CAS 51209-75-7 S-Nitrosocysteine (HCID 9793848)

基本情報

CAS: 51209-75-7
標準SMILES: N[C@@H](CSN=O)C(=O)O
InChIKey: XOWVFANEOZMPKG-REOHCLBHSA-N
分子式: C3H6N2O3S
平均分子量: 150.16 g/mol

概要

S-nitroso-L-cysteine is an L-cysteine derivative in which the sulfur atom carries a nitroso substituent. A cell-permeable low-molecular-weight nitrosothiol and nitric oxide donor. It has a role as a vasodilator agent, a hematologic agent and a platelet aggregation inhibitor. It is a nitrosothio compound and a L-cysteine derivative.

名称と識別子

優先名称: S-Nitrosocysteine
IUPAC: (2R)-2-amino-3-nitrososulfanylpropanoic acid

名称と別名

S-NitrosocysteineNitrosocysteineS-Nitroso-L-cysteine51209-75-7L-S-nitrosocysteineCHEBI:138935926P2322P4L-SNC compoundSNC compoundDTXSID40965482RefChem:180703DTXCID801393151

名称をさらに表示

s-nitroso-cysteine(2R)-2-amino-3-nitrososulfanylpropanoic acidS-Nitroso-L-CysteinNO-cysteineCysNONO-L-cysteineL-CysSNOEpitope ID:735795

データベース識別子

CAS: 51209-75-7
PubChem CID: 9793848
ChEMBL: CHEMBL300676
ChEBI: CHEBI:138935
UNII: 926P2322P4
Nikkaji: J293.778F

物性

構造計算による物性

XLogP: -3.4
極性表面積: 118 Å²
水素結合供与体数: 2
水素結合受容体数: 6
回転可能結合数: 3
重原子数: 9
形式電荷: 0
複雑度: 118

化学と産業

薬理情報

MeSH Pharmacological Classification · 3 件

Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.

Drugs used to cause dilation of the blood vessels.

A diverse group of agents, with unique chemical structures and biochemical requirements, which generate NITRIC OXIDE. These compounds have been used in the treatment of cardiovascular diseases and the management of acute myocardial infarction, acute and chronic congestive heart failure, and surgical control of blood pressure. (Adv Pharmacol 1995;34:361-81)