N-(2-hydroxyethyl)lactamide (HCID 95457)

概要

N-Lactoyl ethanolamine is a N-acylethanolamine.

名称と識別子

優先名称: N-(2-hydroxyethyl)lactamide
IUPAC: 2-hydroxy-N-(2-hydroxyethyl)propanamide
現地名: N-(2-ヒドロキシエチル)ラクトアミド
英語名: N-(2-Hydroxyethyl)lactamide
分子式: C5H11NO3
分子量: 133.15

名称と別名

N-(2-Hydroxyethyl)lactamide2-LactamidoethanolRefChem:4733581-hydroxyethane-1-(2'-hydroxyethyl)carbonamide5422-34-42-Hydroxy-N-(2-hydroxyethyl)propanamideLactamide MEAPropanamide, 2-hydroxy-N-(2-hydroxyethyl)-n-lactoyl ethanolamineLactic acid monoethanolamideLactamide, N-(2-hydroxyethyl)-N-2-Hydroxyethyllactamide

名称をさらに表示

N-(2-ヒドロキシエチル)ラクトアミド2-ヒドロキシ-N-(2-ヒドロキシエチル)プロパンアミドN-β-ヒドロキシエチル-β-ヒドロキシプロピオン酸アミドN-(2-ヒドロキシエチル)-2-ヒドロキシプロパンアミドN-(2-ヒドロキシエチル)-2-ヒドロキシプロピオンアミドラクタミドMEAMFCD0003Naetex-LAMlactamidemeaMackamide LMESchercomid LMEParapel LAM-100Upamide LACAMEA

MFCD00037805N-HydroxyaethyllactamidCCRIS 3086Lipamide LMEAIncromectant LMEAN-beta-HydroxyethyllactamideNSC 11062Monoethanolamine lactic acid amide

データベース識別子

CAS: 5422-34-4
PubChem CID: 95457
DTXSID: DTXSID20863533
ChEBI: CHEBI:173359
UNII: 900T44YNC7
EC Number: 226-546-1
Nikkaji: J60.793B

物性

構造計算による物性

XLogP: -1.4
極性表面積: 69.6 Å²
水素結合供与体数: 3
水素結合受容体数: 3
回転可能結合数: 3
重原子数: 9
形式電荷: 0
複雑度: 94.2

実験および物理化学的性質

Cosmetics · 2 件

Cosmetic ingredients (Lactamide MEA) -> CIR (Cosmetic Ingredient Review)

Skin conditioning; Humectant; Antistatic; Hair conditioning

FragrancesFragrance Ingredient (N-Lactoyl ethanolamine) -> IFRA transparency List

Food AdditivesFLAVORING AGENT OR ADJUVANT -> FDA Substance added to food

Density1.182-1.186

Solubility · 2 件

Very soluble in water; insoluble in pentane and diethyl ether

Slightly soluble (in ethanol)

Boiling Point · 2 件

380.00 °C. @ 760.00 mm Hg

372-380 °C

物理化学的性質

沸点: 380.3 · 380.3±27.0 °C(Predicted)
比重(密度): 1 · 1,2 g/cm3
屈折率: 1.482 to · 1.4820 to 1.4870
FEMA: 4256 · 4256 | N-LACTOYL ETHANOLAMINE
貯蔵温度: Sealed in dry,Room Temperature
外見: clear liquid
酸解離定数(Pka): 13.34 · 13.34±0.20(Predicted)
色: Light yellow to Yellow to Orange
臭い (Odor): 調理した
JECFA Number: 1774 · 1774
主な用途: フレーバーそして香料
化粧品成分の機能: 保湿剤帯電防止ヘアコンディショニングスキンコンディショニング
InChI: InChI=1S/C5H11NO3/c1-4(8)5(9)6-2-3-7/h4,7-8H,2-3H2,1H3,(H,6,9)
InChIKey: RZCHTMXTKQHYDT-UHFFFAOYSA-N
SMILES: C(NCCO)(=O)C(O)C
LogP: -2.31 · -2.31
CAS データベース: 5422 · 5422-34-4(CAS DataBase Reference)
EPAの化学物質情報: 2 · Propanamide, 2-hydroxy-N-(2-hydroxyethyl)- (5422-34-4)

化学的性質

化学的特性Viscous, brownish liquid; cooked brown roasted aroma

安全と法規制

GHS分類

GHS Classification · 3 件

This chemical does not meet GHS hazard criteria for 97.3% (1363 of 1401) of all reports.

Not Classified

Aggregated GHS information provided per 1401 reports by companies from 4 notifications to the ECHA C&L Inventory.

危険有害性情報

Regulatory Information · 5 件

Chemical: Propanamide, 2-hydroxy-N-(2-hydroxyethyl)-

Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)

Propanamide, 2-hydroxy-N-(2-hydroxyethyl)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Propanamide, 2-hydroxy-N-(2-hydroxyethyl)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 18-07-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/21492

Propanamide, 2-hydroxy-N-(2-hydroxyethyl)-: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesNot Classified

毒性情報

Toxicity Summary · 2 件

The CIR Expert Panel concluded that the ethanolamides listed subsequently are safe in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating. The Expert Panel cautioned that these ingredients should not be used in cosmetic products in which N-nitroso compounds may be formed...Lactamide MEA...

Safe for use in cosmetics, with qualifications

安全データ

wgk: WGK 3
tsca: TSCA listed
rtecs: OD2400000
hs_code: 2922.39.5000
risk_code: 36/37/38
化審法: (2)-1378
消防法: 危-4-4-III
safety_code: 26-36/37/39
ストレージクラス: 10 - Combustible liquids

化学と産業

薬理情報

Cellular LocationsCytoplasm

用途と製造

UsesCIR ingredient: Lactamide MEA

U.S. Production2023: 137,300 lb

Consumer UsesHumectant

Industry UsesProcessing aids not otherwise specified

Household ProductsInformation on 1 consumer products that contain Lactamide Mea in the following categories is provided:

Use Classification · 4 件

Fragrance Ingredients

Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes

Flavoring Agents -> JECFA Flavorings Index

Cosmetics -> Skin conditioning; Humectant; Antistatic; Hair conditioning

応用分野

使用lactamide MEA is a surfactant that can also act as a thickener, foam booster, and stabilizer.

サプライヤー46 社

北京华美互利生物化工010-56205725 · [email protected]

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

南京世洲生物科技有限公司025-85560043 15850508050 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]

補足説明

定義本品は、乳酸(*)のモノエタノールアミドであり、次の化学式で表される。参照表示名称：乳酸

N-(2-ヒドロキシエチル)ラクトアミド

基本情報

概要