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Aluminum magnesium oxide (Al2MgO4)

HCID 9855501
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基本情報概要名称と識別子物性安全と法規制化学と産業関連反応化合物ノート
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基本情報

CAS
11137-98-7
標準SMILES
[Al+3].[Al+3].[Mg+2].[O-2].[O-2].[O-2].[O-2]
InChIKey
HDRHAXQZSKYGMK-UHFFFAOYSA-N
分子式
Al2MgO4
平均分子量
142.27 g/mol
単同位体質量
141.927777

概要

Magnesium aluminate is a chemical compound of magnesium and aluminum. Aluminum is the most abundant metal in the earth's crust and is always found combined with other elements such as oxygen, silicon, and fluorine. (L739, L740)

名称と識別子

優先名称
Aluminum magnesium oxide (Al2MgO4)
IUPAC
dialuminum;magnesium;tetrakis(oxygen(2-))
英語名
Aluminum magnesium oxide
分子式
Al2Mg2O5
分子量
182.570076

名称と別名

Alumina magnesiaCernel IAluminum magnesium oxide (Al2MgO4)PAJ0L824IZAluminate (AlO21-), magnesium (2:1)RefChem:1076604MAGNESIUM(2+) ION DIALUMANOYLOLATE235-100-512068-51-8Magnesium AluminateDialuminium magnesium tetraoxideMagnesium aluminate (MgAl2O4)
名称をさらに表示
Aluminum magnesium oxide
Dialuminum magnesium tetraoxideMagnesium aluminate (Mg(AlO2)2)Aluminum magnesium oxide (MgAl2O4)EINECS 235-100-5Magnesium aluminum oxide (MgAl2O4)dialuminum;magnesium;oxygen(2-)Magnesium aluminum oxideSCHEMBL19327583

データベース識別子

CAS
11137-98-7、12068-51-8
PubChem CID
9855501
UNII
PAJ0L824IZ
EC Number
235-100-5

物性

構造計算による物性

極性表面積
4 Ų
水素結合供与体数
0
水素結合受容体数
4
回転可能結合数
0
重原子数
7
形式電荷
0
複雑度
0

実験および物理化学的性質

Chemical ClassesMetals -> Metals, Inorganic Compounds
SpringerMaterials Properties · 2 件

crystal structure

enthalpy change

Physical DescriptionWhite odorless solid in various forms; [Alfa Aesar MSDS]

物理化学的性質

水溶解度
13 μg/L · 13μg/L at 20℃
化粧品成分の機能
増量剤吸収性口腔ケア固結防止
LogP
-1.38 · -1.380 (est)
EPAの化学物質情報
Aluminum magnesium oxide (11137-98-7)

安全と法規制

安全情報は参考情報です。供給元の安全データシート(SDS)、適用法令、専門家による評価に代わるものではありません。

GHS分類

GHS Classification · 5 件

This chemical does not meet GHS hazard criteria for 54.5% (6 of 11) of all reports.

Warning

H315 (45.5%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 11 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

危険有害性情報

Regulatory InformationChemical: Aluminate (AlO21-), magnesium (2:1)
Hazards SummaryMay cause irritation; [Alfa Aesar MSDS] See Aluminum.
Hazard Classes and CategoriesSkin Irrit. 2 (45.5%)

安全と保護具

Exposure Control and Personal Protection4.0 [mg/m3], (inhalable fraction), 1.5 mg/m3 (respirable fraction)[German Research Foundation (DFG)]
Minimum Risk LevelIntermediate Oral: 1.0 mg/kg/day (L134) Chronic Oral: 1.0 mg/kg/day (L134)
Threshold Limit Values (TLV)1.0 [mg/m3], respirable fraction
Permissible Exposure Limit (PEL)15.0 [mg/m3](total dust), 5 mg/m3(respirable fraction)

毒性情報

化学と産業

薬理情報

Metabolism/Metabolites · 1 件

Aluminum is poorly absorbed following either oral or inhalation exposure and is essentially not absorbed dermally. The bioavailability of aluminum is strongly influenced by the aluminum compound and the presence of dietary constituents which can complex with aluminum and enhance or inhibit its absorption. Aluminum binds to various ligands in the blood and distributes to every organ, with highest concentrations found in bone and lung tissues. In living organisms, aluminum is believed to exist in four different forms: as free ions, as low-molecular-weight complexes, as physically bound macromolecular complexes, and as covalently bound macromolecular complexes. Absorbed aluminum is excreted principally in the urine and, to a lesser extent, in the bile, while unabsorbed aluminum is excreted in the faeces. (L739)

用途と製造

General Manufacturing InformationAluminate (AlO21-), magnesium (2:1): ACTIVE

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化合物ノート

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このページの内容基本情報概要名称と識別子物性安全と法規制化学と産業関連反応化合物ノート
Treatment · 1 件

EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration.

Health Effects · 1 件

Aluminum targets the nervous system and causes decreased nervous system performance and is associated with altered function of the blood-brain barrier. The accumulation of aluminum in the body may cause bone or brain diseases. High levels of aluminum have been linked to Alzheimer's disease. A small percentage of people are allergic to aluminium and experience contact dermatitis, digestive disorders, vomiting or other symptoms upon contact or ingestion of products containing aluminium. (L739, L740)

Exposure RoutesOral (L739) ; inhalation (L739)
Toxicity Summary · 1 件

The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphorus. The decreased phosphate body burden results in osteomalacia (softening of the bones due to defective bone mineralization) and rickets. Aluminum's neurotoxicity is believed to involve several mechanisms. Changes in cytoskeletal protein functions as a results of altered phosphorylation, proteolysis, transport, and synthesis are believed to be one cause. Aluminum may induce neurobehavioral effects by affecting permeability of the blood-brain barrier, cholinergic activity, signal transduction pathways, lipid peroxidation, and impair neuronal glutamate nitric oxide-cyclic GMP pathway, as well as interfere with metabolism of essential trace elements because of similar coordination chemistries and consequent competitive interactions. It has been suggested that aluminum's interaction with estrogen receptors increases the expression of estrogen-related genes and thereby contributes to the progression of breast cancer (A235), but studies have not been able to establish a clear link between aluminum and increased risk of breast cancer (A15468). Certain aluminum salts induce immune responses by activating inflammasomes. (L739, A235, A236)

Signs and Symptoms · 1 件

Inhalating aluminum dust causes coughing and abnormal chest X-rays. A small percentage of people are allergic to aluminium and experience contact dermatitis, digestive disorders, vomiting or other symptoms upon contact or ingestion of products containing aluminium. (L739, L740)

Carcinogen Classification · 1 件

Not listed by IARC. IARC classified aluminum production as carcinogenic to humans (Group 1), but did not implicate aluminum itself as a human carcinogen. (L135) A link between use of aluminum-containing antiperspirants and increased risk of breast cancer has been proposed (A235), but studies have not been able to establish a clear link (A15468).

安全データ

tsca
TSCA listed