基本情報
- CAS
142-58-5- 標準SMILES
CCCCCCCCCCCCCC(=O)NCCO- InChIKey
JHIXEZNTXMFXEK-UHFFFAOYSA-N- 分子式
- C16H33NO2
- 平均分子量
- 271.44 g/mol
- 単同位体質量
- 271.2511293
概要
N-(tetradecanoyl)ethanolamine is an N-(long-chain-acyl)ethanolamine resulting from the formal condensation of the carboxy group of tetradecanoic acid (myristic acid) with the amino group of ethanolamine. It is a N-(long-chain-acyl)ethanolamine and a N-(saturated fatty acyl)ethanolamine. It is functionally related to a tetradecanoic acid.
名称と識別子
- 優先名称
- N-Myristoylethanolamine
- IUPAC
- N-(2-hydroxyethyl)tetradecanamide
- 現地名
- N-(2-ヒドロキシエチル)テトラデカンアミド
- 英語名
- N-(2-hydroxyethyl)myristamide
- 分子式
- C16H33NO2
- 分子量
- 271.44
名称と別名
142-58-5N-(2-HYDROXYETHYL)TETRADECANAMIDEN-myristoylethanolamineComperlan MMTetradecanamide, N-(2-hydroxyethyl)-Loramine MY 228Schercomid MMEMyristyl monoethanolamideMyristoyl monoethanolamide6CYG57WXZ0Monoethanolamine myristic acid condensateDTXSID0042452
名称をさらに表示
N-ミリストイルエタノールアミンN-(2-ヒドロキシエチル)テトラデカンアミドN-(2-ヒドロキシエチル)ミリスチン酸アミドN-(2-ヒドロキシエチル)ミリストアミドミリスチン酸モノエタノールアミドN-ミリストイルエタノールアミドAM-3165N-(2-Hydroxyethyl)myristamidN-(tetradecanoyl)ethanolamineMyristic acid monoethanolamideN-(2-Hydroxyethyl)myristic amide
RefChem:825500DTXCID8022452N-(2-Hydroxyethyl)myristamidemyristoyl ethanolamideMyristic monoethanolamideMyristamide MEAMyristoyl-EAMyristoyl-ethanolamine
データベース識別子
- CAS
142-58-5- PubChem CID
- 8890
- DTXSID
DTXSID0042452- ChEMBL
CHEMBL5277451- ChEBI
CHEBI:85262- UNII
- 6CYG57WXZ0
- EC Number
- 205-546-5
- Nikkaji
- J115.314E
物性
構造計算による物性
- XLogP
- 5.1
- 極性表面積
- 49.3 Ų
- 水素結合供与体数
- 2
- 水素結合受容体数
- 2
- 回転可能結合数
- 14
- 重原子数
- 19
- 形式電荷
- 0
- 複雑度
- 195
実験および物理化学的性質
Chemical ClassesNitrogen Compounds -> Other Nitrogen Compounds
LipidsFatty Acyls [FA] -> Fatty amides [FA08] -> N-acyl ethanolamines (endocannabinoids) [FA0804]
Cosmetics
Cosmetic ingredients (Myristamide MEA) -> CIR (Cosmetic Ingredient Review)
Personal care product
Viscosity controlling; Foam boosting; Antistatic
Physical DescriptionOther Solid
物理化学的性質
- 融点
- 93 · 93-94 °C
- 沸点
- 436.3 · 436.3±28.0 °C(Predicted)
- 比重(密度)
- 0.916 · 0.916±0.06 g/cm3(Predicted)
- 貯蔵温度
- Sealed in dry,Room Temperature
- 溶解性
- 20 mg/ml; · DMF: 20 mg/ml; DMSO: 10 mg/ml; Ethanol: 1 mg/ml
- 外見
- A crystalline solid
- 酸解離定数(Pka)
- 14.49 · 14.49±0.10(Predicted)
- 化粧品成分の機能
- 帯電防止界面活性剤 - 泡立ち促進剤粘度制御
- LogP
- 4.777 · 4.777 (est)
- EPAの化学物質情報
- Tetradecanamide, N-(2-hydroxyethyl)- (142-58-5)
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
This chemical does not meet GHS hazard criteria for 33.3% (1 of 3) of reports.
Danger
H318 (66.7%): Causes serious eye damage [Danger Serious eye damage/eye irritation]
P264+P265, P280, P305+P354+P338, and P317 (click each P-code to see the statement)
Aggregated GHS information provided per 3 reports by companies from 3 notifications to the ECHA C&L Inventory.
危険有害性情報
Regulatory Information
Tetradecanamide, N-(2-hydroxyethyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Tetradecanamide, N-(2-hydroxyethyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Tetradecanamide, N-(2-hydroxyethyl)-: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesEye Dam. 1 (66.7%)
毒性情報
Toxicity Summary
The CIR Expert Panel concluded that the ethanolamides listed subsequently are safe in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating. The Expert Panel cautioned that these ingredients should not be used in cosmetic products in which N-nitroso compounds may be formed...Myristamide MEA
Safe for use in cosmetics, with qualifications
安全データ
- tsca
- TSCA listed
- 有毒物質データの
- 142-58-5(Hazardous Substances Data)
化学と産業
用途と製造
Uses
CIR ingredient: Myristamide MEA
Used as foam stabilizer and rinse improver for detergents, an opacifier in cosmetics, a corrosion inhibitor, a mold release agent, and an intermediate for sulfated and ethoxylated derivatives for detergents; [HSDB]
FOAM STABILIZER & RINSE IMPROVER FOR DETERGENT PRODUCTS
CHEM INT FOR SULFATED & ETHOXYLATED DERIVS FOR DETERGENTS
COSMETIC INGREDIENT (ESP AS AN OPACIFIER)
CORROSION INHIBITOR
U.S. Exports
(1979) No Data
(1981) No Data
U.S. Imports
(1979) No Data
(1981) No Data
U.S. Production
2023: 75,000 - <500,000 lb
(1979) AT LEAST 9.1X10+6 G-MIXT WITH C12 AMIDE
(1981) AT LEAST 6.8X10+6 G-MIXT WITH C12 AMIDE
Consumer UsesSurfactant (surface active agent)
Industry UsesSurfactant (surface active agent)
Methods of ManufacturingREACTION OF TETRADECANOIC ACID, COCONUT OIL ACIDS, OR THEIR METHYL ESTERS WITH 2-AMINOETHANOL IN A 1:1 RATIO (SODIUM METHYLATE MAY BE USED AS A CATALYST)
Use ClassificationCosmetics -> Viscosity controlling; Foam boosting; Antistatic
General Manufacturing Information
Soap, Cleaning Compound, and Toilet Preparation Manufacturing
Tetradecanamide, N-(2-hydroxyethyl)-: ACTIVE
上流・下流製品情報
下流製品
サプライヤー26 社
北京华美互利生物化工010-56205725 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
宜昌众意泰贸易有限公司0717-6449896 13886658719 · [email protected]
北京索莱宝科技有限公司010-50973130 17801761073 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
天津狄克特科技有限公司22-58627059 13920586291 · [email protected]
Alfa Chemistry1-516-6625404 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
陕西缔都医药化工有限公司029-029-81120477 17792793610 · [email protected]
陕西缔都医药化工有限公司+86-29-81139210 +86-17392587031 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
河北贞佳新材料有限公司0319-5925599 13315915972 · [email protected]
Shanghai Acmec Biochemical Technology Co., Ltd.+86-18621343501 · [email protected]
Shanghai Daken Advanced Materials Co.,Ltd+86-2158073036 · [email protected]
江苏艾康生物医药研发有限公司025-58859352 15955137747 · [email protected]
上海易恩化学技术有限公司400-400-1332688 18019345275 · [email protected]
上海宏叶生物科技有限公司400-9205774 400-920-5774 · [email protected]
河南威梯希化工科技有限公司0371-63284658 18135795563 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
SHANGHAI KEAN TECHNOLOGY CO., LTD.+8613817748580 · [email protected]
上海鼎芬化学科技有限公司021-57450129 17701764569 · [email protected]
佛山合硕医药科技有限公司15363639686 · [email protected]
上海易恩化学技术有限公司400-1332688 18019345275 · [email protected]
合肥钼凯医药科技有限公司18001872185; 18001872185 · [email protected]
上海皓鸿生物医药科技有限公司400-8210725 4008210725 · [email protected]
補足説明
定義ChEBI: An N-(long-chain-acyl)ethanolamine resulting from the formal condensation of the carboxy group of tetradecanoic acid (myristic acid) with the amino group of ethanolamine.
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