アクリル酸カルボキシエチル

2-Carboxyethyl acrylate

HCID 90558

基本情報

CAS
24615-84-7
標準SMILES
C=CC(=O)OCCC(=O)O
InChIKey
CYUZOYPRAQASLN-UHFFFAOYSA-N
分子式
C6H8O4
平均分子量
144.12 g/mol
単同位体質量
144.04225873

名称と識別子

優先名称
2-Carboxyethyl acrylate
IUPAC
3-prop-2-enoyloxypropanoic acid
現地名
アクリル酸カルボキシエチル
英語名
2-Carboxyethyl acrylate
分子式
C6H8O4
分子量
144.13

名称と別名

2-Carboxyethyl acrylate24615-84-72-Propenoic acid, 2-carboxyethyl ester3-Acryloyloxypropionic acidbeta-Carboxyethyl acrylate2-Carboxyethyl 2-propenoatebeta-(Acryloyloxy)propionic acidDTXSID2027834KM1E1216WRARONIX M 566C 800 (ACRYLATE)DTXCID807834
名称をさらに表示
3-アクリロイルオキシプロピオン酸アクリル酸カルボキシエチルアクリル酸2-カルボキシエチル3-(プロパ-2-エノイルオキシ)プロパン酸3-[(エテニル)カルボニルオキシ]プロピオン酸2-カルボキシエチルアクリラート3-(アクリロイルオキシ)プロパン酸アクリル酸β-カルボキシエチル3-(アクリロイルオキシ)プロピオン酸B-CEAβ-Carboxyethyl acrylateβ-Carboxyethyl AcrylateL-61045sipomerb-ceaSolvay β-CEAEinecs 246-359-9RARECHEM AL BO 0311
EBECRYL BETA-CEARefChem:4681802-carboxyethyl ester 2-propenoic acid246-359-93-prop-2-enoyloxypropanoic acid3-(acryloyloxy)propanoic acid2-carboxyethylacrylateHydracrylic acid acrylate

データベース識別子

CAS
24615-84-7
PubChem CID
90558
DTXSID
DTXSID2027834
ChEMBL
CHEMBL3185107
UNII
KM1E1216WR
EC Number
246-359-9
Nikkaji
J52.386K

物性

構造計算による物性

XLogP
0.2
極性表面積
63.6 Ų
水素結合供与体数
1
水素結合受容体数
4
回転可能結合数
5
重原子数
10

実験および物理化学的性質

Physical DescriptionLiquid

物理化学的性質

沸点
103 °C/19 · 103 °C/19 mmHg (lit.)
比重(密度)
1.214 g/mL · 1.214 g/mL at 25 °C (lit.)
屈折率
20 · n20/D 1.457(lit.)
闪点
230 °F · >230 °F
貯蔵温度
2 · 2-8°C
溶解性
2 O: · H2O: 可溶

化学的性質

化学的特性Colorless to light yellow viscid liquid

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 7.1% (55 of 775) of reports.

Danger

H302 (71.2%): Harmful if swallowed [Warning Acute toxicity, oral];H312 (57.7%): Harmful in contact with skin [Warning Acute toxicity, dermal];H314 (77.8%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation];H315 (14.8%): Causes skin irritation [Warning Skin corrosion/irritation];H318 (73%): Causes serious eye damage [Danger Serious eye damage/eye irritation];H319 (14.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P260, P264, P264+P265, P270, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P321, P330, P332+P317, P337+P317, P362+P364, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 775 reports by companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 55 of 775 reports by companies.;There are 13 notifications provided by 720 of 775 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

危険有害性情報

Regulatory Information · 3 件

Chemical: 2-Propenoic acid, 2-carboxyethyl ester

2-Propenoic acid, 2-carboxyethyl ester is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 2-Propenoic acid, 2-carboxyethyl ester are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

2-Propenoic acid, 2-carboxyethyl ester: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesAcute Tox. 4 (71.2%);Acute Tox. 4 (57.7%);Skin Corr. 1B (77.8%);Skin Irrit. 2 (14.8%);Eye Dam. 1 (73%);Eye Irrit. 2 (14.8%)

法規制情報

Regulatory Information · 3 件

Chemical: 2-Propenoic acid, 2-carboxyethyl ester

2-Propenoic acid, 2-carboxyethyl ester is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 2-Propenoic acid, 2-carboxyethyl ester are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

2-Propenoic acid, 2-carboxyethyl ester: Does not have an individual approval but may be used under an appropriate group standard

安全データ

wgk
3
tsca
TSCA listed
rtecs
UD3325250
ridadr
UN 3265 8/PG 2
hs_code
29161290
risk_code
34-36/37/38

化学と産業

用途と製造

U.S. Production2023: 10,000,000 - <50,000,000 lb;2022: 10,000,000 - <50,000,000 lb;2021: 10,000,000 - <50,000,000 lb;2020: 10,000,000 - <50,000,000 lb
Consumer UsesMonomers
Industry UsesMonomers;Intermediate
General Manufacturing Information · 2 件

Paint and Coating Manufacturing;All Other Chemical Product and Preparation Manufacturing;Printing and Related Support Activities;Adhesive Manufacturing;Miscellaneous Manufacturing;All Other Basic Organic Chemical Manufacturing

2-Propenoic acid, 2-carboxyethyl ester: ACTIVE

応用分野

使用2-Carboxyethyl Acrylate is used in the preparation of DNase enzyme derivatives that act as potent preventative material of bacterial adhesion and biofilm formation in biomaterials.

調製方法 · 1 件

製造方法Synthesis of 1-ethoxyethyl acrylate (EEA) and protected 2-carboxyethyl acrylate (proCEA)EEA and proCEA were synthesized following a previously published procedure and distilled prior to use. For the synthesis of proCEA (Figure 1), phosphoric acid (109 mg, 1.11 mmol) was weighed into a dry round bottom flask in a glovebox and then taken outside the glovebox, taking care that the phosphoric acid stayed dry. 2-Carboxyethyl acrylate (80 g, 555 mmol) and ethyl vinyl ether (48 g, 666 mmol) were added and the reaction was stirred for two days at room temperature. Hydrotalcite (Mg6Al2(OH)16CO3·4H2O, ~1 g) was added, stirred for one hour and filtered off. Excess ethyl vinyl ether was removed under reduced pressure and the product was distilled under reduced pressure (80 °C, 1.3 mbar).Figure 1 Synthesis of proCEA

サプライヤー100 社

国药集团化学试剂有限公司86-21-63210123 · [email protected]
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]
湖南韵邦生物科技股份有限公司85561037 15386497078 · [email protected]
湖北万得化工有限公司15377098680 15377098680 · [email protected]

補足説明

定義本品は、次の化学式で表される有機化合物である。

関連反応

5 件

化合物ノート

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