基本情報
- CAS
204519-65-3- 標準SMILES
CO/N=C1\CN(c2nc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1CN.CS(=O)(=O)O- InChIKey
JIYMVSQRGZEYAX-CWUUNJJBSA-N- 分子式
- C19H24FN5O7S
- 平均分子量
- 485.5 g/mol
- 単同位体質量
- 485.13804746
概要
Gemifloxacin mesylate is the mesylate salt of gemifloxacin. It has a role as an antimicrobial agent and a topoisomerase IV inhibitor. It contains a gemifloxacin.
名称と識別子
- 優先名称
- Gemifloxacin Mesylate
- IUPAC
- 7-[(4Z)-3-(aminomethyl)-4-methoxyiminopyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;methanesulfonic acid
- 英語名
- GemifloxacinMesylate
- 分子式
- C19H24FN5O7S
- 分子量
- 0
名称と別名
Gemifloxacin mesylate210353-53-0FactiveGemifloxacin mesilateGemifloxacin methanesulfonateLB 20304aDTXSID7045948LB-20304aSB-265805-SX4S9F8RL01DTXCID5025948CHEBI:53749
名称をさらに表示
gemifloxacin mesylate salt7-[(4~{Z})-3-(aminomethyl)-4-methoxyiminopyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
1,8-Naphthyridine-3-carboxylic acid, 7-[(4Z)-3-(aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, monomethanesulfonate1,8-Naphthyridine-3-carboxylic acid, 7-((4Z)-3-(aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, monomethanesulfonate7-((4Z)-3-(Aminomethyl)-4-methoxyiminopyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-(1,8)naphthyridine-3-carboxylic acid monomethanesulfonateRefChem:56636988-321-0Gemifioxacin Mesylate(Z)-Gemifloxacin Mesilate204519-65-3
データベース識別子
- CAS
204519-65-3、210353-53-0- PubChem CID
- 9588170
- DTXSID
DTXSID7045948- ChEMBL
CHEMBL1200621
物性
構造計算による物性
- 極性表面積
- 184 Ų
- 水素結合供与体数
- 3
- 水素結合受容体数
- 13
- 回転可能結合数
- 5
- 重原子数
- 33
- 形式電荷
- 0
- 複雑度
- 817
実験および物理化学的性質
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
安全と法規制
安全情報は参考情報です。供給元の安全データシート（SDS）、適用法令、専門家による評価に代わるものではありません。
GHS分類
GHS Classification
Warning
H317 (50%): May cause an allergic skin reaction [Warning Sensitization, Skin]
P203, P260, P261, P272, P280, P302+P352, P318, P319, P321, P333+P317, P362+P364, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
危険有害性情報
Hazard Classes and CategoriesSkin Sens. 1 (50%)
毒性情報
Drug Induced Liver Injury
Drug Induced Liver Injury Rank (DILIrank 2.0)
Gemifloxacin mesylate
vLess-DILI-concern
3
Warnings & precautions
DOI:10.1016/j.drudis.2016.02.015
化学と産業
薬理情報
MeSH Pharmacological Classification
Substances that inhibit the growth or reproduction of BACTERIA.
Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II.
応用分野
使用Antibacterial.
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