Acryloylmorpholine (HCID 98723)

名称と識別子

優先名称: Acryloylmorpholine
IUPAC: 1-morpholin-4-ylprop-2-en-1-one
現地名: 4-アクリロイルモルホリン
英語名: 4-Acryloylmorpholine
分子式: C7H11NO2
分子量: 141.17

名称と別名

5117-12-4acryloylmorpholineACRYLOYL MORPHOLINE4-(1-oxo-2-propenyl)-morpholineDTXSID0044947K0Y58P61JANSC-1622212-Propen-1-one, 1-(4-morpholinyl)-DTXCID8024947RefChem:1076142418-140-1610-626-1

名称をさらに表示

4-アクリロイルモルホリン4-プロペノイルモルホリンN,N-(オキシビスエチレン)アクリルアミド1-(4-モルホリニル)-2-プロペン-1-オン4-アクリリルモルホリンアクリルモルホリドN-アクリロイルモルホリン1-モルホリノ-2-プロペン-1-オンビニルモルホリノケトンACMOアクリロイルモルホリン1-(モルホリン-4-イル)プロパ-2-エン-1-オン1-モルホリノアクリルアルデヒド1-(モルホリン-4-イル)プロペナールモルホリン-4-イルエテニルケトンACMOyyyy-m-d4-AcryLAcrylmorpholideAcryloylmorpholin

4-Acryloylmorpholine1-Morpholinoprop-2-en-1-oneN-AcrylylmorpholineN-AcryloylmorpholineMorpholine, 4-(1-oxo-2-propenyl)-1-(Morpholin-4-yl)prop-2-en-1-one1-morpholin-4-ylprop-2-en-1-one4-(1-Oxo-2-propenyl)morpholine

データベース識別子

CAS: 5117-12-4
PubChem CID: 98723
DTXSID: DTXSID0044947
ChEMBL: CHEMBL3187188
UNII: K0Y58P61JA
EC Number: 418-140-1、610-626-1
Nikkaji: J87.318G

物性

構造計算による物性

XLogP: -0.1
極性表面積: 29.5 Å²
水素結合供与体数: 0
水素結合受容体数: 2
回転可能結合数: 1
重原子数: 10
形式電荷: 0
複雑度: 139

物理化学的性質

融点: 35 °C · −35 °C(lit.)
沸点: 158 °C · 158°C 50mm
比重(密度): 1.122 g/mL · 1.122 g/mL at 25 °C(lit.)
蒸気圧: 1.03 · 1.03-1.64Pa at 25-29.9℃
屈折率: 20 · n20/D 1.512(lit.)
闪点: 230 °F · >230 °F
貯蔵温度: 2 · 2-8°C
溶解性: Soluble in water
外見: 液体
酸解離定数(Pka): -1.08 · -1.08±0.20(Predicted)
色: 無色～黄色
水溶解度: 1000 g/L · 1000g/L at 20℃
BRN: 119302 · 119302
化粧品成分の機能: 可塑剤
InChI: 1S/C7H11NO2/c1-2-7(9)8-3-5-10-6-4-8/h2H,1,3-6H2
InChIKey: XLPJNCYCZORXHG-UHFFFAOYSA-N
SMILES: C=CC(=O)N1CCOCC1
LogP: -0.46 at · -0.46 at 20.5-21℃
CAS データベース: 5117 · 5117-12-4(CAS DataBase Reference)
NISTの化学物質情報: N-acryloylmorpholine(5117-12-4)
EPAの化学物質情報: 4 · Morpholine, 4-(1-oxo-2-propenyl)- (5117-12-4)

化学的性質

化学的特性4-Acryloylmorpholine has a melting point of 35 °C and is clear liquid at room temperature. At 25 °C, it has a density of 1.122 g/mL. It needs to be stored at 2-8°C.

安全と法規制

GHS分類

GHS Classification · 6 件

Danger

H302: Harmful if swallowed [Warning Acute toxicity, oral]

P260, P261, P264, P264+P265, P270, P272, P280, P301+P317, P302+P352, P305+P354+P338, P317, P319, P321, P330, P333+P317, P362+P364, and P501 (click each P-code to see the statement)

Danger

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

P260, P261, P264, P264+P265, P270, P271, P272, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P316, P317, P319, P321, P330, P333+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

危険有害性情報

Regulatory Information · 4 件

Chemical: Morpholine, 4-(1-oxo-2-propenyl)-

PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

Status: No longer Valid Update: 10-11-2008 https://echa.europa.eu/registration-dossier/-/registered-dossier/9420

Acryloyl morpholine: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationEvaluation - Morpholine, 4-(1-oxo-2-propenyl)- (acryloyl morpholine)

Hazard Classes and Categories · 5 件

Acute Tox. 4 (100%)

Acute toxicity - category 4

Acute toxicity (Oral) - Category 4

Acute Tox. 4 *

安全データ

wgk: 2
tsca: TSCA listed
hs_code: 29349990
risk_code: 22-41-43-48/22
化審法: (5)-865
消防法: 危-4-3-III
hazard_code: Xn
safety_code: 23-26-36/37/39
Hazard Classifications: Acute Tox. 4 OralEye Dam. 1Skin Sens. 1STOT RE 2 Oral
ストレージクラス: 10 - Combustible liquids

化学と産業

用途と製造

General Manufacturing Information2-Propen-1-one, 1-(4-morpholinyl)-: ACTIVE

応用分野 · 2 件

説明4-Acryloylmorpholine (4-AM) is a water-soluble monomer, an acrylamide derivative containing a heterocyclic tetrahydrooxazine substituent. Homo- and copolymers of 4-АМ have several valuable properties. They are soluble both in water and in many organic solvents such as alcohols, chloroform, tetrahydrofuran, and dioxane, are non-toxic, and are used for solid-phase synthesis of peptides in chromatography, as materials for composite semipermeable membranes, in catalysis, and for biomedical purposes. Various functional groups are introduced into poly-4-AM to expand its application fields. Random copolymers of 4-АМ with carboxylic acids (acrylic, 4-pentenoic, undecenoic, 2-acrylamido-2-methyl-1-propanesulfonic), behaving as anionic polyelectrolytes, and copolymers with N-hydroxysuccinimide ester of acrylic acid, acting as polymeric carriers, have been synthesized[2-3].

使用4-Acryloylmorpholine is used in adhesives, UV curable resins, industrial coatings, UV printing ink, oil recovery polymer, medicinal and commodity chemicals.