3-メトキシフェノール

解説メトキシフェノールとは、の水素原子1つがメトキシ基に置換した有機化合物です。 フェノール類の1種です。ヒドロキシアニソールとも呼ばれています。パラ体・オルト体・メタ体の異性体が存在し、p-メトキシフェノール、o-メトキシフェノール、m-メトキシフェノールの3種類です。 いずれの異性体も、分子式はC7H8O2で、分子量は124.14です。

使用A phenol derivative, 3-Methoxyphenol can be used as catalysts and as building blocks in synthesis of organic compounds such as antioxidants.

一般的な説明3-Methoxyphenol is a phenolic aroma compound typically present in food and beverage products.

使用用途m-メトキシフェノールは、抗酸化剤などの有機化合物を合成する際に、触媒やビルディングブロックとして使用されています。さらに、ガスクロマトグラフィー分析における標準物質としての用途もあります。

製造方法synthesis of 3-methoxyphenol: The 1 mole of resorcinol is treated rapidly with stirring, in a three-necked flask provided with a reflux condenser, stirrer, internal thermometer, and dropping funnel, with 1.25 mole of 10% sodium hydroxide. With vigorous stirring, 1 mole of dimethyl sulfate is added in such a way that the temperature remains below 40° C (water cooling). To complete the reaction and to destroy unchanged dimethyl sulfate, the mixture is then heated for 30 min on a boiling water bath. After cooling, the organic layer is separated off and the aqueous solution is extracted several times with ether. The combined organic phases are washed with dilute sodium carbonate and then with water, dried with calcium chloride, and fractionated. Unchanged resorcinol can be recovered by acidifying the aqueous reaction solution and the wash water and extracting them with ether. The yield of 3-methoxyphenol is 50%, b.p. 113-115 °C/5 mm; b.p. 144°C/25mm; n20/D 1.552; d=1.131 g/mL at 25 °C. Organicum. Practical Handbook of Organic Chemistry, by Heinz Becker, Werner Berger and Günter Domschke, Addison-Wesley Pub. Co, 206-207, (1973)