Acetaminophen; Aspirin; Caffeine

HCID 9871508CAS 83535-74-4

基本情報

標準SMILES: CC(=O)Nc1ccc(O)cc1.CC(=O)Oc1ccccc1C(=O)O.Cn1c(=O)c2c(ncn2C)n(C)c1=O
InChIKey: BKMBGNWZSQNIKU-UHFFFAOYSA-N
分子式: C25H27N5O8
平均分子量: 525.5 g/mol

概要

Acetaminophen/Aspirin/Caffeine is a commercial combination preparation by Novartis containing acetaminophen, aspirin, and caffeine with analgesic activity. Acetaminophen exerts antipyretic and analgesic activities by inhibiting prostaglandin synthesis while aspirin, a salicylate, inhibits cyclooxygenases (COX) with anti-inflammatory, antipyretic and analgesic properties. Caffeine is a central nervous system stimulant and causes constriction of dilated cerebral blood vessels. Excedrin is used for the relief and treatment of migraine and tension headaches.

名称と識別子

優先名称: Acetaminophen; Aspirin; Caffeine
IUPAC: 2-acetyloxybenzoic acid;N-(4-hydroxyphenyl)acetamide;1,3,7-trimethylpurine-2,6-dione

名称と別名

Acetaminophen / aspirin / caffeineSeedalmerkArthritenExtraprinArthritenMaxExcedrinMigrainemigraine formulaDolex ForteHeadache FormulaExcedrin MigraineXpect Pain AwayPain Free Plus

名称をさらに表示

Medique Pain OffPain Reliever 2ConRx pain RelieverHeadache, Circle KCove Migraine ReliefDOLODOLSohMed Pain RelieverExcedrinExtra Strength

データベース識別子

CAS: 83535-74-4
PubChem CID: 9871508

物性

構造計算による物性

極性表面積: 171 Å²
水素結合供与体数: 3
水素結合受容体数: 9
回転可能結合数: 4
重原子数: 38
形式電荷: 0
複雑度: 644

実験および物理化学的性質

Human DrugsFDA approved drugs -> Active ingredient

安全と法規制

毒性情報

Adverse EffectsCaffeine

Toxicity SummaryCaffeine