Boc-L-methionine (HCID 89857)

名称と識別子

優先名称: Boc-L-methionine
IUPAC: (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-methylsulfanylbutanoic acid
現地名: N-(tert-ブトキシカルボニル)-L-メチオニン
英語名: BOC-L-Methionine
分子式: C10H19NO4S
分子量: 249.33

名称と別名

Boc-L-methionine2488-15-5RefChem:330045Boc-Met-OHN-Boc-L-methionineBoc-L-Met-OH(TERT-BUTOXYCARBONYL)-L-METHIONINEMFCD00065586L-Methionine, N-[(1,1-dimethylethoxy)carbonyl]-N-(tert-Butoxycarbonyl)-L-methionineN-tert-butoxycarbonyl-L-methionine(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-methylsulfanylbutanoic acid

名称をさらに表示

N-(tert-ブトキシカルボニル)-L-メチオニンN-[(1,1-ジメチルエトキシ)カルボニル]-L-メチオニン(S)-2-[(tert-ブチルオキシカルボニル)アミノ]-4-(メチルチオ)酪酸N-(tert-ブチルオキシカルボニル)-L-メチオニンN-(tert-ブトキシカルボニル)メチオニン(S)-4-(メチルチオ)-2-[(tert-ブトキシカルボニル)アミノ]ブタン酸BOC-L-メチオニンN-Boc-L-メチオニンN‐BOC‐L‐メチオニン(2S)-2-{[(tert-ブトキシ)カルボニル]アミノ}-4-(メチルスルファニル)ブタン酸BOC-MET(S)-2-((tert-butoxycarbonyl)aMino)-4-(Methylthio)butanoic acidBoc-Met-OBoc-D-Met-OH

(2S)-2-{[(tert-butoxy)carbonyl]amino}-4-(methylsulfanyl)butanoic acid(2S)-2-[(tert-butoxy)carbonylamino]-4-methylthiobutanoic acidBoc-methionineboc-l-metN-Boc methionineMethionine, N-[(1,1-dimethylethoxy)carbonyl]-(S)-Boc-methionineN-Boc-L-Met-OH

データベース識別子

CAS: 2488-15-5
PubChem CID: 89857
ChEMBL: CHEMBL117467
UNII: 67R3EKW5EK
EC Number: 219-639-3
Nikkaji: J191.976H

物性

構造計算による物性

XLogP: 1.6
極性表面積: 101 Å²
水素結合供与体数: 2
水素結合受容体数: 5
回転可能結合数: 7
重原子数: 16
形式電荷: 0
複雑度: 250

物理化学的性質

融点: 47 · 47-50 °C(lit.)
比旋光度: -23 · -23 º (c=1.3, methanol)
沸点: 415.5 · 415.5±40.0 °C(Predicted)
比重(密度): 1.16 · 1.160±0.06 g/cm3(Predicted)
屈折率: -22 ° · -22 ° (C=1.3, AcOH)
貯蔵温度: Keep in dark place,Sealed in dry,Room Temperature
溶解性: almost transparency in Methanol
外見: 粉
酸解離定数(Pka): 3.83 · 3.83±0.10(Predicted)
色: ホワイトからオフホワイト
BRN: 1727869 · 1727869
主な用途: ペプチド合成
InChI: 1S/C10H19NO4S/c1-10(2,3)15-9(14)11-7(8(12)13)5-6-16-4/h7H,5-6H2,1-4H3,(H,11,14)(H,12,13)/t7-/m0/s1
InChIKey: IMUSLIHRIYOHEV-ZETCQYMHSA-N
SMILES: CSCC[C@H](NC(=O)OC(C)(C)C)C(O)=O
CAS データベース: 2488 · 2488-15-5(CAS DataBase Reference)

化学的性質

化学的特性white to off-white microcrystalline powder

安全と法規制

GHS分類

GHS Classification · 5 件

This chemical does not meet GHS hazard criteria for 40% (2 of 5) of reports.

Danger

H315 (20%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 5 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Hazard Classes and CategoriesSkin Irrit. 2 (20%)

安全データ

F: 9-23
wgk: 3
hs_code: 2930 90 98
risk_code: 20/21/22-36/37/38
hazard_code: Xn
safety_code: 24/25-36-26
ストレージクラス: 11 - Combustible Solids

化学と産業

応用分野 · 2 件

用途ペプチドを合成する際の原料として用いられる。

使用N-Boc-L-methionine is an N-Boc-protected form of L-Methionine (M260440). L-Methionine is an essential amino acid that is obtained from our diet. L-Methionine can be found in grain legumes (such as lentils), and poultry. L-Methionine’s main function is to act as the primary “Start” sequence on mRNA so that the ribosomes can start translating the mRNA into proteins.