エチレンジアミン二塩酸塩
エチレンジアミン二塩酸塩 · エチレンジアミン·二塩酸塩 · エチレンジアミン·2塩酸塩 · エチレンジアミン·2塩酸 · 1,2-エタンジアミン·二塩酸塩 · ETHYLENE DIAMINE DIHYDROCHLORIDE (100 ΜG/ML IN MEOH) · エチレンジアンモニウムジクロリド · エチレンジアミン 二塩酸塩
識別子と物理属性
| CAS No. | 333-18-6 |
|---|---|
| 分子式 | C2H10Cl2N2 |
| 平均分子量 | 133.02 g/mol |
| 単同位体質量 | 132.0221037 g/mol |
| SMILES | Cl.Cl.NCCN |
| InChIKey | OHHBFEVZJLBKEH-UHFFFAOYSA-N |
| PubChem CID | 9521 |
| ChEBI | CHEBI:53626 |
| EC No. | 206-369-6 |
| DTXSID | DTXSID5043920 |
| 現地名 | エチレンジアミン二塩酸塩 |
化学・物理的性質
| 極性表面積 | 52 |
|---|---|
| 水素結合供与体数 | 4 |
| 水素結合受容体数 | 2 |
| 回転可能結合数 | 1 |
| 重原子数 | 6 |
| 形式電荷 | 0 |
| 複雑度 | 6 |
| Physical Description | White crystalline solidHygroscopic[Sigma-Aldrich MSDS] |
| 融点 | >300 °C(lit.) |
| 密度 | 1.46 g/cm3 |
| 貯蔵条件 | Store below +30°C. |
| 溶解度 | 水：可溶100mg/mL 無色透明～微微黄色300g/L(20℃) |
| 外観・状態 | 結晶性粉末 |
| 色 | ホワイトからオフホワイト |
| pH | 5 (100g/l, H2O, 20℃) |
| BRN | 3665235 |
| 安定性 | 安定。強力な酸化剤とは相容れない。 |
| InChI | InChI=1S/C2H8N2.2ClH/c3-1-2-4/h1-4H22*1H |
| InChIKey | OHHBFEVZJLBKEH-UHFFFAOYSA-N |
| SMILES | C(N)CN.Cl.Cl |
| CAS データベース | 333-18-6(CAS DataBase Reference) |
| EPAの化学物質情報 | Ethylenediamine dihydrochloride (333-18-6) |
化学的特性
white crystalline powder
安全性と法規制
| GHS 分類 | DangerH302 (94.4%): Harmful if swallowed [Warning Acute toxicity, oral]H315 (93%): Causes skin irritation [Warning Skin corrosion/irritation]H317 (93%): May cause an allergic skin reaction [Warning Sensitization, Skin]H319 (93%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H334 (88.7%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]H335 (88.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P233, P260, P261, P264, P264+P265, P270, P271, P272, P280, P284, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 71 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| 規制情報 | Chemical: 1,2-Ethanediamine, dihydrochlorideEthylenediammonium dichloride: Does not have an individual approval but may be used under an appropriate group standard |
| 有害性の概要 | Causes allergic dermatitis in 48-hr constant dermal studies of humans[RTECS] A skin and strong eye irritantMay cause skin and respiratory sensitizationHarmful by ingestionReproductive and developmental toxicity observed in experimental animals[Sigma-Aldrich MSDS] See Ethylenediamine. |
| Hazard Classes and Categories | Acute Tox. 4 (94.4%)Skin Irrit. 2 (93%)Skin Sens. 1 (93%)Eye Irrit. 2A (93%)Resp. Sens. 1 (88.7%)STOT SE 3 (88.7%) |
| Protective Action Criteria (PAC) | 2.7 [mg/m3]29 [mg/m3]180 [mg/m3] |
| 有害作用 | Skin Sensitizer - An agent that can induce an allergic reaction in the skin.Asthma - Reversible bronchoconstriction (narrowing of bronchioles) initiated by the inhalation of irritating or allergenic agents. |
| 水環境危害等級（WGK） | 2 |
| TSCA 収載状態 | TSCA listed |
| RTECS 番号 | KV3850000 |
| 毒性 | LD50 orally in Rabbit: 3250 mg/kg LD50 dermal Rabbit > 2000 mg/kg |
| 税関コード | 29212100 |
| 危険文句（R） | 22-36/37/38-42/43 |
| 化審法 | (2)-150 |
| 危険表示 | Xn |
| 安全措置（S） | 22-26-36/37-45 |
| 危険等級 | Acute Tox. 4 OralEye Irrit. 2Resp. Sens. 1Skin Irrit. 2Skin Sens. 1STOT SE 3 |
| 貯蔵分類 | 11 - Combustible Solids |
用途
用途
金属分析及びキレート剤。
使用
Ethylenediamine dihydrochloride is used as stabilizer in steroid creams and rubber latex; inhibitor in antifreeze solutions and cooling fluids; in floor-polish remover; in nystatin cream and aminophylline; epoxy-curing agent; accelerator in color development baths in photography; in veterinary preparations; in electroplating and electrophoretic gels, dyes, fungicides, insecticides, synthetic waxes, textile lubricants, and eye and nose drops; solvent for casein, albumin, shellac.
製法・合成法
純化方法
Crystallise the salt from H2O or H2O/EtOH. Wash the crystals with EtOH and dry them in vacuo. It sublimes on heating. [Beilstein 4 IV 1168.]