Potassium Sodium Tartrate (HCID 9357)

概要

Potassium sodium L-tartrate is the organic sodium and potassium salt of L-tartaric acid (mol ratio 1:1:1). It has a role as a laxative. It is a potassium salt and an organic sodium salt. It contains a L-tartrate(2-).

名称と識別子

優先名称: Potassium Sodium Tartrate
IUPAC: potassium;sodium;(2R,3R)-2,3-dihydroxybutanedioate

名称と別名

Rochelle saltSeignette salt304-59-6SODIUM POTASSIUM TARTRATEMonopotassium monosodium tartrateSodium potassium L-tartratePotassium sodium L(+)-tartratePotassium sodium tartrate anhydrousP49F8NV7ESTartaric acid, monopotassium monosodium salt2,3-Dihydroxybutanedioic acid, monopotassium monosodium saltButanedioic acid, 2,3-dihydroxy-, monopotassium monosodium salt

名称をさらに表示

CHEBI:63019DTXSID90889341INS NO.337Potassium sodium dextro-tartrateINS-337E-337Co eff pdrRefChem:570851

データベース識別子

CAS: 147-79-5、15490-42-3、304-59-6、6381-59-5
PubChem CID: 9357
DTXSID: DTXSID60932999
ChEBI: CHEBI:63019
UNII: P49F8NV7ES
EC Number: 205-698-2、206-156-8、613-385-0
Nikkaji: J2.573I

物性

構造計算による物性

極性表面積: 121 Å²
水素結合供与体数: 2
水素結合受容体数: 6
回転可能結合数: 1
重原子数: 12
形式電荷: 0
複雑度: 123

実験および物理化学的性質

Chemical ClassesMetals -> Organic Acids, Metal Salts

CosmeticsBuffering

pHBetween 6,5 and 8,5 (1 % aqueous solution)

TasteCool, saline taste

Food AdditivesEMULSIFIER OR EMULSIFIER SALT, PH CONTROL AGENT, SEQUESTRANT -> FDA Substance added to food

Density · 2 件

Density: 1.77 (Air=1)

1.77 @25 °C

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 99.6% (234 of 235) of all reports.

Not Classified

Aggregated GHS information provided per 235 reports by companies from 3 notifications to the ECHA C&L Inventory.

This chemical does not meet GHS hazard criteria for 100% (42 of 42) of all reports.

Not Classified

Aggregated GHS information provided per 42 reports by companies from 2 notifications to the ECHA C&L Inventory.

危険有害性情報

Regulatory Information · 6 件

Chemical: Butanedioic acid, 2,3-dihydroxy- [R-(R*,R*)]-, monopotassium monosodium salt

Regulation (EC) No 1333/2008 (amended)

Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, potassium sodium salt (1:1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, potassium sodium salt (1:1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 29-09-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/14183

Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, monopotassium monosodiumsalt: Does not have an individual approval but may be used under an appropriate group standard

Potassium sodium tartrate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationEvaluation - Chemicals that are unlikely to require further regulation to manage risks to environment

Hazards SummaryGenerally regarded as safe (GRAS) for use in foods; Saline cathartics are contraindicated in a patient with congestive heart failure on a low sodium diet; [HSDB]

FDA Requirements · 2 件

Substance added directly to human food affirmed as generally recognized as safe (GRAS) when meeting specified requirements.

Sodium potassium tartrate used as a general purpose food additive in animal drugs, feeds, and related products is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

Hazard Classes and Categories · 3 件

Not Classified

安全と保護具

Cleanup MethodsPOTASSIUM SODIUM TARTRATE WAS ADSORBED WITH NICKEL PEROXIDE POWDER (SURFACE AREA 200 SQ M/G) FROM SOLUTIONS.

Protective Action Criteria (PAC) · 3 件

90 [mg/m3]

99 [mg/m3]

590 [mg/m3]

毒性情報

Non-Human Toxicity Excerpts · 2 件

A SINGLE IV DOSE OF SODIUM POTASSIUM TARTRATE, 400 MG/KG SELECTIVELY INJURED EPITHELIUM OF THE CONVOLUTED TUBULE IN MICE.

MICE WERE TREATED WITH 400 MG/KG SC. NUMBER OF PANETH CELLS COUNTED IN INTESTINAL GLANDS DID NOT CHANGE SIGNIFICANTLY, BUT GRANULAR INDICES DECR DISTINCTLY ON 1ST DAY AFTER TREATMENT, THEN NORMALIZED BY 5 DAYS.

法規制情報

FDA Requirements · 2 件

Substance added directly to human food affirmed as generally recognized as safe (GRAS) when meeting specified requirements.

Sodium potassium tartrate used as a general purpose food additive in animal drugs, feeds, and related products is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

化学と産業

用途と製造

Uses · 6 件

Used as sequestrant and general purpose food additive; Used in mirror production, Fehling's solution, crystal-controlled oscillators, and as saline cathartic; [HSDB]

SEQUESTRANT & GENERAL PURPOSE FOOD ADDITIVE.

FOOD CHEMICAL: EMULSIFIER IN CHEESE, BUFFER IN CONFECTIONS, IN FRUIT JELLY, PRESERVES & JAMS; AS SALINE CATHARTIC; IN MFR OF MIRRORS; CONSTITUENT OF FEHLING'S SOLUTION; IN CRYSTAL-CONTROLLED ELECTRONIC OSCILLATORS.

Emulsifier in cheese

Baking powders; silvering mirrors

MEDICATION

U.S. Production · 3 件

2023: 50,000 - <75,000 lb

(1972) PROBABLY GREATER THAN 4.54X10+5 GRAMS

(1975) PROBABLY GREATER THAN 4.54X10+5 GRAMS

Consumer UsesProcessing aids not otherwise specified

Industry UsesPlating agent

Methods of Manufacturing · 2 件

REACTION OF POTASSIUM ACID TARTRATE, WATER, & SODIUM CARBONATE

BY REACTING DOUBLE MOLAR PORTION OF POTASSIUM BITARTRATE WITH HOT SOLN OF SODIUM CARBONATE.