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アジピン酸ピペラジン

Piperazine Adipate

HCID 8905
ノート反応
基本情報概要名称と識別子物性安全と法規制化学と産業関連反応化合物ノート
部分構造検索類似構造を探す

基本情報

CAS
142-88-1
標準SMILES
C1CNCCN1.O=C(O)CCCCC(=O)O
InChIKey
BVEGEKOBSPXUJS-UHFFFAOYSA-N
分子式
C6H10O4.C4H10N2
平均分子量
232.28 g/mol
単同位体質量
232.14230712

概要

Piperazine adipate appears as odorless white crystalline powder or solid. Slightly acid taste. Melting point 256-257 °C. Dissolves slowly. pH (0.2-0.01 molar aqueous solutions) 5.45. pH (5% solution) 5 - 6. (NTP, 1992)

名称と識別子

優先名称
Piperazine Adipate
IUPAC
hexanedioic acid;piperazine
現地名
アジピン酸ピペラジン
英語名
PIPERAZINE ADIPATE
分子式
C10H20N2O4
分子量
232.28

名称と別名

Piperazine adipate142-88-1AdiprazinaAdiprazineVermicomprenArduverminHelmirazinPiperascatPiperaskatDietelminNometanOxurasin
名称をさらに表示
アジピン酸ピペラジンヘキサン二酸/ピペラジン,(1:1)ピペラジン·アジピン酸ピペラジン アジピン酸塩ピペラジンアジピン酸塩ピペラジンアジピン酸塩 (JP17)entacyloxyzin(tabl.)vermicompren(tabl.)
OxypaatPipadoxVermilasshexanedioic acid;piperazinepiperazinium adipatePiperazine adipinateV7P5P122LBNSC-74383

データベース識別子

CAS
142-88-1
PubChem CID
8905
DTXSID
DTXSID2059724
ChEMBL
CHEMBL3276110
ChEBI
CHEBI:133924
UNII
V7P5P122LB
EC Number
205-569-0

物性

構造計算による物性

極性表面積
98.7 Ų
水素結合供与体数
4
水素結合受容体数
6
回転可能結合数
5
重原子数
16
形式電荷
0
複雑度
140

実験および物理化学的性質

Solubility10 to 50 mg/mL at 63 °F (NTP, 1992)
Melting Point482 °F approximately with decomposition (NTP, 1992)
Physical DescriptionPiperazine adipate appears as odorless white crystalline powder or solid. Slightly acid taste. Melting point 256-257 °C. Dissolves slowly. pH (0.2-0.01 molar aqueous solutions) 5.45. pH (5% solution) 5 - 6. (NTP, 1992)

物理化学的性質

融点
256 · 256-257°
沸点
374.44 °C · 374.44°C (rough estimate)
比重(密度)
1.1633 · 1.1633 (rough estimate)
蒸気圧
2.8 hPa · 2.8hPa
屈折率
1.471 · 1.4710 (estimate)
貯蔵温度
-20 °C · Store at -20°C
溶解性
571.42 mg/L · 571.42mg/L in organic solvents at 20 ℃
外見
Solid
酸解離定数(Pka)
0 · 0[at 20 ℃]
色
White to Almost white
臭い (Odor)
100 %で。無臭 · 100.00%で。無臭
水溶解度
ほとんど透明

安全と法規制

安全情報は参考情報です。供給元の安全データシート(SDS)、適用法令、専門家による評価に代わるものではありません。

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 25% (1 of 4) of reports.

Danger

H314 (50%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P233, P260, P261, P264, P264+P265, P271, P272, P273, P280, P284, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P319, P321, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P363, P403, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 4 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

危険有害性情報

Regulatory Information · 3 件

Chemical: Hexanedioic acid, compound with piperazine (1:1)

REACH registered substance: Piperazine adipate (EC: 205-569-0)

Piperazine adipate: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Other Safety InformationIMAP assessments - Piperazine salts: Human health tier II assessment
Fire HazardsFlash point data for this chemical are not available; however it is probably combustible. (NTP, 1992)
Health HazardsSYMPTOMS: Symptoms of prolonged exposure to this chemical include dizziness, vomiting, blurred vision, muscular incoordination and paresthesia.
Reactive GroupSalts, Acidic
Reactivity ProfilePIPERAZINE ADIPATE gives weakly acidic aqueous solutions. Can serve as both an oxidizing agent and as a reducing agent.

化学と産業

用途と製造

General Manufacturing InformationHexanedioic acid, compd. with piperazine (1:1): INACTIVE
応用分野 · 2 件

使用Piperazine Adipate is used as an anthelmintic agent. Derivatives of piperazine are widely used in the pharmaceutical, biomedical and chemical fields. Piperazine derivatives are known to have high antiserotonin potency, antimicrobial activity, and potential anticancer activity in humans.

一般的な説明Odorless white crystalline powder or solid. Slightly acid taste. Melting point 256-257°C. Dissolves slowly. pH (0.2-0.01 molar aqueous solutions) 5.45. pH (5% solution) 5 - 6.

サプライヤー65 社

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Suzhou ARTK Medchem Co., Ltd.+86-18168183658 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Jai Radhe Sales+(91)-(79)-26431096/65255722 · [email protected]

関連反応

0 件
反応記録を作成

現在のフィルター条件では反応記録がありません。

化合物ノート

読み込み中…

このページの内容基本情報概要名称と識別子物性安全と法規制化学と産業関連反応化合物ノート
Merck
14 · 14,7465
安定性
安定。可燃性。強力な酸化剤とは相容れない。光に敏感な場合があります。
主な用途
医薬品(低分子化合物)
InChI
1S/C6H10O4.C4H10N2/c7-5(8)3-1-2-4-6(9)10;1-2-6-4-3-5-1/h1-4H2,(H,7,8)(H,9,10);5-6H,1-4H2
InChIKey
BVEGEKOBSPXUJS-UHFFFAOYSA-N
SMILES
C1CNCCN1.OC(=O)CCCCC(O)=O
LogP
-0.522 at · -0.522 at 28℃
CAS データベース
142 · 142-88-1(CAS DataBase Reference)
EPAの化学物質情報
Piperazine adipate (1:1) (142-88-1)

化学的性質

化学的特性white crystals or powder

Air and Water Reactions
Water soluble.
Hazard Classes and Categories · 2 件

Skin Corr. 1B (50%)

Eye irritation - category 2A

安全と保護具

Fire FightingFires involving this chemical can be controlled with a dry chemical, carbon dioxide, or Halon extinguisher. (NTP, 1992)
First Aid · 1 件

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. If symptoms (such as redness or irritation) develop, immediately transport the victim to a hospital.

Nonfire Spill Response · 1 件

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE) · 1 件

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

安全データ

wgk
WGK 1
tsca
TSCA listed
rtecs
MO1955000
ridadr
UN 2579 8 / PGIII
毒性
LD50 in mice, rats (g/kg): 11.4, 7.9 orally (Cross)
hs_code
2933599550
ストレージクラス
11 - Combustible Solids
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