化方法Crystallise it from aqueous 75% EtOH. [Beilstein 3 IV 107.]

上流・下流製品情報

上流原料

ホルマリン尿素トリエタノールアミン

下流製品

1-(ヒドロキシメチル)尿素ホルマリン

サプライヤー50 社

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

湖北永阔科技有限公司027-59223108 15972152991 · [email protected]

Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]

湖北万得化工有限公司15377098680 15377098680 · [email protected]

成都彼样生物科技有限公司18108052721 · [email protected]

1,3-(ヒドロキシメチル)尿素

基本情報

概要