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Ferrous glycinate

HCID 9837124
ノート反応
基本情報概要名称と識別子物性安全と法規制化学と産業関連反応化合物ノート
部分構造検索類似構造を探す

基本情報

CAS
20150-34-9
標準SMILES
NCC(=O)[O-].NCC(=O)[O-].[Fe+2]
InChIKey
GIPOFCXYHMWROH-UHFFFAOYSA-L
分子式
C4H8FeN2O4
平均分子量
203.96 g/mol
単同位体質量
203.983342

概要

Ferrous bisglycinate is a chelate that is used as a source of dietary iron. Forming a ring structure when reacting with glycine, ferrous bisglycinate acts as both a chelate and a nutritionally functional. It is found in foods for food enrichment or in supplements for the treatment of iron deficiency or iron deficiency anemia.

名称と識別子

優先名称
Ferrous glycinate
IUPAC
bis(2-aminoacetate);iron(2+)
英語名
Ferrous Bisglycinate
分子式
C4H8FeN2O4
分子量
203.96

名称と別名

Ferrous bisglycinate20150-34-9FERROUS GLYCINATEIron Bis-glycinateBisglycino-iron(II) chelateIron bis-glycinate chelateDTXSID30173978SFW1D987QVRefChem:140305DTXCID2096469Bis(glycinato-kappaN,kappaO)ironiron trisglycinate
名称をさらに表示
FERROCHELFerric GlycineFerrous GglycinateFerrous Bis-glycineIron(II) bisglycinateFERROUS(II) GLYCINATEFerric Glycine CoMplexBisglycine iron(II) salt
2-aminoacetate;iron(2+)MFCD07780318FERROUSBISGLYCINATEC4H8FeN2O4Iron(II) glycinateferrous;2-aminoacetateBis(2-aminoacetoxy)ironIron(2+) bis(aminoacetate)

データベース識別子

CAS
20150-34-9
PubChem CID
9837124
DTXSID
DTXSID30173978
ChEMBL
CHEMBL4297753
UNII
SFW1D987QV
EC Number

物性

構造計算による物性

極性表面積
132 Ų
水素結合供与体数
2
水素結合受容体数
6
回転可能結合数
0
重原子数
11
形式電荷
0
複雑度
37.4

物理化学的性質

融点
162 °C · >162°C (dec.)
沸点
150 ℃ · 150℃ at 101kPa
比重(密度)
1.898 at · 1.898 at 20℃
蒸気圧
0 · 0-0Pa at 20-25℃
貯蔵温度
Keep in dark place,Inert atmosphere,Room temperature
溶解性
水性酸(わずかに)
外見
個体
色
ペールブラウンからブラウン
水溶解度
35.71 mg/mL · Water: 35.71 mg/mL (176.83 mM)
安定性
吸湿性
化粧品成分の機能
スキンコンディショニング抗酸化物質
InChI
InChI=1S/2C2H4NO2.Fe/c2*3-1-2(4)5;/h2*3H,1H2,(H,4,5);/q2*-1;+4/p-2
InChIKey
MECJLZIFMOMXPW-UHFFFAOYSA-L
SMILES
O=C1CN[Fe+2]2(NCC(=O)[O-]2)[O-]1
LogP
-3.47 at · -3.47 at 20℃ and pH7
表面張力
72.87 mN/m · 72.87mN/m at 1g/L and 20℃

安全と法規制

安全情報は参考情報です。供給元の安全データシート(SDS)、適用法令、専門家による評価に代わるものではありません。

GHS分類

GHS Classification · 5 件

This chemical does not meet GHS hazard criteria for 2.5% (4 of 162) of reports.

Warning

H302 (32.7%): Harmful if swallowed [Warning Acute toxicity, oral]

P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P321, P330, P332+P317, P337+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 162 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Regulatory Information · 3 件

Regulation (EC) No 178/2002 (amended)

REACH registered substance: Iron, bis(glycinato-.kappa.N,.kappa.O)- (EC: 606-444-7)

Ferrous bisglycinate: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazard Classes and CategoriesAcute Tox. 4 (32.7%)

安全データ

毒性
LD50 orally in rats: 560 mg iron/kg (Jeppsen)

化学と産業

用途と製造

Use ClassificationFood Additives -> NUTRIENT_SUPPLEMENT -> JECFA Functional Classes
応用分野 · 2 件

説明Ferrous Bisglycinate, also known as ferrous glycinate, is an iron (II) chelate with an iron to glycine ratio of 1:2. It has an octahedral structure with two water molecules and two chelated glycinate ions coordinated to the central ferrous iron. Ferrous glycinate (processed with citric acid) also contains citric acid. It is manufactured by reaction of reduced iron with glycine in the presence of citric acid. The resulting product is spray dried without prior removal of the citric acid. The substance is highly hygroscopic and may contain water in variable amounts.

使用Ferrous Bisglycinate is an iron-amio acid chelate. In this the iron is protected from the action of absorption inhibitors by being bound to the amino acid and glycine. Ferrous bisglycinate is the major amino acid chelate produced commercially, although ferrous trisglycinate and ferric glycinate are also available. A patented ferrous bisglycinate compound, manufactured by Albion Laboratories, Utah, USA, has been used in most published studies. The chelate is reported to be formed by two glycine molecules combining with ferrous iron in a double heterocyclic ring structure. Evidence would suggest that iron is protected from inhibitors by the structure, since iron absorption is one to 3.5 times higher than from ferrous sulfate when added to bread rolls and milk products containing inhibitors such as phytate and calcium. Ferrous bisglycinate is more bioavailable than ferrous trisglycinate.

サプライヤー108 社

Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]
山东天微医药科技有限公司+86-18653895227 · [email protected]
上海康朗生物科技有限公司021-61998208 18217752821 · [email protected]

関連反応

2 件
反応記録を作成
HRID 387489 の反応式
HRID 387489生成物としてuspto-grants-2013_02
HRID 504074 の反応式
HRID 504074反応物としてuspto-grants-2010_08

化合物ノート

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